Hotels near Main Street Hyannis, Hyannis

A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

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Our top choices for Main Street Hyannis hotels

A multi-story hotel with balconies, a flat roof, and a clear sky.

A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

A man sitting at a table with a laptop, overlooking a pool area with chairs and tables.

A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.

1. Hyannis Travel Inn

0.2 km from Main Street Hyannis

David J

S$145

includes taxes & fees

7 Oct - 8 Oct

A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.

A kitchen counter with a knife and a cutting board, a sign with a flower, and a view of a dining area through glass doors.

A two-story building with a covered porch and a sign for Sea Street Inn.

A dining area with black leather chairs, dark wooden tables, and white bowls.

2. Sea Street Inn

1.5 km from Main Street Hyannis

John

S$404

includes taxes & fees

25 Oct - 26 Oct

A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.

A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

A hotel with a pool area, outdoor seating, and a flag.

A corridor with wooden flooring, wicker furniture, and large windows.

3. Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

kathy

S$235

includes taxes & fees

1 Nov - 2 Nov

A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".

A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.

A bar area with a patterned wall, wicker chairs, and a tiled floor.

A modern indoor dining area with a wooden table, chairs, and a decorative wall with string lights.

4. Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

Monique

S$175

includes taxes & fees

1 Nov - 2 Nov

A pool area with lounge chairs and flags.

A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

A beachside seating area with Adirondack chairs arranged around a stone fire pit.

A modern building with a sloped roof, large windows, and a covered entrance area with seating.

5. The Cove at Yarmouth by Westgate Resorts

2.1 km from Main Street Hyannis

BELKIS

S$172

includes taxes & fees

4 Nov - 5 Nov

A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.

A spacious, modern restaurant with a long counter and multiple seating areas.

An indoor swimming pool with lounge chairs, a stone wall, and a mezzanine level.

A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.

6. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

0.3 km from Main Street Hyannis

Berita

S$185

includes taxes & fees

26 Oct - 27 Oct

A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.

A modern reception area with a desk, chairs, a fireplace, and a decorative plant.

A Fairfield by Marriott hotel with a large sign, a covered entrance, and a building with a tower.

A hotel room with a bed, a TV, a sofa, a lamp, and a chair.

7. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

Joyce

S$185

includes taxes & fees

26 Oct - 27 Oct

An outdoor patio with wicker furniture, a fire pit, and umbrellas.

An indoor swimming pool with clear signage, lounge chairs, and a tiled floor.

A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.

A snack and drink kiosk with a 'Treats' sign, a chalkboard menu, and shelves stocked with various snacks and beverages.

8. Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

Carmen E

S$167

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.

A hotel room with a bed, a chair, a table with two glasses of wine, a lamp, and a window with a view of a lake.

A beach scene with a directional signpost and beach chairs.

A beachside table with two chairs, a blue umbrella, and a white tablecloth.

9. Bayside Resort Hotel

2.3 km from Main Street Hyannis

Lynn

S$139

includes taxes & fees

3 Nov - 4 Nov

An indoor swimming pool with a high ceiling and large windows.

A café interior with a wooden counter, a menu board, and a refrigerated display.

A hotel reception area with a digital display showing today's weather and this week's forecast.

10. Courtyard By Marriott Cape Cod Hyannis

1.7 km from Main Street Hyannis

SHREYASI

S$199

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a brick wall, a white table with chairs, and a large window.

A reception area with a reception desk, a clock, a fire alarm, and a sign for the courtyard resort.

A compact hotel room with a kitchenette, a bed, a dining area, and a view through a large window.

A multi-story hotel with a well-maintained lawn, outdoor seating area with chairs, and a wooden deck.

11. Courtyard Resort

0.3 km from Main Street Hyannis

Jeffrey

S$145

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.

A DoubleTree hotel with a brick facade and a large sign.

A large indoor swimming pool with multiple lanes, surrounded by rows of chairs and a high ceiling with large windows.

