Hotels near Mission Hope Cancer Center

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Tonight
19 Dec - 20 Dec
Tomorrow
20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Mission Hope Cancer Center hotels

Premium bedding, down duvets, individually decorated
Hotel Avanti

Hotel Avanti

Hotel Avanti
2.5 star property
2.3 km from Mission Hope Cancer Center
9.0 out of 10, Wonderful, (281)
"The rooms were surprisingly nice. "
United States
mario
The price is S$121
includes taxes & fees
21 Dec - 22 Dec
Hotel Avanti
Restaurant
Best Western Plus Big America

Best Western Plus Big America

Best Western Plus Big America
2.5 star property
2.8 km from Mission Hope Cancer Center
8.8 out of 10, Excellent, (1004)
"great place - clean n comfy beds "
United States
Nancy
The price is S$158
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Big America
Exterior
Historic Santa Maria Inn

Historic Santa Maria Inn

Historic Santa Maria Inn
3.5 star property
2.2 km from Mission Hope Cancer Center
8.4 out of 10, Very good, (1856)
"Nice place to stay "
United States
octaviano
The price is S$113
includes taxes & fees
28 Dec - 29 Dec
Historic Santa Maria Inn
Desk, free WiFi
Villa Motel

Villa Motel

Villa Motel
2.0 star property
2.4 km from Mission Hope Cancer Center
8.0 out of 10, Very good, (174)
"Staff was very friendly "
United States
erika
The price is S$99
includes taxes & fees
24 Dec - 25 Dec
Villa Motel
Reception
ECONOMY INN

ECONOMY INN

ECONOMY INN
2.5 star property
2.1 km from Mission Hope Cancer Center
8.0 out of 10, Very good, (72)
"Decent hotel for the price"
United States
ydalid
The price is S$90
includes taxes & fees
23 Dec - 24 Dec
ECONOMY INN
Premium bedding, in-room safe, blackout curtains, iron/ironing board
Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria
2.0 star property
2.9 km from Mission Hope Cancer Center
7.8 out of 10, Good, (1000)
"Great establishment and surrounding neighborhood. "
United States
Julio
The price is S$143
includes taxes & fees
30 Dec - 31 Dec
Travelodge by Wyndham Santa Maria
Desk, iron/ironing board, free cots/infant beds, free WiFi
Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria
2.0 star property
0.8 km from Mission Hope Cancer Center
6.8 out of 10, (1000)
"Room was clean staff was nice. "
United States
Kimberly Dawn
The price is S$104
includes taxes & fees
24 Dec - 25 Dec
Days Inn by Wyndham Santa Maria
View from property
Buckboard Motel

Buckboard Motel

Buckboard Motel
2.5 star property
3 km from Mission Hope Cancer Center
6.8 out of 10, (71)
"Excellent place to rest excellent price "
United States
Carlos
The price is S$91
includes taxes & fees
30 Dec - 31 Dec
Buckboard Motel
Outdoor pool
Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South
2.0 star property
0.5 km from Mission Hope Cancer Center
5.8 out of 10, (510)
"Room was nice and the owner and staff were helpful and kind."
United States
Jason
The price is S$111
includes taxes & fees
21 Dec - 22 Dec
Motel 6 Santa Maria, CA - South
Free daily buffet breakfast
Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria
2.5 star property
3.7 km from Mission Hope Cancer Center
9.4 out of 10, Exceptional, (1004)
"Breakfast very good, Parkin field safe ,the room very clean"
United States
Hugo
The price is S$173
includes taxes & fees
4 Jan - 5 Jan, 2026
Hampton Inn & Suites Santa Maria
Free daily continental breakfast
Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (725)
"Clean room and great staff and service! "
United States
Ruby
The price is S$163
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott Santa Maria
Restaurant
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria
3.0 star property
3.5 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (38)
"Friendly staff and nice hotel."
United States
Elisa
The price is S$148
includes taxes & fees
9 Jan - 10 Jan, 2026
Homewood Suites by Hilton Santa Maria
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1000)
"Clean room . Great stay"
United States
Derek
The price is S$138
includes taxes & fees
4 Jan - 5 Jan, 2026
Candlewood Suites Santa Maria by IHG
Exterior
Solaire Inn & Suites

Solaire Inn & Suites

Solaire Inn & Suites
2.5 star property
3.6 km from Mission Hope Cancer Center
8.2 out of 10, Very good, (1001)
"Clean Staff very helpful "
United States
Sally
The price is S$87
includes taxes & fees
25 Dec - 26 Dec
Solaire Inn & Suites
Lobby
Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North
2.0 star property
3.4 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1001)
"Yes, the staff was courteous and the room although bare bones was clean."
United States
Richard
The price is S$72
includes taxes & fees
28 Dec - 29 Dec
Motel 6 Santa Maria, CA - North
Terrace/patio
Wine Stone Inn

Wine Stone Inn

Wine Stone Inn
5.0 star property
10.2 km from Mission Hope Cancer Center
9.8 out of 10, Exceptional, (600)
"Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. "
United States
shannon
The price is S$241
includes taxes & fees
4 Jan - 5 Jan, 2026
Wine Stone Inn
Desk, blackout curtains, iron/ironing board, free WiFi
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

Radisson Hotel Santa Maria
3.5 star property
6.8 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1327)
"Staff was great . They were very welcoming made the stay comfortable "
United States
Luis
The price is S$143
includes taxes & fees
21 Dec - 22 Dec
Radisson Hotel Santa Maria
Desk, free WiFi, bed sheets, wheelchair access
Colonial Motel

Colonial Motel

Colonial Motel
2.0 star property
3.4 km from Mission Hope Cancer Center
6.4 out of 10, (164)
"I recomendar this place "
United States
Everarda
The price is S$123
includes taxes & fees
28 Dec - 29 Dec
Colonial Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Hope Cancer Center Hotel Reviews

Historic Santa Maria Inn

Historic Santa Maria Inn

10/10 Excellent
"Beautiful historic hotel. Stayed in the towers. Been there many times visiting family. I've gone on October, they decorate the bottle beautifully went on December and it was decorated for Christmas, just beautiful. Rooms are large and clean. Staff was great. "
Jonene 2-night trip
Posted 2 days ago
Historic Santa Maria Inn

Hotels near other Mission Hope Cancer Center attractions

Pacific Conservatory Theatre

You can enjoy a show at Pacific Conservatory Theatre on your trip to Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Simas Park

After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 6 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveller data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Another good option is Hampton Inn & Suites Santa Maria, located 2.3 mi (3.7 km) away.
How many hotels will I be able to find near Mission Hope Cancer Center?
Expedia has 6 hotels and other accommodation options within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Mission Hope Cancer Center.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Santa Maria Valley Discovery Museum, Rancho Bowl and Santa Maria Fairpark are fun stops for the whole family while you're in town.