Hotels near Main Street

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Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Main Street hotels

Terrace/patio
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1001)
"Staff member Sandy very congenial when we checked in. Laid back atmosphere (early December). Will consider for future Hyannis stay."
United States
Lawrence
The price is S$242
includes taxes & fees
28 Dec - 29 Dec
Anchor In Distinctive Waterfront Lodging
Lobby
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.5 star property
9.1 km from Main Street
8.8 out of 10, Excellent, (662)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is S$162
includes taxes & fees
1 Jan - 2 Jan, 2026
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
View from property
Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (489)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is S$180
includes taxes & fees
11 Jan - 12 Jan, 2026
Courtyard By Marriott Cape Cod Hyannis
Exterior
Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (977)
"Check in was easy and the front desk person was wonderful. "
United States
Anastasios
The price is S$141
includes taxes & fees
1 Jan - 2 Jan, 2026
Holiday Inn Hyannis by IHG
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Bayside Resort Hotel

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
11.2 km from Main Street
8.8 out of 10, Excellent, (1524)
"Reception staff was warm and welcoming! "
United States
Liza
Bayside Resort Hotel
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1001)
"Rooms were spotless, staff was wonderful and very accommodating. Amenities were great… coffee, tea and hot chocolate in lobby 24 hours a day. Lobby was decorated for Christmas and the holiday season… made for a very festive stay. Breakfast was awesome too!!!"
United States
Deborah
The price is S$167
includes taxes & fees
1 Jan - 2 Jan, 2026
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool
Courtyard Resort

Courtyard Resort

Courtyard Resort
2.0 star property
8.8 km from Main Street
8.2 out of 10, Very good, (46)
"Clean and inexpensive"
United States
Robert
The price is S$160
includes taxes & fees
8 Jan - 9 Jan, 2026
Courtyard Resort
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.0 out of 10, Very good, (1000)
"Nice hotel had a perfect stay"
United States
David
The price is S$144
includes taxes & fees
2 Jan - 3 Jan, 2026
Comfort Inn Hyannis - Cape Cod
View from room
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
10.9 km from Main Street
9.4 out of 10, Exceptional, (97)
"Hotel was quiet and very clean , pool water was cool"
United States
Robyn
The price is S$156
includes taxes & fees
28 Dec - 29 Dec
Uncommoner Hotel by Reverie Boutique Collection
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
9.1 km from Main Street
8.0 out of 10, Very good, (1000)
"Amazing place "
United States
Mounir
The price is S$211
includes taxes & fees
25 Jan - 26 Jan, 2026
Hyannis Harbor Hotel
Outdoor pool, pool umbrellas, pool loungers
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
8.7 km from Main Street
8.8 out of 10, Excellent, (418)
"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "
United States
Stephen
The price is S$286
includes taxes & fees
4 Jan - 5 Jan, 2026
Margaritaville Resort Cape Cod
Exterior
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (878)
"Nice room, freindly staff. The downside is the food was pricey. "
United States
Steffanie
The price is S$167
includes taxes & fees
4 Jan - 5 Jan, 2026
Doubletree by Hilton Cape Cod - Hyannis
Private beach nearby, beach bar
The Club at New Seabury

The Club at New Seabury

The Club at New Seabury
3.5 star property
10.3 km from Main Street
9.0 out of 10, Wonderful, (340)
"Very relaxing, loved the different clubs available; beach, pool, tennis, playground for the little ones, bars and food. Some shops were closed due to being off season, but still enjoyed our stay. Looking forward to booking again "
United States
Jose O.
The Club at New Seabury
Front of property – evening/night
Cape Cod Hotel

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
8.8 km from Main Street
7.4 out of 10, Good, (1000)
"Great stay"
United States
Vanuze
The price is S$159
includes taxes & fees
2 Jan - 3 Jan, 2026
Cape Cod Hotel
Beach nearby
The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
11.2 km from Main Street
9.2 out of 10, Wonderful, (243)
"Great place to stay. Clean, friendly and accommodating!"
United States
Mike
The price is S$189
includes taxes & fees
8 Jan - 9 Jan, 2026
The Cove at Yarmouth by Westgate Resorts
Garden
The Village Inn Cape Cod

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
14.3 km from Main Street
10.0 out of 10, Exceptional, (223)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is S$248
includes taxes & fees
27 Dec - 28 Dec
The Village Inn Cape Cod
Exterior
Cape Sands Inn

Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1014)
"Clean room courteous staff and easy check in "
United States
Linda
The price is S$110
includes taxes & fees
28 Dec - 29 Dec
Cape Sands Inn
Exterior
Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
12.4 km from Main Street
8.0 out of 10, Very good, (1000)
"Nice room and nice staff"
United States
Jessica
The price is S$140
includes taxes & fees
31 Dec - 1 Jan, 2026
Aiden by Best Western Cape Cod - West Yarmouth
Individually decorated, individually furnished, desk, laptop workspace
Harborside Suites

Harborside Suites

Harborside Suites
2.0 star property
15.1 km from Main Street
6.6 out of 10, (189)
"Nice hotel "
United States
Sergio
Harborside Suites
Lobby
Hyannis Plaza Hotel

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
8.2 km from Main Street
7.0 out of 10, Good, (974)
"good stay for night"
United States
David
The price is S$117
includes taxes & fees
23 Jan - 24 Jan, 2026
Hyannis Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hotel Reviews

Courtyard Resort

Courtyard Resort

10/10 Excellent
"Room what nice very easy check in.. The only thing is the toilet flooded our room but they moved us to another unit no problem! I always enjoy my stay at courtyard resort"
Michael 1-night trip
Posted 6 days ago
Courtyard Resort

Hotels near other Main Street attractions

Peaceful warm seascape with brown beach bench and Rose Hip bushes on Falmouth Height Beach on Cape Cod. at Dawn

Falmouth Heights Beach

4.4/5 (159 reviews)
Why not spend a care-free afternoon at Falmouth Heights Beach during your travels in Falmouth? While you're in the area, stroll along the seaside.
See properties
Surf Drive Beach featuring a beach and a coastal town

Surf Drive Beach

4.5/5 (51 reviews)
Gorgeous views across Vineyard Sound and close proximity to Falmouth’s town center make this Cape Cod beach both scenic and convenient.
See properties

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, take a look at the 24 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Other good choices within 5 miles include Craigville Beach Inn and The Ocean View.
How many hotels will I be able to find near Main Street?
Expedia has 24 hotels and other accommodation options within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best options available near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cotuit Center for the Arts, Cape Cod Melody Tent and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Dowses Beach and Keyes Beach.