A lobby with a stone wall, a TV, and seating areas.

12. Doubletree by Hilton Cape Cod - Hyannis

0.9 km from Main Street Hyannis

Tammie

S$190

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.

A neatly made bed with white linens, a painting of a sailboat on the wall, and a door leading to a balcony.

A row of white buildings with balconies, outdoor seating, and flower beds.

A lobby with a wooden floor, a reception desk, a large window, and a ceiling fan.

13. Cape Sands Inn

1.9 km from Main Street Hyannis

Jerome

S$115

includes taxes & fees

7 Oct - 8 Oct

A two-story hotel with a curved facade, a balcony, and a sign indicating the lobby.

An outdoor seating area with wicker furniture, umbrellas, and a stone wall.

A modern living room with two sofas, a coffee table, and a stone wall with a fireplace.

A resort pool area with multiple lounge chairs and umbrellas, a hot tub, and a large building in the background.

14. Hyannis Harbor Hotel

0.6 km from Main Street Hyannis

Jayne

S$201

includes taxes & fees

19 Oct - 20 Oct

A gym with various cardio and strength training equipment, including treadmills, elliptical machines, and weight machines.

A swimming pool with chairs and umbrellas, surrounded by a fence and greenery.

A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

A hotel room with a gray sofa, a television on a stand, a sliding door, a framed picture on the wall, and a lamp on a side table.

15. Holiday Inn Hyannis by IHG

2.9 km from Main Street Hyannis

Alexander

S$186

includes taxes & fees

25 Oct - 26 Oct

A long dining table with chairs, a kitchen area, and a large window.

A reception area with a check-in counter, blue chairs, a waiting area, and a glass door leading to a dining area.

An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.

A hotel room with a bed, a desk with a flat-screen TV, a coffee maker, a microwave, a vacuum cleaner, and a sliding door to a balcony.

16. Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

claire

S$167

includes taxes & fees

1 Nov - 2 Nov

A beach with clear skies and gentle waves.

A grassy area with blue Adirondack chairs arranged around a central fire pit. In the background, there are two buildings with a playground structure.

A reception area with a wooden counter, a blue accent wall, and striped armchairs.

A fire pit with chairs arranged around it, set on sandy ground with a wooden fence and foliage in the background.

17. Sunbird Cape Cod Resort

2.3 km from Main Street Hyannis

Kent

S$132

includes taxes & fees

12 Oct - 13 Oct

A modern living room with a sofa, coffee table, and kitchen area with appliances.

A bedroom with a bed, a dresser, a TV, a window with blinds, and an air conditioner.

A sign for Hyannis Host Inn with a building in the background.

A building with a covered entrance, a parking lot, and a tree with pink blossoms.

18. Hyannis Host Inn

1.6 km from Main Street Hyannis

Keith

S$167

includes taxes & fees

7 Oct - 8 Oct

An indoor swimming pool with a covered area, poolside chairs, and a table.

A white building with large windows and a blue sign indicating it is a bank.

A spacious living area with a large TV, comfortable seating, and a view of the outside.

A hotel room with a large bed, two bedside lamps, a nightstand, a framed picture on the wall, and a curtain.

19. Americas Best Value Inn & Suites Hyannis Cape Cod

0.5 km from Main Street Hyannis

Linda

S$130

includes taxes & fees

7 Oct - 8 Oct

A swimming pool with clear blue water, surrounded by a tiled deck and a building with a green roof in the background.

