San Sisto Holidays
- Plan, book, travel with confidence
- Better togetherSave up to S$1,300 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in San Sisto
Villa di Piazzano - Small Luxury Hotel of the World
"The Hotel and grounds are beautiful and immaculately maintained. The entire staff really stands out. So friendly and welcoming. Those little gestures of respect and kindness are appreciated. Also it’s very convenient that they can speak English. There are several beautiful hotels in the area to experience, ..."
Reviewed on 14 May, 2026
TH Assisi - Hotel Cenacolo
Hotel Sangallo Palace
"Staff, breakfast , size of the room with a view all excellent"
Reviewed on 22 May, 2026
Popular places to visit
National Gallery of Umbria
Discover Umbria’s cultural treasures at its most comprehensive art gallery, where centuries-old works of art bring the past to life.
Renato Curi Stadium
Catch an event at Renato Curi Stadium during your trip to Perugia. Discover the local chocolate shops and its jazz scene while you're in the area.
Monte Tezio
Commune with nature and explore the great outdoors at Monte Tezio during your travels in Perugia. Discover the local chocolate shops and its jazz scene while you're in the area.
What to do in San Sisto
Perugia: San Lorenzo Cathedral Audioguide Tour
Perugia: Old Town Walking Tour, Piazza IV Novembre
Pic nic Deluxe Assisi and wine tasting 5 wines
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.
