Hotels near Lewis and Clark Interpretive Center
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Lewis and Clark Interpretive Center hotels

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City6.2 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (488)
The price is S$160
includes taxes & fees
11 Jan - 12 Jan, 2026

Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach6.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (806)
The price is S$122
includes taxes & fees
4 Jan - 5 Jan, 2026

8.6 out of 10, Excellent, (196)
The price is S$124
includes taxes & fees
30 Dec - 31 Dec

Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach5.5 km from Lewis and Clark Interpretive Center
7.8 out of 10, Good, (581)
The price is S$85
includes taxes & fees
30 Dec - 31 Dec

Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG10.9 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (823)
The price is S$171
includes taxes & fees
4 Jan - 5 Jan, 2026

Comfort Inn Edwardsville - St. Louis
Comfort Inn Edwardsville - St. Louis9.4 km from Lewis and Clark Interpretive Center
8.4 out of 10, Very good, (809)
The price is S$150
includes taxes & fees
18 Jan - 19 Jan, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Lewis and Clark Interpretive Center Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch
10/10 Excellent


















































































