Hotels in Murex Lakes

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Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Murex Lakes hotels

Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
14.9 km from Murex Lakes
9.0 out of 10, Wonderful, (1007)
"Clean rooms, friendly staff, so much to do there and nearby "
United States
Lisa R
The price is S$232
includes taxes & fees
17 Dec - 18 Dec
Lani Kai Beachfront Resort
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
17.6 km from Murex Lakes
9.4 out of 10, Exceptional, (1000)
"Great rooms, good staff"
United States
Dedan
The price is S$140
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
15.6 km from Murex Lakes
8.8 out of 10, Excellent, (1003)
"Great Place to Stay!"
United States
JUDY
The price is S$138
includes taxes & fees
14 Dec - 15 Dec
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 5.3 km from Murex Lakes
9.2 out of 10, Wonderful, (1463)
"Courteous staff, easy parking, close beach"
United States
Jenna
The price is S$327
includes taxes & fees
17 Dec - 18 Dec
Sanibel Island Beach Resort
Exterior
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
29.2 km from Murex Lakes
8.8 out of 10, Excellent, (699)
"Amazing place!"
United States
Douglas
The price is S$142
includes taxes & fees
14 Dec - 15 Dec
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
14.2 km from Murex Lakes
8.6 out of 10, Excellent, (1001)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
The price is S$137
includes taxes & fees
18 Dec - 19 Dec
Residence Inn by Marriott Fort Myers Sanibel
2 outdoor pools
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
14.7 km from Murex Lakes
8.6 out of 10, Excellent, (1567)
"Great location… the tiki bar was the best bar on the beach.. not just on weekends, allllllll week "
United States
Adam
The Lighthouse Resort Inn & Suites
Reception
Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
27.6 km from Murex Lakes
7.6 out of 10, Good, (1115)
"Everything was awesome, the location was good, staff was nice, and room was way better than we expected! Would definitely stay here again! "
United States
Josie
The price is S$93
includes taxes & fees
14 Dec - 15 Dec
Americas Best Value Inn Ft. Myers
Lobby
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
28.7 km from Murex Lakes
7.6 out of 10, Good, (199)
"Microwave made an explosion when tried to use it. The rest amazing"
United States
Alain
The price is S$107
includes taxes & fees
18 Dec - 19 Dec
Quality Inn Fort Myers Cape Coral
Exterior
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
14.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1698)
"Great place "
United States
Debra Sue
The price is S$318
includes taxes & fees
17 Dec - 18 Dec
Margaritaville Beach Resort Fort Myers
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
25.7 km from Murex Lakes
8.8 out of 10, Excellent, (1009)
"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "
United States
Aleksandar
The price is S$153
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn Ft Myers
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
21.2 km from Murex Lakes
9.4 out of 10, Exceptional, (1033)
"Hotel was very clean and the breakfast had a great variety."
United States
Lynn
The price is S$163
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Outdoor pool, open 7:30 AM to 9:30 PM, free pool cabanas, pool loungers
Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
16.2 km from Murex Lakes
8.6 out of 10, Excellent, (905)
"Wonderful stay at the property. It was hard to leave."
United States
Aaron
Latitude 26 Waterfront Resort & Marina
Outdoor pool, open 8:00 AM to 10:00 PM, pool cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
15.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1002)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is S$260
includes taxes & fees
21 Dec - 22 Dec
The Westin Cape Coral Resort At Marina Village
Lobby lounge
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
25.7 km from Murex Lakes
8.6 out of 10, Excellent, (782)
"Clean room and very nice staff "
United States
Michael
The price is S$128
includes taxes & fees
19 Dec - 20 Dec
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Exterior
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
20.2 km from Murex Lakes
8.6 out of 10, Excellent, (1002)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is S$137
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Exterior
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
13.9 km from Murex Lakes
9.4 out of 10, Exceptional, (1192)
"Friendly staff, fun kid events "
United States
Payge
The price is S$375
includes taxes & fees
11 Jan - 12 Jan, 2026
Pink Shell Beach Resort and Marina
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
10.9 km from Murex Lakes
8.4 out of 10, Very good, (1003)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is S$319
includes taxes & fees
15 Dec - 16 Dec
Marriott Sanibel Harbour Resort & Spa
Bar (on property)
Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
14.8 km from Murex Lakes
9.2 out of 10, Wonderful, (1002)
"Was great location "
United States
Jose
The price is S$171
includes taxes & fees
14 Dec - 15 Dec
Matanzas Inn Bayside Resort and Marina
Outdoor pool, pool loungers
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
26.6 km from Murex Lakes
8.8 out of 10, Excellent, (1004)
"Liked the evening cookies, rooms were clean, would have liked bathtub and hotter water the first am but overall great location "
United States
NINA
The price is S$188
includes taxes & fees
18 Dec - 19 Dec
Doubletree by Hilton Fort Myers at Bell Tower Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Murex Lakes

Find the best Murex Lakes areas for the activities you enjoy most.
Fort Myers showing a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"Everything was great. Highly recommend. "
Irene 3-night trip
Posted 2 days ago
Lani Kai Beachfront Resort

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Frequently asked questions

What's it like in Murex Lakes?
You'll be sure to have fun exploring Sanibel's Murex Lakes neighbourhood.
How many hotels can I expect to find in Murex Lakes?
If you're searching for places to stay in Sanibel, choose from one of Expedia's 16 hotels and other accommodation options in Murex Lakes.
If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Murex Lakes.
What is there to do around this Sanibel neighbourhood?
Sanibel Captiva Conservation Foundation, Bailey - Matthews Shell Museum and Sanibel Island Southern Beach are just a few of the places to visit in and around Murex Lakes. When you're sightseeing in Sanibel, Sanibel Historical Museum and Village and Sanibel Historical Village and Museum are also worth a stop.