𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 O Brien (2026)

A calm river with clear water, surrounded by dense trees and rocky banks.

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Pool

Cottage

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Waterpark

Condo

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Our top choices for O Brien hotels

An indoor swimming pool with clear water, surrounded by glass doors and windows, and a wooden deck area.

A modern lounge area with a fireplace, comfortable seating, a dining table, and a large window offering a view.

A modern dining area with multiple tables and chairs, a kitchen in the background, and a 'Hello Fall' sign on the wall.

A modern living room with two green sofas, a white coffee table, and a flat-screen TV mounted on the wall.

1. Fairfield Inn & Suites Lake City

Lake City

Jordan

S$149

includes taxes & fees

12 Oct - 13 Oct

A hotel room with a gray sofa, a bed with white linens, a desk with a chair, and a window with blinds.

A modern hotel lobby with a central island table, seating area with chairs, a fireplace, and a bar area.

A modern hotel lobby with a fireplace, seating areas, and a bar.

2. Comfort Suites Lake City

Lake City

Carma

S$134

includes taxes & fees

18 Oct - 19 Oct

A spacious living area with a grey sofa, a coffee table, and a TV stand.

A modern kitchen with light wood cabinets, granite countertops, and stainless steel appliances. There are signs on the wall advertising different coffee brands.

A hotel entrance with a covered walkway, palm trees, and a clear sky.

A hotel room with a sofa, a small table, a lamp, and artwork on the wall.

3. Best Western Plus Lake City

Lake City

marta

S$115

includes taxes & fees

1 Nov - 2 Nov

A modern restaurant with round tables and yellow chairs, a bar area with a TV, and a menu display.

A multi-story hotel with a modern design, featuring a prominent entrance and a parking area.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

4. Courtyard By Marriott Lake City

Lake City

Angel

S$167

includes taxes & fees

12 Oct - 13 Oct

A self-service beverage station with a variety of drinks, snacks, and a refrigerated section.

A modern hotel lobby with a central counter displaying snacks and beverages, two digital screens above the counter, and a seating area with a view of the lobby.

An outdoor patio with a stone fire feature, blue cushioned seating, and a grill.

A modern interior with two red chairs and a small table, large windows, and hanging pendant lights.

5. Tru by Hilton Lake City

Lake City

Carlos

S$145

includes taxes & fees

18 Oct - 19 Oct

A hotel pool area with lounge chairs and umbrellas, a pool with metal railings, and a building with multiple floors and large windows.

A Hampton Inn & Suites hotel with a modern design, featuring a prominent red sign, a covered entrance, and a parking area.

An outdoor patio area with tables and chairs, surrounded by a metal fence, and umbrellas providing shade.

A conference room with rows of chairs, a projector screen, and a carpeted floor.

6. Hampton Inn & Suites Lake City

Lake City

James

S$151

includes taxes & fees

18 Oct - 19 Oct

A La Quinta hotel with a modern facade, multiple windows, and a well-lit entrance.

A modern restaurant with a long counter, multiple seating options including red and yellow chairs, and a large window providing a view.

A modern lobby with a large map mural, a wooden column, and a seating area with a yellow cushion.

A modern kitchen area with a coffee station, including a coffee machine, cups, and a toaster.

7. La Quinta Inn & Suite by Wyndham Lake City

Lake City

Steven

S$135

includes taxes & fees

13 Oct - 14 Oct

A picnic table with a potted plant, located in a grassy area with a tree and a road in the background.

A hotel lobby with a reception desk, a clock, a plant, a water dispenser, and a coffee station.

A hotel room with two beds, a nightstand with a phone and remote, and a patterned curtain.

A living room with a black leather sofa, a wooden coffee table with a plant, and framed pictures on the wall.

8. Americas Best Value Inn Lake City

Lake City

Sara

S$97

includes taxes & fees

11 Oct - 12 Oct

A covered outdoor area with a paved walkway, benches, and potted plants.

A grassy area with a picnic table, a car parked in front of a building with a sloped roof, and trees with hanging moss.

A bedroom with a bed, a desk, a chair, and a ceiling fan.