20. Sunbird ANNEX Resort

2.3 km from Main Street Hyannis

Evroy

S$134

includes taxes & fees

8 Oct - 9 Oct

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Compare popular hotels close to Main Street Hyannis

Property	Property class	Guest rating
Hyannis Travel Inn	9.6 Exceptional 1,015 reviews	View
Sea Street Inn	9.8 Exceptional 47 reviews	View
Anchor In Distinctive Waterfront Lodging	9.4 Exceptional 1,000 reviews	View
Uncommoner Hotel by Reverie Boutique Collection	9.2 Wonderful 360 reviews	View
The Cove at Yarmouth by Westgate Resorts	9.2 Wonderful 269 reviews	View

Top Main Street Hyannis Hotel Reviews

Uncommoner Hotel by Reverie Boutique Collection

8/10 Good

"You guys need more of your guys need more options for a breakfast and dinner"

Cape Sands Inn

8/10 Good

"Comfortable room. Great view. The adjoining room door did not lock."

Sunbird Cape Cod Resort

10/10 Excellent

"Excellent stay. Very clean. Great staff. Convenient to everything. Would definitely stay again."

Cape Cod Harbor House Inn

10/10 Excellent

"Room was clean, staff particularly helpful, parking on site, convenient to restaurants , beach , and stores. Would definitely stay here again."

Hyannis Travel Inn

10/10 Excellent

"The staff were friendly and helpful. Great location. I would definitely stay again!"

Ocean Street Inn on Hyannis Harbor

10/10 Excellent

"Was a great experience!"

Doubletree by Hilton Cape Cod - Hyannis

10/10 Excellent

"Nice hotel in a convenient location, especially since we had a car and were traveling around Cape Cod. The rooms were spacious, clean, and nicely updated. Free parking was an added bonus. Overall, a comfortable and convenient place to stay while exploring the Cape."

Other attractions near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

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Cape Cod Maritime Museum

9.0/10 (16 reviews)

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.

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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)

After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.

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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)

Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.

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Hyannis Armory

Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area.

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Hyannis Youth & Community Center

8.2/10 (22 reviews)

You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area.

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Zion Union Heritage Museum

6.0/10 (1 review)

You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants.

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Commotion Charters

6.0/10 (3 reviews)

Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area.

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Frequently asked questions

What's the area like around Main Street Hyannis?

Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 197 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Main Street Hyannis?

Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Plaza Hotel.

How many hotels can I expect to find near Main Street Hyannis?

Expedia has 197 hotels and other accommodation options within a mile from Main Street Hyannis.

If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?

Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.

What can I see and do near Main Street Hyannis?

John F. Kennedy Hyannis Museum, Centerville Historical Museum and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.

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Things to do in Cape Cod

Hotels near Main Street Hyannis

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Main Street Hyannis hotels

1. Hyannis Travel Inn

2. Sea Street Inn

3. Anchor In Distinctive Waterfront Lodging

4. Uncommoner Hotel by Reverie Boutique Collection

5. The Cove at Yarmouth by Westgate Resorts

6. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

7. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

8. Hampton Inn & Suites Cape Cod-West Yarmouth

9. Bayside Resort Hotel

10. Courtyard By Marriott Cape Cod Hyannis

11. Courtyard Resort

12. Doubletree by Hilton Cape Cod - Hyannis

13. Cape Sands Inn

14. Hyannis Harbor Hotel

15. Holiday Inn Hyannis by IHG

16. Comfort Inn Hyannis - Cape Cod

17. Sunbird Cape Cod Resort

18. Hyannis Host Inn

19. Americas Best Value Inn & Suites Hyannis Cape Cod

20. Sunbird ANNEX Resort

Compare popular hotels close to Main Street Hyannis

Top Main Street Hyannis Hotel Reviews

Uncommoner Hotel by Reverie Boutique Collection

Cape Sands Inn

Sunbird Cape Cod Resort

Cape Cod Harbor House Inn

Hyannis Travel Inn

Ocean Street Inn on Hyannis Harbor

Doubletree by Hilton Cape Cod - Hyannis

Other attractions near Main Street Hyannis

John F. Kennedy Hyannis Museum

Cape Cod Maritime Museum

St. Francis Xavier Church

John F. Kennedy Memorial

Hyannis Armory

Hyannis Youth & Community Center

Zion Union Heritage Museum

Commotion Charters

Frequently asked questions

Explore a world of travel with Expedia