Otay Mesa
San Diego
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
Tijuana Downtown Self Guided Walking Tour
From Tijuana: Valle de Guadalupe Private Winery Tour
From Tijuana: Valle de Guadalupe Shared Winery Tour
Top hotels in Otay Mesa
Hotel del Coronado, Curio Collection by Hilton
Room was nice, walkability was great. On site amenities made the stay easy traveling with a toddler.
Reviewed on 18 Nov, 2025
Legacy Resort Hotel & Spa
Great food, clean rooms
Reviewed on 25 Nov, 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
Spotless room. Friendly staff
Reviewed on 30 Nov, 2025
Manchester Grand Hyatt San Diego
Great place, need to improve the rooms !
Reviewed on 24 Nov, 2025
Hard Rock Hotel San Diego
Required an accumulated deposit for all the nights there, in advance of the stay. For example, if the deposit for each night was $100 and the stay was 5 nights, $500 was secured. This, on a prepayed hotel room. I had booked this room for an adult child (over 30 years old) as a gift and found this ...
Reviewed on 26 Nov, 2025
The DEXTRO Little Italy, BW Premier Collection
10:/10
Reviewed on 30 Nov, 2025
Other neighbourhoods around Otay Mesa
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Marina District
Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
