Photo by William Keller

Hotels in Santa Lucia

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Nov - 13 Nov
Tomorrow
13 Nov - 14 Nov
This weekend
14 Nov - 16 Nov
Next weekend
21 Nov - 23 Nov

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Santa Lucia

Soundproofing, free WiFi
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (36)
"Convenient to access as it’s located near to the train station and bus terminal. Room is large and clean. One thing I’m not satisfied is a coffee machine at breakfast room which taste wasn’t good."
Japan
Noriaki
The price is S$206
includes taxes & fees
19 Nov - 20 Nov
Hotel Palazzo Cavalieri
Aerial view
Grande Albergo Alfeo

Grande Albergo Alfeo

4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (648)
"Great location very walkable. Staff was pleasant and breakfast was plentiful and tasty. Stay here again."
United States
susan
Grande Albergo Alfeo
Terrace/patio
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (252)
"The staff were lovely, the breakfast was good. Great location to walk Ortigia."
Canada
Gregory
The price is S$212
includes taxes & fees
9 Dec - 10 Dec
Caportigia Boutique Hotel
Terrace/patio
Casa Miranda Boutique

Casa Miranda Boutique

Santa Lucia
The price is S$291
includes taxes & fees
15 Nov - 16 Nov
Casa Miranda Boutique
Memory-foam beds, in-room safe, individually furnished, desk
Fortaleza Charme House

Fortaleza Charme House

Santa Lucia
10.0 out of 10, Exceptional, (27)
"This hotel was absolutely amazing. The location was perfectly walkable to Ortigia while still having access to ample parking options. The rooms were big, impeccably clean, and comfortable. Most importantly, Francesco was soo friendly and helpful. He went above and beyond to make our stay as good as it could possibly be. He had great recommendations not only for Syracuse, but for all of Sicily. We would go back just to stay here!!! "
United States
Lauren
The price is S$220
includes taxes & fees
15 Nov - 16 Nov
Fortaleza Charme House
Premium bedding, minibar, desk, soundproofing
B&B Nike

B&B Nike

Santa Lucia
9.0 out of 10, Wonderful, (74)
"Just do it .... Perfect"
United States
Danny
B&B Nike
Coffee/tea maker, electric kettle
Nostos rooms & Apartments

Nostos rooms & Apartments

3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (272)
"Staff and clean room."
United States
John
The price is S$89
includes taxes & fees
13 Nov - 14 Nov
Nostos rooms & Apartments
Exterior
San Nicola Rooms Siracusa

San Nicola Rooms Siracusa

Santa Lucia
9.4 out of 10, Exceptional, (3)
"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"
Italy
Davide Angelo
The price is S$126
includes taxes & fees
13 Dec - 14 Dec
San Nicola Rooms Siracusa
Exterior
Hotel Le Muse

Hotel Le Muse

3.0 star property
Santa Lucia
7.4 out of 10, Good, (71)
"Extremely austere. Not having wifi in the room nowadays is like not having running water. "
United States
Jacques
The price is S$149
includes taxes & fees
22 Nov - 23 Nov
Hotel Le Muse
1 bedroom, minibar, in-room safe, desk
Lakkios

Lakkios

3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (62)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
Lakkios
Exterior
Hotel dei Coloniali

Hotel dei Coloniali

3.0 star property
Santa Lucia
7.4 out of 10, Good, (166)
"Chambre au rdc sans fenêtre ouvrante, avec mauvaise odeurs Personnel du petit déjeuner désagréable et pas compétence Environnement zone industrielle avec marchand de poisson d’où odeurs "
France
guillaume
The price is S$94
includes taxes & fees
28 Nov - 29 Nov
Hotel dei Coloniali
Terrace/patio
Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia

3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (373)
"the area felt safe with east access to Ortagia and the Duomo Angela., at reception was wonderful, breakfast was very nice, good staff"
United States
Pat
Piccolo Hotel Casa Mia
Desk, laptop workspace, free WiFi
Agorà

Agorà

Santa Lucia
10.0 out of 10, Exceptional, (1)
"Carlo was great. He wanted to help in any way. The room was excellent except for Friday night music and traffic. You want to party it is near there. Would stay there again. Walkable to most places. Good restaurants near by."
United States
Bryce
The price is S$119
includes taxes & fees
13 Nov - 14 Nov
Agorà
Water view
Re Dionisio Luxury Suites

Re Dionisio Luxury Suites

3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (56)
"Street parking was surprisingly easy. Breakfast w was excellent. "
United States
Diane
Re Dionisio Luxury Suites
Full-sized fridge, oven, stovetop, cookware/dishes/utensils
Gymnasium

Gymnasium

3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40)
"Nice kitchen area, centrally located."
United States
Richard
Gymnasium
View from room
Hotel Mediterraneo

Hotel Mediterraneo

3.0 star property
Santa Lucia
7.8 out of 10, Good, (122)
"The location of property was good. The surrounds of the property is poor. Dirty grounds. No internet, no lift. Lots of stairs. Lobby staff were ok. Breakfast waitress didn’t smile. "
Australia
LEONIE
Hotel Mediterraneo
Terrace/patio
Populus

Populus

1.0 star property
Santa Lucia
7.8 out of 10, Good, (74)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is S$121
includes taxes & fees
13 Nov - 14 Nov
Populus
View from room
Calafatari B&B

Calafatari B&B

3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B
Exterior
AmaCasa Siracusa

AmaCasa Siracusa

Santa Lucia
10.0 out of 10, Exceptional, (1)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is S$129
includes taxes & fees
13 Nov - 14 Nov
AmaCasa Siracusa
Premium bedding, desk, cots/infant beds, rollaway beds
B&B Siracusa

B&B Siracusa

Santa Lucia
9.0 out of 10, Wonderful, (59)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is S$107
includes taxes & fees
13 Nov - 14 Nov
B&B Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Neapolis

While visiting Neapolis, you might make a stop by sights like Ear of Dionysius and Roman Amphitheatre of Syracuse.

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Can't say enough great things about Algila! The staff was so helpful & accommodating, awesome location, nice rooms and large common areas to gather aft"
Kimberly 7-night trip
Posted 5 days ago
Algila' Ortigia Charme Hotel

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on Expedia customer reviews, Fortaleza Charme House is the highest ranked property in Santa Lucia. This inn is a short 6-minute walk from Lungomare di Ortigia, and it offers a beach bar and free WiFi. Other top choices in the neighbourhood include Giuggiulena Villa and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 278 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.