What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

How many hotels are there in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodation options in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

Top 10 Otay Mesa West Hotels of 2025

Top 10 Hotels in Otay Mesa West

3 outdoor pools, pool cabanas (surcharge), pool umbrellas

"I always enjoy staying here "

Desk, laptop workspace, iron/ironing board, free WiFi

"Great place!"

includes taxes & fees

24 Jun - 25 Jun

"Good place for short stay"

includes taxes & fees

22 Jun - 23 Jun

"Great place very clean and nice staff!"

includes taxes & fees

6 Jul - 7 Jul

"Clean room, beautiful and modern property, friendly staff and good breakfast!"

includes taxes & fees

30 Jun - 1 Jul

"Great property, and customer service."

includes taxes & fees

22 Jun - 23 Jun

Outdoor pool, pool umbrellas, pool loungers

"Small rooms but friendly staff and prime location"

includes taxes & fees

22 Jun - 23 Jun

"Nice place to stay "

"Good service,nice breakfast "

includes taxes & fees

29 Jun - 30 Jun

"Had a very nice stay."

includes taxes & fees

22 Jun - 23 Jun

Desk, blackout curtains, iron/ironing board, free WiFi

"Clean quiet and staff is friendly!"

includes taxes & fees

29 Jun - 30 Jun

Desk, blackout curtains, soundproofing, free WiFi

"Affordable and near the border for convenience. "

1 bedroom, pillow-top beds, in-room safe, desk

"We really enjoy this hotel, it was clean and the service was excellent."

includes taxes & fees

26 Jun - 27 Jun

"Nice hotel "

"decent place to stay "

includes taxes & fees

29 Jun - 30 Jun

"Had a really nice stay!!"

includes taxes & fees

20 Jul - 21 Jul

Daily continental breakfast (USD 13.49 per person)

"Excellent staff willing to assist and help with any questions. Most comfortable stay, I will definitely be back. "

includes taxes & fees

6 Jul - 7 Jul

"Enjoyed our stay"

includes taxes & fees

22 Jun - 23 Jun

"Very clean and good servive and good breakfast. Great location"

includes taxes & fees

26 Jun - 27 Jun

"Great location within walking distance from the places we wanted to visit."

includes taxes & fees

29 Jun - 30 Jun

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

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Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

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Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

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