A city skyline with high-rise buildings and a bridge over a body of water.

Hotels in Otay Mesa

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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Otay Mesa hotels

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.4 out of 10, Very good, (1,928 reviews)
"Good staff, very good breakfast, rooms where nice and clean"
United States
Michael
The price is S$189
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
A breakfast station with bread, bagels, waffles, and a coffee machine.

2. Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1,000 reviews)
"clean room nice place to stay"
Mexico
Anonymous traveller
The price is S$150
includes taxes & fees
8 Nov - 9 Nov
Quality Suites San Diego Otay Mesa
A spacious lobby with a fireplace, wooden furniture, and a chandelier.

3. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
8.8 out of 10, Excellent, (1,399 reviews)
"The property was clean, room was serviced every day which was very much appreciated. Breakfast was awesome , staff was friendly"
United States
Lisa Marie
The price is S$152
includes taxes & fees
8 Nov - 9 Nov
Best Western Americana Inn
An outdoor patio area with seating and a bar.

4. Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,048 reviews)
"I was very impressed with this hotel. The rooms were comfortable and modern and the staff was warm and welcoming."
United States
Rosemary
The price is S$251
includes taxes & fees
18 Oct - 19 Oct
Ayres Hotel San Diego South - Chula Vista
A hotel room with two beds, a wooden headboard, a bedside table with a phone, and a wall-mounted light fixture.

5. Rodeway Inn San Diego South San Ysidro Border

Rodeway Inn San Diego South San Ysidro Border
2.0 star property
5.8 km from Otay Mesa
8.0 out of 10, Very good, (280 reviews)
"Great service beautiful hotel"
United States
Guadalupe
The price is S$110
includes taxes & fees
27 Oct - 28 Oct
Rodeway Inn San Diego South San Ysidro Border
A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

6. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
12.9 km from Otay Mesa
8.8 out of 10, Excellent, (1,767 reviews)
"Enjoyed our stay"
United States
Nuwan
The price is S$150
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

7. Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
13 km from Otay Mesa
8.4 out of 10, Very good, (1,706 reviews)
"The breakfast and the staff were great!"
United States
Xochitl
The price is S$146
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Chula Vista San Diego South
A neatly arranged hotel room with a large bed, a desk, a chair, and a bedside table.

8. Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.2 out of 10, Very good, (1,143 reviews)
"Nice place for a short stay"
United States
Aida
The price is S$116
includes taxes & fees
27 Oct - 28 Oct
Valli Hi Motel
View from property

9. SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (801 reviews)
"Great hotel and service"
United States
Joey
The price is S$253
includes taxes & fees
8 Nov - 9 Nov
SpringHill Suites by Marriott Chula Vista Eastlake
A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.

10. The Rambler Hotel

The Rambler Hotel
3.0 star property
14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,208 reviews)
"Friendly staff, awesome comfortable rooms,sweet shower,& delicious latte @ the fun café. Will definitely stay again."
United States
Marisa
The price is S$169
includes taxes & fees
8 Nov - 9 Nov
The Rambler Hotel
A hotel room with two beds, a desk, and a chair.

11. Howard Johnson by Wyndham National City/San Diego South

Howard Johnson by Wyndham National City/San Diego South
2.0 star property
18.3 km from Otay Mesa
7.6 out of 10, Good, (1,170 reviews)
"Very clean and friendly would stay here again"
Canada
Michelle
The price is S$114
includes taxes & fees
19 Oct - 20 Oct
Howard Johnson by Wyndham National City/San Diego South
A Holiday Inn Express building with a prominent entrance, palm trees, and a clear sky.

12. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,617 reviews)
"Was a great stay!!"
United States
Taylor
The price is S$223
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express San Diego South - Chula Vista by IHG
A modern kitchen area with a self-serve station, including a waffle maker, coffee machine, and various food items.

13. Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.1 km from Otay Mesa
8.0 out of 10, Very good, (2,016 reviews)
"Great staff help me out on any questions I'll stay here again"
United States
Eric
The price is S$155
includes taxes & fees
25 Oct - 26 Oct
Best Western Chula Vista/Otay Valley Hotel
A hotel room with a large bed, a desk, a chair, a painting, and a view of the city.

14. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,205 reviews)
"Great property and we enjoyed the stay"
United States
Suresh
The price is S$214
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Marina Gateway Hotel
A hotel room with a bed, a desk with a chair, a nightstand, and a wall-mounted TV displaying a sunset scene.

15. Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
14.4 km from Otay Mesa
7.4 out of 10, Good, (2,398 reviews)
"A modest and clean hotel, recommended, with reasonable prices."
United States
AHMAD
The price is S$95
includes taxes & fees
17 Nov - 18 Nov
Hotel Palmeras Chula Vista
A modern hotel with a prominent 'Hercor Hotel' sign, multiple balconies, and a 'Urban Boutique' label.

16. Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,559 reviews)
"Clean room, friendly staff"
United States
Avery
The price is S$146
includes taxes & fees
9 Nov - 10 Nov
Hercor Hotel - Urban Boutique
A modern outdoor seating area with wicker chairs, a round table, and a fire pit.

17. TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown
3.0 star property
25 km from Otay Mesa
8.8 out of 10, Excellent, (1,002 reviews)
"Clean and spacious rooms, great staff, great service!"
United States
Brajesh
The price is S$159
includes taxes & fees
8 Nov - 9 Nov
TownePlace Suites by Marriott San Diego Downtown
A hotel with a central courtyard, palm trees, and a fountain.

18. Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 30.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,527 reviews)
"Nice, clean hotel for a quick stay."
United States
Kristen
The price is S$165
includes taxes & fees
15 Nov - 16 Nov
Hilton Garden Inn San Diego Old Town/SeaWorld Area
A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.

19. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.4 out of 10, Very good, (1,415 reviews)
"Great place to stay"
United States
Chris
The price is S$168
includes taxes & fees
9 Nov - 10 Nov
Crowne Plaza San Diego - Mission Valley by IHG
A hotel courtyard with outdoor seating, palm trees, and a view of the ocean at dusk.

20. Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6,346 reviews)
"Wonderful staff and a great location"
United States
Jonathan
The price is S$270
includes taxes & fees
22 Oct - 23 Oct
Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A pier extending into the ocean with buildings at the end, under a partly cloudy sky.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa Hotel Reviews

Ocean Beach Hotel

Ocean Beach Hotel

10/10 Excellent
"We love getting our balcony room, we request the same same room every year. The staff is very friendly and accomdating."
Dana 3-night trip
Posted less than an hour ago
Ocean Beach Hotel

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on our traveller data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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