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Our top choices for Main Street Hyannis hotels

Sea Street Inn
Sea Street Inn1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
The price is S$334
includes taxes & fees
22 Feb - 23 Feb

Anchor In Distinctive Waterfront Lodging
Anchor In Distinctive Waterfront Lodging0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,002 reviews)
The price is S$208
includes taxes & fees
23 Feb - 24 Feb

Uncommoner Hotel by Reverie Boutique Collection
Uncommoner Hotel by Reverie Boutique Collection1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (114 reviews)
The price is S$177
includes taxes & fees
27 Feb - 28 Feb

Hampton Inn & Suites Cape Cod-West Yarmouth
Hampton Inn & Suites Cape Cod-West Yarmouth1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
The price is S$153
includes taxes & fees
15 Mar - 16 Mar

Bayside Resort Hotel
Bayside Resort Hotel2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,552 reviews)
The price is S$150
includes taxes & fees
4 Mar - 5 Mar

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Fairfield Inn & Suites by Marriott Cape Cod Hyannis2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (679 reviews)
The price is S$178
includes taxes & fees
4 Mar - 5 Mar

Courtyard Resort
Courtyard Resort0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (59 reviews)
The price is S$158
includes taxes & fees
4 Mar - 5 Mar

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Heritage House Inn on Cape Cod, an Ascend Collection Hotel0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
The price is S$184
includes taxes & fees
8 Mar - 9 Mar

Doubletree by Hilton Cape Cod - Hyannis
Doubletree by Hilton Cape Cod - Hyannis0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (891 reviews)
The price is S$186
includes taxes & fees
21 Mar - 22 Mar

Cape Sands Inn
Cape Sands Inn1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,023 reviews)
The price is S$108
includes taxes & fees
22 Feb - 23 Feb

Comfort Inn Hyannis - Cape Cod
Comfort Inn Hyannis - Cape Cod0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,004 reviews)
The price is S$135
includes taxes & fees
19 Mar - 20 Mar

Hyannis Harbor Hotel
Hyannis Harbor Hotel0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,003 reviews)
The price is S$211
includes taxes & fees
22 Feb - 23 Feb

Holiday Inn Hyannis by IHG
Holiday Inn Hyannis by IHG2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (989 reviews)
The price is S$165
includes taxes & fees
25 Feb - 26 Feb

Sea Breeze Inn
Sea Breeze Inn1.8 km from Main Street Hyannis
7.8 out of 10, Good, (193 reviews)
The price is S$129
includes taxes & fees
22 Feb - 23 Feb

Hyannis Plaza Hotel
Hyannis Plaza Hotel0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,000 reviews)
The price is S$130
includes taxes & fees
2 Mar - 3 Mar

Sal's Place
Sal's Place2.5 km from Main Street Hyannis
The price is S$732
includes taxes & fees
22 Feb - 23 Feb

The Village Inn Cape Cod
The Village Inn Cape Cod6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (224 reviews)
The price is S$297
includes taxes & fees
22 Feb - 23 Feb

Inn on Main
Inn on Main6.4 km from Main Street Hyannis
10.0 out of 10, Exceptional, (74 reviews)
The price is S$358
includes taxes & fees
26 Feb - 27 Feb

The Escape Inn
The Escape Inn7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (672 reviews)
The price is S$117
includes taxes & fees
23 Feb - 24 Feb

Margaritaville Resort Cape Cod
Margaritaville Resort Cape Cod3.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (461 reviews)
The price is S$254
includes taxes & fees
23 Feb - 24 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Main Street Hyannis
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Sea Street Inn | 9.8 Exceptional 45 reviews | View | ||||||
![]() Anchor In Distinctive Waterfront Lodging | 9.4 Exceptional 1,002 reviews | View | ||||||
![]() Uncommoner Hotel by Reverie Boutique Collection | 9.4 Exceptional 114 reviews | View | ||||||
![]() Hampton Inn & Suites Cape Cod-West Yarmouth | 8.8 Excellent 1,000 reviews | View | ||||||
![]() Bayside Resort Hotel | 8.8 Excellent 1,552 reviews | View |
Top Main Street Hyannis Hotel Reviews

Margaritaville Resort Cape Cod
10/10 Excellent
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