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Hotels in Medical Center District

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Check prices for these dates

This weekend
21 Aug - 23 Aug
Next weekend
28 Aug - 30 Aug

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Our top choices for Medical Center District hotels

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

1. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,010 reviews)
"Very clean facility, pool was in business a d it was nice, peaceful and quiet."
United States
Melissa
The price is S$134
includes taxes & fees
28 Aug - 29 Aug
Courtyard by Marriott Medical Center San Antonio
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

2. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,421 reviews)
"Amazaing stay friendly staff!"
United States
Melissa
The price is S$135
includes taxes & fees
26 Aug - 27 Aug
Drury Inn & Suites San Antonio Northwest Medical Center
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,599 reviews)
"Great location and very clean/nice."
United States
Melissa
The price is S$133
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

4. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,052 reviews)
"Great Stay!"
United States
Matthew
The price is S$128
includes taxes & fees
6 Sept - 7 Sept
Fairfield Inn & Suites by Marriott San Antonio Medical Center
A modern kitchen with a large window, wooden counter, and two bar stools.

5. Park Inn by Radisson, Medical Center

Park Inn by Radisson, Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (1,003 reviews)
"Room was very clean, walking distance from hospitals. Ample parking"
United States
Gloria
The price is S$95
includes taxes & fees
9 Sept - 10 Sept
Park Inn by Radisson, Medical Center
A spacious lobby with a central staircase, seating area, and large windows.

6. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,151 reviews)
"Great hotel"
United States
Mario
The price is S$163
includes taxes & fees
20 Sept - 21 Sept
San Antonio Marriott Northwest Medical Center
A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

7. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (245 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is S$87
includes taxes & fees
20 Sept - 21 Sept
OYO Inn & Suites Medical Center San Antonio
A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

8. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (309 reviews)
"👌"
United States
Gloria
The price is S$84
includes taxes & fees
22 Aug - 23 Aug
Atria Inn & Suites
A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

9. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (356 reviews)
"Good staff great room for the price Quiet area"
United States
RUDY AGUIRRE
The price is S$70
includes taxes & fees
24 Aug - 25 Aug
Studio 6 San Antonio, Tx - Northwest Medical Center
A modern bedroom with a large bed, bedside tables, a desk, and a chair.

10. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"front desk reps very friendly and helpful"
United States
Rachel
The price is S$76
includes taxes & fees
30 Aug - 31 Aug
Motel 6 San Antonio, TX - Northwest Medical Center
A hotel room with two beds, a TV, a desk, and a kitchenette in the background.

11. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (976 reviews)
"Friendly staff, room was cleaned and well kept."
United States
Jose
The price is S$81
includes taxes & fees
21 Aug - 22 Aug
Studio 6 Extended Stay - San Antonio, TX - Medical Center
A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

12. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.2 out of 10, (565 reviews)
"Yes I would stay again"
United States
Jasper
The price is S$60
includes taxes & fees
25 Aug - 26 Aug
Flex Studios
A modern bar area with a central island, bar stools, and a kitchen counter with appliances.

13. Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.7 km from Medical Center District
8.4 out of 10, Very good, (1,025 reviews)
"Clean cold room, welcoming great location"
United States
Daniel
The price is S$141
includes taxes & fees
27 Aug - 28 Aug
Hyatt Place San Antonio-Northwest/Medical Center
A spacious dining area with multiple tables and chairs, a bar area, and a television mounted on the wall.

14. Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.7 km from Medical Center District
8.4 out of 10, Very good, (1,053 reviews)
"Solid property… friendly staff, and great for an overnight business trip"
United States
James
The price is S$137
includes taxes & fees
27 Aug - 28 Aug
Hampton Inn & Suites San Antonio Northwest/Medical Center
A swimming pool with clear blue water, a waterfall feature, and lounge chairs around the pool area.

15. Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
2.5 star property
Northwest Side, 4.3 km from Medical Center District
8.0 out of 10, Very good, (1,226 reviews)
"Rooms were amazing and breakfast was perfect!"
United States
Helena
The price is S$126
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
A hotel with a modern design, featuring a covered parking area and multiple parking spaces.

16. Best Western Medical Center North Inn & Suites Near Six Flags

Best Western Medical Center North Inn & Suites Near Six Flags
2.5 star property
Northwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,603 reviews)
"Breakfast was great"
United States
Gayl
The price is S$99
includes taxes & fees
24 Aug - 25 Aug
Best Western Medical Center North Inn & Suites Near Six Flags
An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

17. Drury Inn & Suites Near La Cantera Parkway

Drury Inn & Suites Near La Cantera Parkway
3.0 star property
La Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (1,919 reviews)
"Love staying here !"
United States
Samantha
The price is S$141
includes taxes & fees
25 Aug - 26 Aug
Drury Inn & Suites Near La Cantera Parkway
A hotel lobby with a reception desk, seating area, and a television.

18. La Quinta Inn & Suites by Wyndham San Antonio Northwest

La Quinta Inn & Suites by Wyndham San Antonio Northwest
3.0 star property
Far West Side, 10.4 km from Medical Center District
8.8 out of 10, Excellent, (1,008 reviews)
"Great room. Very clean."
United States
Rudy
The price is S$125
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn & Suites by Wyndham San Antonio Northwest
A spacious lobby with a modern design, featuring a large seating area with sofas and armchairs, a patterned rug, and a reception desk.

19. Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center
2.5 star property
4.6 km from Medical Center District
7.2 out of 10, Good, (2,234 reviews)
"Great hotel,great staff"
United States
Masumbuko
The price is S$88
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn and Suites Near Medical Center
A modern kitchen with a wooden countertop, a coffee station, and a food display.

20. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
2.5 star property
7.7 km from Medical Center District
8.4 out of 10, Very good, (1,010 reviews)
"Great place"
United States
William
The price is S$101
includes taxes & fees
30 Aug - 31 Aug
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,421 reviews
View
A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,052 reviews
View
A modern bar area with wooden bar counters, black bar stools, and pendant lighting.
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,010 reviews
View
A spacious lobby with a central staircase, seating area, and large windows.
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,151 reviews
View
A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,599 reviews
View

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

A large, abstract sculpture with a flowing design, set against a dramatic sky.
Photo by Sarah C.
Open Photo by Sarah C.

Uptown

If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.

A large, modern building with a blue and white color scheme, featuring a prominent circular window and a 'Welcome' sign.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A nighttime amusement park with roller coasters, a bridge, and a full moon.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Top Medical Center District Hotel Reviews

Hotel Contessa

Hotel Contessa

8/10 Good
"Overall this is a great hotel. The location is fantastic for getting to restaurants and attractions near the riverwalk. Most are within walking distance. You can walk out the back doors and you are standing on the riverwalk. Food at the on site restaurant is okay, nothing special. The food is very overpriced for what you get.The hotel staff were friendly and very helpful. The rooms are a little outdated and could use a refresh."
Jeffrey 3-night trip
Posted 1 hour ago
Hotel Contessa

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Consider a visit to Cinemark San Antonio 16 as part of your Medical Center District travel plans.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include Courtyard by Marriott Medical Center San Antonio and Drury Inn & Suites San Antonio Northwest Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 124 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
Cinemark San Antonio 16 is an attraction you might want to check out while you're in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

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