Santa Cruz Tlaxcala Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to S$134 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.
Book now

Top hotels in Santa Cruz Tlaxcala

Fiesta Inn Parque Puebla

Fiesta Inn Parque Puebla

3.5 out of 5
Calzada Ignacio Zaragoza, Número 410 Puebla PUE
Fully refundableReserve now, pay when you stay
The price is S$120 per night from 1 Mar to 2 Mar
S$120
1 Mar - 2 Mar
includes taxes & fees
9.4/10 Exceptional! (818 reviews)
The hotel ia very nice, clean, practical. Rooms are comfortable. Staff is very nice.

Reviewed on 24 Dec, 2025

Fiesta Inn Parque Puebla
Ramada Encore Puebla Mexico

Ramada Encore Puebla Mexico

4 out of 5
Lateral del Anillo Periferico Coronango PUE
Fully refundableReserve now, pay when you stay
The price is S$107 per night from 15 Feb to 16 Feb
S$107
15 Feb - 16 Feb
includes taxes & fees
9.2/10 Wonderful! (1,008 reviews)
Staff was great and friendly Working on Bathrooms

Reviewed on 18 Dec, 2025

Ramada Encore Puebla Mexico
Gran Hotel de Puebla by HNF

Gran Hotel de Puebla by HNF

4 out of 5
Blvd Hermanos Serdan, 794 Puebla PUE
Fully refundableReserve now, pay when you stay
The price is S$97 per night from 20 Feb to 21 Feb
S$97
20 Feb - 21 Feb
includes taxes & fees
9.2/10 Wonderful! (518 reviews)
Bien

Reviewed on 9 Feb, 2026

Gran Hotel de Puebla by HNF
See all 222 properties in Santa Cruz Tlaxcala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.