Hotels in Greater South Side

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23 Dec - 24 Dec
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24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Greater South Side hotels

Desk, iron/ironing board, free cots/infant beds, rollaway beds
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1692)
"Had a great stay and was impressed with the staff and the hotel. Will stay again!"
United States
Kevin
The price is S$91
includes taxes & fees
6 Jan - 7 Jan, 2026
Days Inn & Suites by Wyndham Des Moines Airport
Free daily buffet breakfast
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.4 out of 10, Good, (1000)
"Great staff very helpful. "
United States
Cleo and Michaelle
The price is S$89
includes taxes & fees
1 Jan - 2 Jan, 2026
Quality Inn & Suites Des Moines Airport
Reception
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
2.5 star property
Greater South Side
7.8 out of 10, Good, (1002)
"The staff was great, check in was fast and easy"
United States
Joel
The price is S$89
includes taxes & fees
20 Jan - 21 Jan, 2026
AmericInn by Wyndham Des Moines Airport
Property amenity
Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.2 out of 10, Very good, (597)
"Great staff, clean room "
United States
Kenny
The price is S$158
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Des Moines-Airport/Conf Center by IHG
Free daily continental breakfast
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1001)
"Friendly staff, clean room, comfy bed, and convenient shuttle."
United States
Cullanete
The price is S$152
includes taxes & fees
2 Jan - 3 Jan, 2026
Hampton Inn Des Moines-Airport
Free WiFi, bed sheets
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA
2.0 star property
15.3 km from Greater South Side
7.8 out of 10, Good, (718)
"Nice clean room, friendly staff. "
United States
Cheryl
The price is S$73
includes taxes & fees
6 Jan - 7 Jan, 2026
Motel 6 West Des Moines, IA
Free daily full breakfast
Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG
2.5 star property
17.5 km from Greater South Side
9.4 out of 10, Exceptional, (298)
"clean, friendly staff, room was well equipped"
United States
Colin
The price is S$122
includes taxes & fees
3 Jan - 4 Jan, 2026
Holiday Inn Express Des Moines Ankeny by IHG
Exterior
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 4.5 km from Greater South Side
9.4 out of 10, Exceptional, (1000)
"The check in lady was a grouchy old bag."
United States
David
The price is S$124
includes taxes & fees
29 Dec - 30 Dec
Staybridge Suites Des Moines Downtown by IHG
Indoor pool
La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines
3.0 star property
17.4 km from Greater South Side
9.0 out of 10, Wonderful, (1535)
"Very nice staff member upon check in. Very nice hotel and well kept. "
United States
Debra
The price is S$114
includes taxes & fees
12 Jan - 13 Jan, 2026
La Quinta by Wyndham Altoona Des Moines
Lobby
Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines
2.5 star property
18.8 km from Greater South Side
9.2 out of 10, Wonderful, (671)
"Great place to stay!"
United States
Donald J
The price is S$130
includes taxes & fees
3 Jan - 4 Jan, 2026
Hampton Inn & Suites Altoona-Des Moines
Free daily buffet breakfast
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines
3.0 star property
12.3 km from Greater South Side
9.4 out of 10, Exceptional, (1001)
"A great place to stay"
United States
Carol
The price is S$144
includes taxes & fees
2 Jan - 3 Jan, 2026
Drury Inn & Suites West Des Moines
Lobby
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West
2.5 star property
14.9 km from Greater South Side
9.0 out of 10, Wonderful, (1006)
"Room was clean, staff was courteous and the bed was comfortable. "
United States
Craig
The price is S$119
includes taxes & fees
5 Jan - 6 Jan, 2026
Fairfield Inn and Suites by Marriott Des Moines West
Exterior
Courtyard Marriott Ankeny

Courtyard Marriott Ankeny

Courtyard Marriott Ankeny
3.0 star property
17.9 km from Greater South Side
8.8 out of 10, Excellent, (540)
"Location, easy check in, welcoming vibe. "
United States
Denise
The price is S$121
includes taxes & fees
27 Dec - 28 Dec
Courtyard Marriott Ankeny
Free daily buffet breakfast
Hotel Pommier Indianola

Hotel Pommier Indianola

Hotel Pommier Indianola
2.5 star property
20.9 km from Greater South Side
9.2 out of 10, Wonderful, (435)
"Loved it! Quaint and perfect stay! "
United States
Kara
The price is S$102
includes taxes & fees
1 Jan - 2 Jan, 2026
Hotel Pommier Indianola
Lobby
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills, 6.2 km from Greater South Side
9.4 out of 10, Exceptional, (1167)
"Convenient location to restaurants"
United States
Sally
The price is S$124
includes taxes & fees
20 Jan - 21 Jan, 2026
Baymont by Wyndham Des Moines Airport
In-room safe, desk, iron/ironing board, free WiFi
Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines
2.0 star property
17.7 km from Greater South Side
8.2 out of 10, Very good, (756)
"The room is quite comfortable Well maintained and clean "
United States
Dale
The price is S$80
includes taxes & fees
26 Dec - 27 Dec
Econo Lodge Ankeny - Des Moines
Lobby
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 3.7 km from Greater South Side
9.6 out of 10, Exceptional, (1066)
"Comfy and stylish lobby and rooms, delicious cafe"
United States
Sarah
The price is S$205
includes taxes & fees
18 Jan - 19 Jan, 2026
Hotel Fort Des Moines, Curio Collection by Hilton
Free buffet breakfast
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
3.0 star property
18 km from Greater South Side
9.2 out of 10, Wonderful, (1000)
"Great stay with dogs"
United States
Mindy
The price is S$113
includes taxes & fees
1 Jan - 2 Jan, 2026
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
Indoor spa tub
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston
2.5 star property
14.3 km from Greater South Side
8.8 out of 10, Excellent, (1793)
"The breakfast and coffee was absolutely amazing. "
United States
Brenda
The price is S$141
includes taxes & fees
5 Jan - 6 Jan, 2026
Stoney Creek Hotel Des Moines - Johnston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Greater South Side

Find the best Greater South Side areas for the activities you enjoy most.
State Historical Society of Iowa Museum featuring a high-rise building, landscape views and a city

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

Historic East Village

Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Science Center of Iowa and Principal Park while you're in town.

Drake

While visiting Drake, you might make a stop by sights like Knapp Center and Des Moines Community Playhouse.

Southwestern Hills

Though Southwestern Hills may not have many top sights, you can venture to the surrounding area to see attractions like Air Lanes Bowling Center and Gray’s Lake Park.

Top Greater South Side Hotel Reviews

Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

10/10 Excellent
"A great place to stay"
Carol 1-night trip
Posted 3 days ago
Drury Inn & Suites West Des Moines

Frequently asked questions

What's it like in Greater South Side?
Travellers are sure to enjoy a stay in Des Moines's Greater South Side neighbourhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
What's the best accommodation in Greater South Side?
Based on Expedia customer reviews, Days Inn & Suites by Wyndham Des Moines Airport is the highest ranked property in Greater South Side. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport.
How many hotels can I expect to find in Greater South Side?
With 16 Expedia hotels and other accommodation options in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Greater South Side.
What is there to do around this Des Moines neighbourhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

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