Hotels in Sanctuary

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Jan - 27 Jan
Tomorrow
27 Jan - 28 Jan
This weekend
30 Jan - 1 Feb
Next weekend
6 Feb - 8 Feb

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanctuary hotels

BBQ/picnic Area

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (225 reviews)
"Very clean very nice staff"
United States
Edward
The price is S$142
includes taxes & fees
6 Feb - 7 Feb
Matlacha on Shoreview
Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,011 reviews)
"Amazing room and view. Great place to stay/vacation. Would come back over and over again. "
United States
Frank
The price is S$376
includes taxes & fees
8 Feb - 9 Feb
The Westin Cape Coral Resort At Marina Village
Balcony view

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,005 reviews)
"Very good 👍 "
United States
Verona
The price is S$124
includes taxes & fees
28 Jan - 29 Jan
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
In-room safe, desk, laptop workspace, blackout curtains

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,190 reviews)
"Is great place to stay."
United States
Anastassia
The price is S$204
includes taxes & fees
1 Feb - 2 Feb
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lobby

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,004 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is S$197
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
Terrace/patio

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,227 reviews)
"Nice place for the price. "
United States
Adam
The price is S$243
includes taxes & fees
29 Jan - 30 Jan
Dolphin Key Resort
Terrace/patio

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (150 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is S$367
includes taxes & fees
23 Feb - 24 Feb
Off the Charts Inn & Out Island Resort
Terrace/patio

White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.2 out of 10, Very good, (50 reviews)
"Place was nice and private. "
United States
Dawn
The price is S$162
includes taxes & fees
28 Jan - 29 Jan
White Orchid Apartments
Living area

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very good, (11 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is S$173
includes taxes & fees
29 Jan - 30 Jan
Summerwind Studios
On the beach, sun-loungers, beach towels

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,563 reviews)
"Sweet staff, amazing beach access, pool, restaurant on site. Good value and great stay!"
United States
Freda
The price is S$493
includes taxes & fees
28 Jan - 29 Jan
Sanibel Island Beach Resort
Exterior

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.4 out of 10, Very good, (18 reviews)
"Great mattress, enjoyed the recliners, we prefer no doors on the closet making it fast & easy to access our wardrobe, liked the Roku TV, liked the induction stove top and drainer for washing our dishes daily as opposed to having a dishwasher. "
United States
Bobbi
The price is S$165
includes taxes & fees
28 Jan - 29 Jan
TriLuxe Inn & Studios
View from property

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1,006 reviews)
"Great location "
United States
Lance
The price is S$584
includes taxes & fees
29 Jan - 30 Jan
Marriott Sanibel Harbour Resort & Spa
Exterior

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,005 reviews)
"Great place to stay."
United States
David
The price is S$159
includes taxes & fees
30 Jan - 31 Jan
Candlewood Suites Fort Myers Sanibel Gateway by IHG
Bar (on property)

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,004 reviews)
"Great stay "
United States
Brandon
The price is S$259
includes taxes & fees
29 Jan - 30 Jan
Doubletree by Hilton Fort Myers at Bell Tower Shops
Terrace/patio

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,009 reviews)
"Great stay"
United States
Erica
The price is S$247
includes taxes & fees
29 Jan - 30 Jan
Hilton Garden Inn Ft Myers
Exterior

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location"
United States
Sandra
The price is S$583
includes taxes & fees
3 Feb - 4 Feb
Sanibel Inn
Free daily buffet breakfast

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1,002 reviews)
"Staff was great!"
United States
Jeff
The price is S$248
includes taxes & fees
28 Jan - 29 Jan
Residence Inn by Marriott Fort Myers Sanibel
Lobby lounge

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (811 reviews)
"Good location "
United States
Lynn
The price is S$183
includes taxes & fees
1 Feb - 2 Feb
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Property amenity

Island Inn

Island Inn
3.5 star property
West End, 9.6 km from Sanctuary
9.4 out of 10, Exceptional, (1,127 reviews)
"Everything was wonderful."
United States
Walter
The price is S$552
includes taxes & fees
1 Feb - 2 Feb
Island Inn
Exterior

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,006 reviews)
"Clean and tidy hotel, friendly staff and the breakfast is excellent. 4th time we have stayed here in last 15 months"
United Kingdom
Adam
The price is S$280
includes taxes & fees
31 Jan - 1 Feb
Homewood Suites by Hilton - Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.
Fort Myers showing a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

10/10 Excellent
"The suite was an amazing size, clean and the staff was so friendly. "
Laura 1-night trip
Posted 1 day ago
Pink Shell Beach Resort and Marina

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

Explore a world of travel with Expedia