Otay Mesa
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
Stand up Paddle Board Lesson on The San Diego Bay
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"Very clean room, comfortable beds, and a variety of selections in the breakfast buffet. We had trouble with the TV and staff came right up and assisted and got it up and going. I wish I would have realized how close the Mexico border was, we would have brought our passports to go shopping. There ..."
Reviewed on 2 Sept, 2026
Manchester Grand Hyatt San Diego
"Great and clean place to be"
Reviewed on 2 Sept, 2026
Wyndham San Diego Bayside
Paradise Point Resort & Spa
"Lovely place"
Reviewed on 1 Sept, 2026
The Dana on Mission Bay
"The hotel is old & needs to be upgraded. Especially since it’s right on the bay."
Reviewed on 1 Sept, 2026
Hard Rock Hotel San Diego
"The staff was so nice but there is no clear number to call for things, I had to go down to the front desk to ask for blankets and utensils. The keycard reader for my room kept falling off?? The pool is so tiny and my room didn’t even have a microwave. For as expensive as it is I did expect more. ..."
Reviewed on 2 Sept, 2026
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
