Taking the local weather in Santa Cruz de Mompox into account can help you maximise your time at the pool during your trip. The hottest months are usually February and March, with an average temperature of 29°C, while the coldest months are November and October, with an average of 27°C. The rainiest months in Santa Cruz de Mompox are May, October, August and September, with each month seeing an average of 365 mm of rainfall.