A compact kitchen with a blue refrigerator, a black coffee maker, a microwave, and a small black refrigerator.

9. Cindys Motel

Mayo

Diane

S$120

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio with a stone fire pit, grey cushioned seating, and wicker ottomans.

A modern hotel room with a bed, a desk with a computer, a TV, and a lamp.

A modern hotel with a two-story structure, a covered outdoor seating area, and a parking lot with marked spaces.

A modern kitchen with stainless steel appliances, a dishwasher, and a built-in oven.

10. Home2 Suites by Hilton Lake City

Lake City

William

S$164

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a teal accent wall, a sofa, a desk with a chair, a small table, and two framed artworks.

A hotel room with two beds, a TV, a desk with a lamp, and a window with blinds.

A hotel lobby with multiple seating areas, a bar, and an elevator.

A hotel room with a beige sofa, a small table with a book, a TV on a wooden cabinet, and a window with blinds.

11. Holiday Inn & Suites Lake City by IHG

Lake City

C.jeffery

S$145

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with wicker chairs, a round table, and a fire pit.

A modern interior with a sofa, round tables, and chairs, a TV mounted on the wall, and a patterned wall.

A modern interior with a central kitchen area, a seating area with a sofa and chairs, and a large window providing natural light.

A modern interior with a dark wood desk, a blue chair, a sofa, and a patterned rug.

12. TownePlace Suites by Marriott Lake City

Lake City

Jennifer

S$171

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large bed, a desk with a computer, a television, and a window with curtains.

An aerial view of a hotel with a swimming pool, parking lot, and surrounding greenery.

A restaurant with a yellow accent wall, white tiled floor, and black and blue chairs.

13. Super 8 by Wyndham Lake City

Lake City

Scott

S$88

includes taxes & fees

2 Nov - 3 Nov

A hotel room with two beds, a TV, a desk, and a painting of a sunset.

A reception area with a wooden counter, a clock, and a computer on a desk.

A kitchen with a black refrigerator and a microwave on a wooden shelf.

A hotel room with a large bed, a bedside table, a nightstand, a window, and a bathroom with a toilet and sink.

14. Days Inn by Wyndham Lake City I-75

Lake City

Wilberd

S$104

includes taxes & fees

7 Oct - 8 Oct

A spacious lobby with a high ceiling, a large window, a dining area with green chairs, and a black door leading outside.

A white building with multiple windows and a sign that reads 'Quality Inn.'

A reception area with a counter, a coffee machine, and a potted plant.

A hotel room with two beds, a desk, a chair, a painting on the wall, and a patterned carpet.

15. Quality Inn Lake City

Lake City

Brianna

S$115

includes taxes & fees

25 Oct - 26 Oct

An aerial view of a campground with RVs, a swimming pool, and tennis courts.

A wooden cabin with a porch, a front door, and a small window.

A serene lakeside campsite with picnic tables and chairs.

A wooden cabin with a kitchen, a bathroom, and a loft bedroom.

16. Suwannee River Rendezvous

Mayo

Beth

S$154

includes taxes & fees

7 Oct - 8 Oct

A reception area with a Baymont Inn & Suites sign, a reception desk, a glass-top table, and a door.

A breakfast bar with a coffee machine, a microwave, and a sign reading "Breakfast Corner." There are several wooden tables and chairs arranged around the bar.

A hotel room with a patterned carpet, a sofa, a TV, a desk, and a bed with a patterned bedspread.

A bridge over a pond with a fountain, surrounded by palm trees and a building with a red roof.

17. Baymont by Wyndham Lake City I-75

Lake City

Steve

S$83

includes taxes & fees

11 Oct - 12 Oct

A gym with exercise equipment, a mirrored wall, and a blue accent wall.

A hotel with a covered entrance, a sign indicating it is a Holiday Inn Express, and a well-maintained lawn area.

A modern restaurant with a central counter, red chairs, and a blue and white color scheme.

A reception area with a counter, seating, and a fireplace.

18. Holiday Inn Express & Suites Live Oak by IHG

Live Oak

Tammy

S$160

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a blue wall, and a window with curtains.

