Sanctuary Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to S$134 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
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West End

3 out of top 10 points of interest in this area

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Find hotels in West End

Top hotels in Sanctuary

Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
The price is S$493 per night from 28 Jan to 29 Jan
S$493
28 Jan - 29 Jan
includes taxes & fees
9/10 Wonderful! (1,559 reviews)
Stayed for 5 nights and would pick this place again. Right on the beach in a quiet area. The room was spacious and spotless. Appreciated the big shower. Pool area looked nice although I didn't use it as the weather was a little cool for the pool. Very courteous staff.

Reviewed on 25 Jan, 2026

Sanibel Island Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is S$407 per night from 28 Jan to 29 Jan
S$407
28 Jan - 29 Jan
includes taxes & fees
9/10 Wonderful! (1,145 reviews)
Love this place!!

Reviewed on 22 Jan, 2026

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is S$523 per night from 28 Jan to 29 Jan
S$523
28 Jan - 29 Jan
includes taxes & fees
8.8/10 Excellent! (1,823 reviews)
Rooms were clean. Staff was friendly The place was top-notch.

Reviewed on 25 Jan, 2026

Margaritaville Beach Resort Fort Myers
See all 12,992 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanctuary holiday package cost?
Starting from as little as , you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary holiday package makes it easy to organise your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary holiday?
Reward yourself with the biggest variety at the lowest prices by booking your holiday to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're travelling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including holiday rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia holiday package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary holiday package?
Don't stress if you're rethinking your Sanctuary holiday package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.

Things to do

Ft Myers Beach Tiki Pub Fun in the Sun Dolphin Cruise

Ft Myers Beach 2 Hour Tiki Pub Fun in the Sun Dolphin Cruise

S$77
per adult
Ft Myers Beach 2 Hour Tiki Pub Fun in the Sun Dolphin Cruise
Copacetic Day Sail

Copacetic Day Sail

S$90
per adult
100% of travellers recommend
Copacetic Day Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

S$82
per adult
Dolphin Wildlife Cruise Fort Myers Beach
See all activities in Sanibel

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.