Santa Ana

Antigua Guatemala


Popular places to visit

Things to do


Top hotels in Santa Ana

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is S$117 per night from 6 Jan to 7 Jan
S$117
6 Jan - 7 Jan, 2026
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (3,115 reviews)
This time we stayed a Primium level, it was a big difference in the service. Excellent service, breakfast was included which saved us money because prices are high, early check in and late check out very convenient, nice surprises every day-we loved the surprises, access to the lounge with excelent ...

Reviewed on 14 Dec, 2025

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
The price is S$169 per night from 4 Jan to 5 Jan
S$169
4 Jan - 5 Jan, 2026
includes taxes & fees
Stay at this spa hotel in Guatemala City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,004 reviews)
I’m so happy that JetBlue goes to Guatemala now nice fast and easy

Reviewed on 14 Dec, 2025

Tikal Futura Hotel & Convention Center
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is S$148 per night from 1 Jan to 2 Jan
S$148
1 Jan - 2 Jan, 2026
includes taxes & fees
Stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,618 reviews)
The room was spacious and very clean. Breakfast was great!

Reviewed on 14 Dec, 2025

Wyndham Garden Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is S$391 per night from 4 Jan to 5 Jan
S$391
4 Jan - 5 Jan, 2026
includes taxes & fees
Stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa and 2 restaurants. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,005 reviews)
as always, awesome, impressive, stunning and so relaxing!

Reviewed on 13 Dec, 2025

Hotel Museo Spa Casa Santo Domingo
Adriatika Hotel & Residence

Adriatika Hotel & Residence

4.5 out of 5
4 av 20-44 Zona 14 Guatemala City Guatemala
The price is S$149 per night from 1 Jan to 2 Jan
S$149
1 Jan - 2 Jan, 2026
includes taxes & fees
Stay at this luxury hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (940 reviews)
Beautiful property, great staff

Reviewed on 13 Dec, 2025

Adriatika Hotel & Residence
Hotel Las Americas

Hotel Las Americas

4 out of 5
Avenida Las Americas 9-08, Zona 13 Guatemala City Guatemala
Stay at this business-friendly hotel in Guatemala City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their ...
8.2/10 Very Good! (1,000 reviews)
Check in agent was excellent, profesional, attentive, the room was clean, comfortable beds, clean bathroom and bathtub, hot water excellent

Reviewed on 13 Dec, 2025

Hotel Las Americas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
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Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Historic Center


Santa Ana