Hotels in Otay Mesa

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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,696 reviews)
"Everything was excellent. Very courteous staff. I plan to stay here again when I visit San Diego in the spring."
United States
Sue
The price is S$170
includes taxes & fees
21 Apr - 22 Apr
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,004 reviews)
"The only hotel in otay mesa and overall the service was good"
United States
MARIA
The price is S$143
includes taxes & fees
10 May - 11 May
Quality Suites San Diego Otay Mesa

The Rambler Hotel

The Rambler Hotel
3.0 star property
14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,115 reviews)
"Incredibly cute and comfortable motel! The on-site coffee shop was excellent and the park across the street was so fun to walk/hike! Will definitely be coming back for another stay-cation!"
United States
Cara
The price is S$175
includes taxes & fees
28 Apr - 29 Apr
The Rambler Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,782 reviews)
"Helpful, courteous staff. The suites include 2 queen beds plus a sofa bed perfect for our family. The location is right off the freeway and near many places to eat. "
United States
Sonia
The price is S$213
includes taxes & fees
26 Apr - 27 Apr
Best Western Plus Marina Gateway Hotel

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,001 reviews)
"Room was great, very clean. Staff was so friendly and helpful. Other visitors were great conversation over breakfast. Tons of places to eat walking distance and super close to the beach. For the price it was incredible. Will be returning soon. "
United States
Isabel
The price is S$221
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn & Suites Imperial Beach San Diego

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,255 reviews)
"Super nice, rooms were nice and clean and breakfast was good. There was even homemade salsa."
United States
Patricia
The price is S$177
includes taxes & fees
26 Apr - 27 Apr
Best Western Americana Inn

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,588 reviews)
"The room was nice and clean. The staff was very friendly. Our needs were met. As a landmark, they are located adjacent/behind Denny's. Google Maps sent us around through the back which was the long way."
United States
Rachel
The price is S$142
includes taxes & fees
3 May - 4 May
La Quinta Inn by Wyndham San Diego Chula Vista

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,858 reviews)
"Staff is welcoming and so helpful. Room was very clean, spacious, and the bed was comfortable. The casino downstairs had 3 restaurants and 2 corner delis so getting food was not a problem. Will be coming back."
United States
Maria
The price is S$189
includes taxes & fees
19 Apr - 20 Apr
Sycuan Casino Resort

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
13 km from Otay Mesa
8.2 out of 10, Very good, (1,428 reviews)
"Front desk personnel were very friendly. Check process was smooth and fast. Breakfast was ok, the served Mexican "
United States
Mary
The price is S$142
includes taxes & fees
10 May - 11 May
Comfort Inn Chula Vista San Diego South

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,094 reviews)
"Everything was excellent! The staff was very friendly and helpful! We loved the breakfast set up! If we are ever in the area, we will definitely stay here again!"
United States
ron
The price is S$188
includes taxes & fees
10 May - 11 May
Holiday Inn Express San Diego South - Chula Vista by IHG

Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
13.6 km from Otay Mesa
8.6 out of 10, Excellent, (1,418 reviews)
"The hotel was close to freeway and all the areas we wanted to go. The staff was very pleasant. Rooms were a little smaller than expected and you can hear the people in the next room but great price "
United States
Lucrecia Christine
The price is S$149
includes taxes & fees
10 May - 11 May
Hercor Hotel - Urban Boutique

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (627 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
United States
Daniel
The price is S$264
includes taxes & fees
3 May - 4 May
SpringHill Suites by Marriott Chula Vista Eastlake

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (2,979 reviews)
"The staff were excellent and made my stay very pleasant! I loved my massage and facial too! I will definitely come again!!"
United States
Nicole
The price is S$272
includes taxes & fees
4 May - 5 May
Legacy Resort Hotel & Spa

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,196 reviews)
"We stayed one night due to a delayed flight. The place was clean & tidy, the pool was fantastic. Staff was amazing. Great for a short budget friendly stay. "
United States
Karla
The price is S$174
includes taxes & fees
27 Apr - 28 Apr
Wyndham Garden San Diego Near SeaWorld

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,702 reviews)
"Very friendly staff helped me when I needed a little help with small things. I needed a place to rest and everyone was most kind."
United States
Denise
The price is S$243
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn & Suites San Diego Airport Liberty Station

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,466 reviews)
"Wow! I am so happy we got to stay here. Everything about this place was luxury- while still keeping it at a good budget. The bike rentals were super fun and the staff was AMAZING! Great place to stay! :)"
United States
Mary
The price is S$279
includes taxes & fees
11 May - 12 May
Sheraton San Diego Resort

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
24.4 km from Otay Mesa
9.2 out of 10, Wonderful, (2,092 reviews)
"Great place for families!!"
Canada
Ilijana
The price is S$412
includes taxes & fees
1 May - 2 May
Marriott Marquis San Diego Marina

Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon
3.0 star property
26.3 km from Otay Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Clean room, good food at the Bistro, excellent drinks at the bar. Wonderful service with everyone we came in contact with, especially the young man at the front desk who was working when we checked out at about noon today (12/14). Thank you!"
United States
Adriane
The price is S$219
includes taxes & fees
10 May - 11 May
Courtyard by Marriott San Diego El Cajon

TownePlace Suites by Marriott San Diego Airport/Liberty Station

TownePlace Suites by Marriott San Diego Airport/Liberty Station
3.0 star property
29.3 km from Otay Mesa
9.0 out of 10, Wonderful, (1,002 reviews)
"Great central location to everything we needed. Very close to airport, Seaport Village, Point Loma, Mission Beach, Fashion Valley Mall, etc. Welcoming staff was always available to help. Breakfast had many options. Lobby was an amazing place to hang out. Would definitely stay here again!"
United States
Jacqueline
The price is S$253
includes taxes & fees
26 Apr - 27 Apr
TownePlace Suites by Marriott San Diego Airport/Liberty Station

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,054 reviews)
"Great people. Right next to the freeway, but the back side at least is relatively quiet. Walking distance to old town."
United States
Kevin
The price is S$222
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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