Mytilene Holidays

Photo by Hecktic Travels

  • Plan, book, travel with confidence

  • Better together

    Save up to S$134 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.
Book now

Mytilene Beach Holiday

Get set to live out those beachy daydreams on your upcoming Mytilene holiday. Set off on a lovely stroll, take in the sweeping ocean views and collect unique seashells during your trip to Mytilene. Located just 10 kilometres from the city centre, Thermi Beach is the place to be for many travellers. Look through our Mytilene packages and watch your travel budget stretch further!

Things You Should Know About Mytilene

  • If you want that beachside lifestyle, have a look at our Mytilene beach hotels. Beautiful water views and refreshing sea air — what more could anyone want?
  • Take a look at Sunrise Resort Hotel and Elysion Hotel. These hotels might just be perfect for your holiday in Mytilene.
  • There are plenty of activities that keep the 28,300 or so residents of Mytilene busy. A quick look at our Mytilene things to do page will let you in on everything this place has to offer.
  • If you're searching for things to do while you're in town, add University of the Aegean, Thermi Beach and Port of Mytilene to your travel schedule. Also, take a look at our Mytilene holiday deals to save money on your experiences, hotels and more.

Top hotels in Mytilene

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

4 out of 5
7, Skra str, Hatzidimitriou Park Lesvos
Fully refundableReserve now, pay when you stay
9.6/10 Exceptional! (160 reviews)
The room was impeccable. The staff were courteous enough to let us check in a few hours early after a long trip.

Reviewed on 29 Jan, 2026

Get rates
Theofilos Paradise Boutique Hotel
The Loriet

The Loriet

4 out of 5
Vareia, Mitilene Lesvos Lesvos Island
Fully refundableReserve now, pay when you stay
The price is S$85 per night from 3 Mar to 4 Mar
S$85
3 Mar - 4 Mar
includes taxes & fees
8.4/10 Very Good! (78 reviews)
Temizlik, kaliteli hizmet, çözüm odakkı müşteri iletişimi, vb.

Reviewed on 19 Nov, 2025

The Loriet
Heliotrope Hotels

Heliotrope Hotels

4 out of 5
Varia Lesvos Lesvos Island
Fully refundableReserve now, pay when you stay
The price is S$124 per night from 3 Mar to 4 Mar
S$124
3 Mar - 4 Mar
includes taxes & fees
Heliotrope Hotels
See all 167 properties in Mytilene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.