Medical Center District
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio Zoo Any Day Ticket
S$38
per adult
96% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
S$231
per adult
100% of travellers recommend
Dining at Hard Rock Cafe San Antonio
S$52
per traveller
74% of travellers recommend
San Antonio Small Group Premium Night Tour
S$146
per adult
92% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
S$23
per adult
100% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is S$136 per night from 13 Jul to 14 Jul
S$136
13 Jul - 14 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,492 reviews)
"Breakfast was good, clean, nice staff."
Reviewed on 10 Jul, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is S$168 per night from 26 Jul to 27 Jul
S$168
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,120 reviews)
"lRicky was great at the front desk and room service was excellent!"
Reviewed on 12 Jul, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is S$137 per night from 9 Aug to 10 Aug
S$137
9 Aug - 10 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,391 reviews)
"Went there to use the pool for the weekend during cold weather. The pool.was closed. I wish it had posted on the website it was being remodeled and was out of service..I wouldn't have stayed there. Other than that, it was a nice hotel and good service."
Reviewed on 12 Jul, 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is S$136 per night from 7 Aug to 8 Aug
S$136
7 Aug - 8 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,016 reviews)
"Most of the staff were great except the desk clerk onThursday evening. She was quite rude even though I only asked for towels. She made me feels as if I was bothering her. All the other desk clerks were amazing! They were friendly and helpful. Even the maintenance man had superior customer ..."
Reviewed on 11 Jul, 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is S$226 per night from 8 Aug to 9 Aug
S$226
8 Aug - 9 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,910 reviews)
"We’ve stated here before, gives direct access to the Riverwalk, pool on roof nice with great view at night, hotel gives direct access to the Riverwalk. Easy valet and used our car multiple times during stay. Saved money by eating the complimentary meals in morning and evening!"
Reviewed on 12 Jul, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is S$131 per night from 14 Jul to 15 Jul
S$131
14 Jul - 15 Jul
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,500 reviews)
"The staff were very nice and accommodating. The Hotel lobby and Food areas are very nice, but even with renovations the rooms are old, but clean. Could hear people in the next rooms and it sounded like kids were jumping off the beds up stairs for most of the night. Not quite sure if the higher price ..."
Reviewed on 11 Jul, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from San Antonio River to Alamo – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.
