Otay Mesa
San Diego
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's entertainment choices and fascinating museums.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
Crossing Borders: Tijuana Day Trip from San Diego
Stand up Paddle Board Lesson on The San Diego Bay
Top hotels in Otay Mesa
Paradise Point Resort & Spa
everything was so good. loved the pools food and the grounds. already looking to go back..
Reviewed on 5 Mar, 2026
Bay Club Hotel & Marina
Beautiful place for a relaxing getaway
Reviewed on 4 Mar, 2026
Hard Rock Hotel San Diego
Beautiful views, in the heart of gaslamp, clean and wonderful service. Will definitely return.
Reviewed on 4 Mar, 2026
The DEXTRO Little Italy, BW Premier Collection
The staff was SO NICE. R
Reviewed on 4 Mar, 2026
Best Western Seven Seas
I love this hotel! The staff is so kind and efficient! The rooms are clean, the bed is comfy. The rooms are basic and I like it that way! The price is perfect. I will always stay here while in San Diego.
Reviewed on 5 Mar, 2026
Days Inn by Wyndham San Diego Hotel Circle
Everything was great.
Reviewed on 4 Mar, 2026
Other neighbourhoods around Otay Mesa
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
