Hotels in Santa Lucia

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in Santa Lucia

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (231)
"The staff were lovely, the breakfast was good. Great location to walk Ortigia."
The price is S$250
includes taxes & fees
18 Jun - 19 Jun
Caportigia Boutique Hotel

Hotel Palazzo Cavalieri

4.0 star property
9.4 out of 10, Exceptional, (22)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
The price is S$169
includes taxes & fees
25 Jun - 26 Jun
Hotel Palazzo Cavalieri

Calafatari B&B

3.0 star property
10.0 out of 10, Exceptional, (5)
"Ana, una muy buena anfitriona. Todo detalle impecable. Habitación amplia, limpia y equipada. El lugar en el punto justo. El desayuno espectacular. Dulce, salado, exquisito. Para volver. "
Calafatari B&B

Piccolo Hotel Casa Mia

3.0 star property
8.6 out of 10, Excellent, (359)
"This hotel was top notch, outstanding service and location. Best breakfast we had in all of Italy and Sicily."
Piccolo Hotel Casa Mia

Grande Albergo Alfeo

4.0 star property
8.6 out of 10, Excellent, (630)
"Good proximity to Ortigia. "
Grande Albergo Alfeo

Lakkios

3.0 star property
8.8 out of 10, Excellent, (50)
"Nice location to where dining options and sites to see are numerous "
Lakkios

B&B Nike

9.0 out of 10, Wonderful, (66)
"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "
B&B Nike

Giuggiulena Villa

3.0 star property
10.0 out of 10, Exceptional, (122)
"Sabrina and Claudia are consummate hosts and understand what constitutes a high-end experience! The accommodation was spotlessly clean, the shower powerful and the rooms spacious with every comfort needed. Staying at the Giuggiulena Villa was the perfect start to our holiday, we were made to feel at home immediately! Claudia and Sabrina prepared dinner for us for the three evenings we stayed and the food was superb! We highly recommend this B & B and won’t hesitate to stay with them again when...
The price is S$425
includes taxes & fees
12 Jun - 13 Jun
Giuggiulena Villa

Re Dionisio Luxury Suites

3.0 star property
8.8 out of 10, Excellent, (51)
"Amazing boutique hotel in Siracusa coast, walkable to Ortigia and marina to do tour of Ortigia caves. "
The price is S$557
includes taxes & fees
15 Jun - 16 Jun
Re Dionisio Luxury Suites

Gymnasium

3.0 star property
9.0 out of 10, Wonderful, (35)
"Good location."
Gymnasium

Nostos rooms & Apartments

3.0 star property
9.0 out of 10, Wonderful, (256)
"Very welcoming staff "
The price is S$132
includes taxes & fees
22 Jun - 23 Jun
Nostos rooms & Apartments

Fortaleza Charme House

10.0 out of 10, Exceptional, (13)
"Very helpful host who shared lots of recommendations and tips. Great location and very nice rooms."
The price is S$229
includes taxes & fees
9 Jul - 10 Jul
Fortaleza Charme House

Fortuna Guest House

1.0 star property
9.6 out of 10, Exceptional, (12)
"The owner was really nice and helpful! Really enjoyed our stay here."
Fortuna Guest House

Isonzo Suites

8.8 out of 10, Excellent, (3)
"."
The price is S$235
includes taxes & fees
11 Jul - 12 Jul
Isonzo Suites

Residence Agatocle

9.4 out of 10, Exceptional, (6)
"We booked one of a room they have , but the air conditioner didn't work. Hopefully, another room was free, they moved us in, but the same problem. Also, the second room looked a bit outdated. Finely, they gave us the penthouse room on the top, it was really nice, and I would say, the only room worth staying there."
Residence Agatocle

B&B Siracusa

9.0 out of 10, Wonderful, (58)
"Good location, very modern clean accommodation."
The price is S$91
includes taxes & fees
13 Jun - 14 Jun
B&B Siracusa

B&B Triskeles

3.0 star property
8.0 out of 10, Very good, (52)
"Quick check in. Bright room"
The price is S$99
includes taxes & fees
7 Jul - 8 Jul
B&B Triskeles

Hotel Mediterraneo

3.0 star property
7.8 out of 10, Good, (121)
"Nice clean room, pleasant staff, great location."
The price is S$146
includes taxes & fees
12 Jun - 13 Jun
Hotel Mediterraneo

Regina Margherita

7.8 out of 10, Good, (13)
"Zentral gelegenes Hotel"
Regina Margherita

Populus

1.0 star property
7.8 out of 10, Good, (73)
"Just stay somewhere else, plain and simple."
The price is S$118
includes taxes & fees
1 Jul - 2 Jul
Populus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
Ortigia map

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Grottasanta map

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina map

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Tiche map

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Epipoli map

Epipoli

While Epipoli isn't home to many top sights, Greek Theatre of Syracuse and Archaeological Park of Neapolis are some notable places to visit nearby.

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This property offers a restaurant and free parking. Other top choices in the neighbourhood include Nostos rooms & Apartments and La casa di Aneupe.

How many hotels will I find in Santa Lucia?

Expedia has 264 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.