𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Santa Fe (2026)

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Our top choices for Santa Fe hotels

A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.

A modern office space with a reception desk, several chairs, a large window, and a colorful abstract painting on the wall.

A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

A hotel room with a bed, a desk with a chair, a television, and a blue sofa.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Alachua

Tobias

S$152

includes taxes & fees

5 Oct - 6 Oct

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

A reception desk with a "Welcome to the Sun Shine State" sign, a "Treats" sign, and a minibar area with a "Hilton" sign.

2. Hampton Inn & Suites Alachua I-75

Alachua

Pamela

S$152

includes taxes & fees

4 Oct - 5 Oct

A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.

A spacious lobby with a large painting, a fireplace, a piano, and multiple seating areas.

A living room with a brown leather sofa, a glass-top coffee table, and a framed picture on the wall.

3. Best Western Gateway Grand

Gainesville

Jason

S$133

includes taxes & fees

28 Sept - 29 Sept

A fitness center with treadmills, exercise bikes, and weights.

A motel with a covered entrance, multiple parking spaces, and a fire extinguisher on the wall.

A swimming pool with a clear blue water surface, surrounded by a brick deck and a metal fence.

A modern hotel room with a large bed, a desk, a chair, a TV, and a mural of a landscape.

4. Clarion Pointe Alachua - Gainesville Area

Alachua

María Teresa

S$93

includes taxes & fees

18 Oct - 19 Oct

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.

A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.

A hotel lobby with a seating area featuring sofas and armchairs, a central coffee table, and a flat-screen TV mounted on the wall.

5. La Quinta by Wyndham Gainesville

Gainesville

Elizabeth

S$137

includes taxes & fees

28 Sept - 29 Sept

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.

A swimming pool with lounge chairs and umbrellas, a covered seating area, and a multi-story building with balconies.

A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

6. Quality Inn Alachua - Gainesville Area

Alachua

Deborah

S$109

includes taxes & fees

18 Oct - 19 Oct

A stone water feature with cascading water, surrounded by a brick wall and greenery.

A covered outdoor area with a paved walkway leading to a seating area, surrounded by greenery and a clear sky.

A spacious living area with a wooden floor, a blue sofa, a round coffee table, and a ceiling fan.

A reception desk with a modern design, a ceiling fan, and a seating area with chairs and a table.

7. BlueGem Motel

High Springs

Wesley

S$141

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, and a television.

A large, empty parking lot with marked parking spaces and a few trees in the background.

A bathroom with a white sink, mirror, and towel rack.

A parking lot with marked lanes and a grassy area on one side.

8. Royal Inn

Alachua

Alec

S$103

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.

A building with a Coca-Cola vending machine, a window with a 'OPEN' sign, and a red awning.

A bathroom with a large mirror, a sink, and a towel rack.

A reception area with a counter, a computer, and a bulletin board with pamphlets.

9. Palms Garden Inn

Lake City

Sherry

S$90

includes taxes & fees

27 Oct - 28 Oct

A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.

A row of motel buildings with a fire hydrant and trees in front.

A stone outdoor seating area with a table and benches, a trash bin, and a building in the background.

A bedroom with a bed, a chair, a dresser, a ceiling fan, a window with blinds, and a wall-mounted air conditioner.

10. High Springs Country Inn

High Springs

Luis

S$86

includes taxes & fees

4 Oct - 5 Oct

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.

A hotel room with two beds, a TV, a desk, and a chair.

A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

11. Holiday Inn Express Starke by IHG

Starke

Judy

S$156

includes taxes & fees

4 Oct - 5 Oct

A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.

A living room with a grey sofa, a wooden coffee table, and a framed horse picture on the wall.

A narrow kitchen with a wooden ceiling, a green refrigerator, and a wooden countertop.

12. Vista Verde Farm Retreat

Lake City

Stacy

S$251

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.

A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.

A living room with a curved sofa, a wooden cabinet, and a fish tank.

13. Best Western Waldo Inn and Suites

Waldo

Ana Laura

S$195

includes taxes & fees

5 Oct - 6 Oct

A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.

A hotel reception desk with a wooden panel design, a digital kiosk, and a "Welcome to the Sun Shine State" sign.

A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.

A hotel room with a living area, kitchenette, and a large mirror.

14. Hampton Inn Gainesville

Gainesville

Phillip

S$125

includes taxes & fees

4 Oct - 5 Oct

A multi-story hotel with a central entrance, palm trees, and a clear sky.

A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.

A modern living room with a green sofa, a round coffee table, and a fireplace.

A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

15. Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

sherry

S$127

includes taxes & fees

4 Oct - 5 Oct

A hotel entrance with a covered driveway, flag poles, and a well-lit facade.

A modern dining area with a wooden table, four chairs, and a fireplace.