A modern kitchen with a built-in stove, a coffee machine, and a sink. There is a trash can and a potted plant near the sink.

A modern living room with a sofa, armchairs, a coffee table, and a reception desk.

19. Gateway Inn

Lake City

Karen

S$68

includes taxes & fees

7 Oct - 8 Oct

A building entrance with a blue door, a security warning sign, and a window overlooking a parking area.

A hotel room with a large bed, two bedside tables, and a headboard.

A two-story building with a parking lot, a white car, and a potted plant.

A building with a distinctive yellow facade and a blue sign that reads "Royal Inn."

20. Royal Inn

Live Oak

Roscoe

S$84

includes taxes & fees

7 Oct - 8 Oct

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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Tru by Hilton Lake City

8/10 Good

"A little too loud at night due to freeway traffic."

Holiday Inn Express & Suites Live Oak by IHG

10/10 Excellent

"Angela was wonderful, smooth check in. Room was clean and the bed was so comfortable. All staff was very friendly and helpful. Breakfast was good."

Hampton Inn & Suites Alachua I-75

10/10 Excellent

"Great place"

Quality Inn & Suites Live Oak I-10 Exit 283

8/10 Good

"Rooms are ok, pretty clean, problem, rooms face outside, door and ac not sealed allowing bugs to walk in. For the price point, its over priced by 50. If they clean it up, clean up property more, maybe worth the price."

Baymont by Wyndham Lake City I-75

8/10 Good

"Little worn"

More cheap stays in O Brien

Baymont by Wyndham Lake City I-75

3598 W Us Highway 90 Lake City FL

S$83

11 Oct - 12 Oct

includes taxes & fees

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL

S$115

25 Oct - 26 Oct

includes taxes & fees

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

S$115

1 Nov - 2 Nov

includes taxes & fees

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL

S$134

18 Oct - 19 Oct

includes taxes & fees

Tru by Hilton Lake City

284 NW Centurion Court Lake City FL

S$145

18 Oct - 19 Oct

includes taxes & fees

9.2/10 Wonderful! (1,005 reviews)

Holiday Inn Express & Suites Live Oak by IHG

6694 Us Highway 129 Live Oak FL

S$160

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (888 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?

La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

What are some accommodation options with pools in O Brien?

La Quinta Inn & Suite by Wyndham Lake City: Provides buffet, an indoor pool and free self parking. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Best Western Plus Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.

How is it to stay in O Brien?

Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodation options to choose from. Find out more about O Brien.

What are the top places to visit in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Lafayette Blue Springs State Park and Lake City Mall in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.

What's the seasonal weather in O Brien?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

O Brien Hotels from S$83

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in O Brien

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for O Brien hotels

1. Fairfield Inn & Suites Lake City

2. Comfort Suites Lake City

3. Best Western Plus Lake City

4. Courtyard By Marriott Lake City

5. Tru by Hilton Lake City

6. Hampton Inn & Suites Lake City

7. La Quinta Inn & Suite by Wyndham Lake City

8. Americas Best Value Inn Lake City

9. Cindys Motel

10. Home2 Suites by Hilton Lake City

11. Holiday Inn & Suites Lake City by IHG

12. TownePlace Suites by Marriott Lake City

13. Super 8 by Wyndham Lake City

14. Days Inn by Wyndham Lake City I-75

15. Quality Inn Lake City

16. Suwannee River Rendezvous

17. Baymont by Wyndham Lake City I-75

18. Holiday Inn Express & Suites Live Oak by IHG

19. Gateway Inn

20. Royal Inn

Learn more about O Brien

Top O Brien Hotel Reviews

Tru by Hilton Lake City

Holiday Inn Express & Suites Live Oak by IHG

Hampton Inn & Suites Alachua I-75

Quality Inn & Suites Live Oak I-10 Exit 283

Baymont by Wyndham Lake City I-75

More cheap stays in O Brien

Baymont by Wyndham Lake City I-75

Quality Inn Lake City

Best Western Plus Lake City

Comfort Suites Lake City

Tru by Hilton Lake City

Holiday Inn Express & Suites Live Oak by IHG

Frequently asked questions

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