𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Mill Creek (2026)

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Our top choices for Mill Creek hotels

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

1. The Riverview

Cape Girardeau

Alyssa

S$150

includes taxes & fees

30 Sept - 1 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

S$144

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

3. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

S$181

includes taxes & fees

8 Oct - 9 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

4. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

S$104

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

S$147

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

S$146

includes taxes & fees

4 Oct - 5 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

7. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

S$152

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

8. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

S$130

includes taxes & fees

12 Oct - 13 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

9. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

S$86

includes taxes & fees

11 Oct - 12 Oct

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel room with a bed, a TV, a desk, and a chair.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

10. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

S$130

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

11. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

S$112

includes taxes & fees

29 Sept - 30 Sept

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

A stone building with a patio area, string lights, and outdoor seating.

12. Makanda Inn

Makanda

Michele

S$355

includes taxes & fees

30 Sept - 1 Oct

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Top Mill Creek Hotel Reviews

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent

"Staff were so friendly. Newer hotel with spacious rooms. Nice breakfast."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Staff was kind and courteous, Very clean hotel , breakfast was excellent. We came for SEMO daily weekend and we had a great experience at this hotel . We would love to stay here again when we attend more SEMO events . Thank you !"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"The staff is so friendly and helpful! They’re the gems of the hotel!"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Quality Inn Cape Girardeau North

8/10 Good

"No complaints"

Makanda Inn

10/10 Excellent

"This was a unique and very enjoyable visit. We enjoyed the site as it sits in the woods. The birds of the area were plentiful and great in the morning. The room was great with a marvelous bathroom. Comfortable bed. The breakfast we had there was excellent. A wonderful choice."

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

More cheap stays in Mill Creek

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

S$86

11 Oct - 12 Oct

includes taxes & fees

7/10 Good! (800 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

S$104

4 Oct - 5 Oct

includes taxes & fees

9.2/10 Wonderful! (1,005 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

S$130

11 Oct - 12 Oct

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

S$147

4 Oct - 5 Oct

includes taxes & fees

9.4/10 Exceptional! (1,003 reviews)

Hampton Inn Cape Girardeau I 55 East

207 S Mt Auburn Rd Cape Girardeau MO

S$152

4 Oct - 5 Oct

includes taxes & fees

9.6/10 Exceptional! (849 reviews)

Hotel 7 Inn Anna

100 Richview Dr Anna IL

Get rates

6.6/10 (244 reviews)

Frequently asked questions

Where is the best place to stay in Mill Creek?

Drury Plaza Hotel Cape Girardeau Conference Center, located 18.1 mi (29.2 km) from the heart of Mill Creek, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Mill Creek.

If I need to cancel my hotel reservation in Mill Creek, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Mill Creek.

What's it like to stay in Mill Creek?

Those travelling to Mill Creek will definitely enjoy the sights to see and things to do. There are 171 hotels and other accommodation options in the surrounding area. Find out more about Mill Creek.

What should I do while I'm visiting Mill Creek?

Places to visit in the wider area include Trail of Tears State Park, Century Casino & Hotel Cape Girardeau and Hunter Valley Winery. You'll also find Anna City Park and Lower Cache River Access Area in the area. Take a look at what more there is to see and do in Expedia's Mill Creek guide.

What's the weather like in Mill Creek?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Mill Creek is 1431 mm.

Mill Creek Hotels from S$86

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Mill Creek

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mill Creek hotels

1. The Riverview

2. Drury Plaza Hotel Cape Girardeau Conference Center

3. Courtyard by Marriott Cape Girardeau Downtown

4. Pear Tree Inn Cape Girardeau West

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

6. Fairfield Inn & Suites by Marriott Cape Girardeau

7. Hampton Inn Cape Girardeau I 55 East

8. Drury Inn & Suites Cape Girardeau

9. Quality Inn Cape Girardeau North

10. Candlewood Suites Cape Girardeau by IHG

11. Town House Inn Cape Giradreau

12. Makanda Inn

Top Mill Creek Hotel Reviews

Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Pear Tree Inn Cape Girardeau West

Courtyard by Marriott Cape Girardeau Downtown

Quality Inn Cape Girardeau North

Makanda Inn

Town House Inn Cape Giradreau

More cheap stays in Mill Creek

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Cape Girardeau I 55 East

Hotel 7 Inn Anna

Frequently asked questions

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