Medical Center District

San Antonio

River walk in San Antonio
River walk in San Antonio
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Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is S$133 per night from 26 Feb to 27 Feb
S$133
26 Feb - 27 Feb
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,204 reviews)
The staff was very friendly and helpful. I've been to San Antonio but I enjoyed their welcoming disposition

Reviewed on 24 Feb, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is S$152 per night from 21 Mar to 22 Mar
S$152
21 Mar - 22 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,019 reviews)
We couldn't get the AC to work correctly. We sweated throughout the night. Not good.

Reviewed on 23 Feb, 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
The price is S$94 per night from 22 Mar to 23 Mar
S$94
22 Mar - 23 Mar
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular attractions ...
7.2/10 Good! (1,000 reviews)
Good price. Good location. Not fancy

Reviewed on 23 Feb, 2026

Park Inn by Radisson
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham San Antonio TX
The price is S$146 per night from 3 Mar to 4 Mar
S$146
3 Mar - 4 Mar
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,575 reviews)
than 1 person checking in as everyoneTook 45 minutes. Did not tell us room service was request only? Why do we have to request for a stay longer only

Reviewed on 25 Feb, 2026

Crockett Hotel
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is S$226 per night from 8 Mar to 9 Mar
S$226
8 Mar - 9 Mar
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (2,509 reviews)
The stay was nice. It was a beautiful hotel in a great location. The staff was friendly. We did not receive the VIP promotional upgrades or the bottle of wine. Although we did get a small upgrade with a view of the river instead of the city, I had to ask for it by explaining the VIP status for Expedia ...

Reviewed on 25 Feb, 2026

Hotel Valencia Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
The price is S$145 per night from 1 Mar to 2 Mar
S$145
1 Mar - 2 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (3,894 reviews)
Clean room, great customer service, good breakfast.

Reviewed on 25 Feb, 2026

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Northwest Side
Sam's Burger Joint

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
One of the coolest bars in San Antonio. Definitely check it out.

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District