Hotels in Medical Center District

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center District hotels

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,323 reviews)
"Enjoyed breakfast and dinner options"
United States
Pete
The price is S$136
includes taxes & fees
27 May - 28 May
Drury Inn & Suites San Antonio Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,061 reviews)
"The hotel’s location is great. The reception staff was welcoming and friendly, and the rooms are always clean. "
United States
Maria
The price is S$154
includes taxes & fees
29 May - 30 May
San Antonio Marriott Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,355 reviews)
"Great stay"
United States
Marques
The price is S$134
includes taxes & fees
24 May - 25 May
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,001 reviews)
"Was a great stay. "
United States
Sunanda
The price is S$129
includes taxes & fees
31 May - 1 Jun
Fairfield Inn & Suites by Marriott San Antonio Medical Center

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (235 reviews)
"I appropriated their accommodation to give us a bottom floor room (back problems)"
United States
Tonya
The price is S$77
includes taxes & fees
7 Jun - 8 Jun
OYO Inn & Suites Medical Center San Antonio

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Is a good place with good parking and service costumer"
United States
Raymond
The price is S$99
includes taxes & fees
7 Jun - 8 Jun
Park Inn by Radisson

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,000 reviews)
"Clean, helpful staff. "
United States
Edna
The price is S$140
includes taxes & fees
6 Jun - 7 Jun
Courtyard by Marriott Medical Center San Antonio

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (293 reviews)
"Yes .staff really nice "
United States
jamar
The price is S$67
includes taxes & fees
22 Jun - 23 Jun
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
7.0 out of 10, Good, (1,004 reviews)
"Great breakfast!"
United States
Eric Allan
The price is S$90
includes taxes & fees
28 May - 29 May
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (291 reviews)
"Nice place I’m grateful for the price"
United States
Angelo
The price is S$70
includes taxes & fees
1 Jun - 2 Jun
Studio 6 San Antonio, Tx - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (533 reviews)
"Ok place to stay a night or 2 Denny's and mc Donald's are walking distance , rooms are clean beds are ok not sure if a female traveling alone would feel safe , there's no breakfast, "
United States
Santiago
The price is S$60
includes taxes & fees
1 Jun - 2 Jun
Flex Studios

Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (902 reviews)
"It was an amazing stay "
United States
Cordale
The price is S$78
includes taxes & fees
31 May - 1 Jun
Studio 6 Extended Stay - San Antonio, TX - Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
The price is S$69
includes taxes & fees
26 May - 27 May
Motel 6 San Antonio, TX - Northwest Medical Center

Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (1,662 reviews)
"Nice place to stay "
United States
Elizabeth
The price is S$142
includes taxes & fees
8 Jun - 9 Jun
Drury Inn & Suites Near La Cantera Parkway

La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,004 reviews)
"Hotel was decent - had all the amenities i needed. I’d stay here again if I’m ever in town again."
United States
Meghan
The price is S$126
includes taxes & fees
25 May - 26 May
La Quinta Inn & Suites by Wyndham San Antonio Northwest

Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
9.0 out of 10, Wonderful, (414 reviews)
"Clean hotel and friendly staff! I would stay there again. "
United States
Jacob
The price is S$95
includes taxes & fees
9 Jun - 10 Jun
Spark by Hilton San Antonio Dominion

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,005 reviews)
"Very clean, really enjoyed our stay in this place"
United States
Frederick Magtibay
The price is S$108
includes taxes & fees
7 Jun - 8 Jun
Best Western Garden Inn

Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (892 reviews)
"Excellent stay! "
United States
Roxanne
The price is S$111
includes taxes & fees
16 Jun - 17 Jun
Hampton Inn & Suites Schertz

Comfort Inn & Suites Texas Hill Country

Comfort Inn & Suites Texas Hill Country
2.5 star property
33.8 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Nice hotel."
United Kingdom
susan
The price is S$135
includes taxes & fees
31 May - 1 Jun
Comfort Inn & Suites Texas Hill Country

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.0 out of 10, Wonderful, (290 reviews)
"Smooth check in, the front desk staff were friendly. The room was clean, had good amenities and was spacious."
United States
Brittany
The price is S$127
includes taxes & fees
25 May - 26 May
Extended Stay America Premier Suites - San Antonio - Schertz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,323 reviews
View
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,001 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,061 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,000 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,355 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include San Antonio Marriott Northwest Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 136 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

Explore a world of travel with Expedia