An outdoor seating area with tables and chairs, surrounded by greenery and a building with large windows.

A grocery store interior with shelves stocked with snacks, beverages, and packaged goods.

16. Hilton Garden Inn Gainesville

Gainesville

jose

S$128

includes taxes & fees

28 Sept - 29 Sept

An outdoor patio with wicker furniture, stone walls, and a barbecue grill.

TownePlace Suites Marriott with a modern exterior, multiple windows, and a covered entrance area.

A modern dining area with a wooden table, blue upholstered chairs, and pendant lighting.

A modern hotel room with a flat-screen TV, a dining area with a table and chairs, a kitchenette, and a wardrobe with hanging space.

17. TownePlace Suites by Marriott Gainesville Northwest

Gainesville

Tanya

S$150

includes taxes & fees

29 Sept - 30 Sept

A modern hotel lobby with a curved ceiling, a central seating area with a sofa and ottoman, a bar area, and a dining space with chairs and tables.

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and large windows offering views of the outside.

A hotel reception area with a curved reception desk, a refrigerator stocked with beverages, and a wall with a blue abstract design.

A modern hotel lobby with a breakfast bar, seating area, and a large window.

18. SpringHill Suites by Marriott Gainesville

Gainesville

Robert

S$123

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.

A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.

A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.

19. Drury Inn & Suites Gainesville

Gainesville

Joan

S$151

includes taxes & fees

1 Oct - 2 Oct

A reception area with a desk, two chairs, framed pictures, and a sign for Days Inn.

20. Days Inn by Wyndham Gainesville Hospital/University Area

Gainesville

Andrew

S$87

includes taxes & fees

28 Sept - 29 Sept

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Top Santa Fe Hotel Reviews

Hilton University of Florida Conference Center Gainesville

10/10 Excellent

"Only thing I didn’t like was the breakfast vouchers that essentially cover nothing so don’t feel like you’re getting any perk all I really want you to do is go down and buy their breakfast"

Drury Inn & Suites Gainesville

10/10 Excellent

"Had a wonderful stay! The room was very clean!"

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"♥️❤️"

Red Roof Inn PLUS+ Gainesville

10/10 Excellent

"Clean and safe good bedding good staff."

Comfort Suites Gainesville near University

8/10 Good

"Good breakfast but the trash bins by the elevators weren't cleaned out regularly and therefore smelled a bit funky."

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL

S$87

1 Oct - 2 Oct

includes taxes & fees

7.4/10 Good! (1,327 reviews)

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL

S$104

29 Sept - 30 Sept

includes taxes & fees

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL

S$104

4 Oct - 5 Oct

includes taxes & fees

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL

S$116

18 Oct - 19 Oct

includes taxes & fees

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL

S$117

18 Oct - 19 Oct

includes taxes & fees

8.2/10 Very good! (1,101 reviews)

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL

S$117

18 Oct - 19 Oct

includes taxes & fees

9.2/10 Wonderful! (1,504 reviews)

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Sleep Inn & Suites University/Shands and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

What is staying in Santa Fe like?

Travellers to Santa Fe will find plenty to explore and enjoy. There are 802 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.

What is there to see in Santa Fe?

Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Devil's Milhopper Geological State Park. You'll also find Gainesville Raceway and Poe Springs Park in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.

What's the weather like in Santa Fe?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

Explore a world of travel with Expedia

Things to do in Northeast Florida

Santa Fe Hotels from S$86

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Fe

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe hotels

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

2. Hampton Inn & Suites Alachua I-75

3. Best Western Gateway Grand

4. Clarion Pointe Alachua - Gainesville Area

5. La Quinta by Wyndham Gainesville

6. Quality Inn Alachua - Gainesville Area

7. BlueGem Motel

8. Royal Inn

9. Palms Garden Inn

10. High Springs Country Inn

11. Holiday Inn Express Starke by IHG

12. Vista Verde Farm Retreat

13. Best Western Waldo Inn and Suites

14. Hampton Inn Gainesville

15. Country Inn & Suites by Radisson, Gainesville, FL

16. Hilton Garden Inn Gainesville

17. TownePlace Suites by Marriott Gainesville Northwest

18. SpringHill Suites by Marriott Gainesville

19. Drury Inn & Suites Gainesville

20. Days Inn by Wyndham Gainesville Hospital/University Area

Top Santa Fe Hotel Reviews

Hilton University of Florida Conference Center Gainesville

Drury Inn & Suites Gainesville

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Red Roof Inn PLUS+ Gainesville

Comfort Suites Gainesville near University

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Days Inn by Wyndham Gainesville University I-75

HOM Hotel Gainesville, SureStay Collection by Best Western

Sleep Inn & Suites University/Shands

Comfort Inn Gainesville - University Area

Comfort Suites Gainesville near University

Frequently asked questions

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