Top 10 Santa Lucia Hotels of 2026

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Compare popular hotels in Santa Lucia

Property	Property class	Guest rating
Nostos rooms & Apartments	3.0 star property	9.0 Wonderful 278 reviews	View
Lakkios	3.0 star property	9.0 Wonderful 65 reviews	View
Hotel Palazzo Cavalieri	4.0 star property	8.8 Excellent 41 reviews	View
Gymnasium	3.0 star property	8.8 Excellent 40 reviews	View
Re Dionisio Luxury Suites	3.0 star property	8.8 Excellent 57 reviews	View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

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Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

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Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

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Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

8/10 Good

"Great location with very accommodating and friendly staff. Large variety for buffet breakfast with ability to order from the menu. My friend and I stayed for 4 nights. We used their valet parking and the car was always delivered promptly. I didn’t choose the highest level of room available, but the rooms were fine and had a safe for valuables. Great shower. "

Grand Hotel Villa Politi

10/10 Excellent

"We loved this place. A real step back in time to a grand old hotel with lovely spacious rooms and a great menu. Staff were lovely and helpful. Our room was more than big enough for three people with a separate room for the third person so could easily have just gone for one room rather than two. "

Lanterne Magiche Ortigia

8/10 Good

"The hotel is located in a car-free zone, which made it difficult to find. The parking options are not very good. We had to park in a lot a long distance away and had concerns about the car being left. Otherwise, our stay was wonderful. Comfortable, large suite with views of the sea. Once we got settled, it was an outstanding experience to be in this area."

Ortea Palace Hotel, Sicily, Autograph Collection

6/10 Okay

"The in-room WiFi wasn’t working and they said it wouldn’t be working. That the in-room was a third party and they had no control!! Out coffee table was about to fall apart. Maintenance did come to try and save it but they couldn’t. So we had to live with it for the duration of our stay. The bar was never staffed and we had to go search for someone to assist. This is not a 5 star or 4 star hotel. It is in desperate need of help"

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Nostos rooms & Apartments.

How many hotels will I find in Santa Lucia?

Expedia has 307 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Hotels in Santa Lucia

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Our top choices for Santa Lucia hotels

Melody rooms

Calafatari B&B

Isonzo Suites

Nostos rooms & Apartments

AmaCasa Siracusa

B&B Nike

Caportigia Boutique Hotel

B&B Siracusa

San Nicola Rooms Siracusa

Fortaleza Charme House

Eos Serenity Suites

B&B L'INFIORESCENZA

Piccolo Hotel Casa Mia

Eos Sea View Apartment

Gymnasium

Lakkios

Le Camere Luxsury Rooms

Hotel Mediterraneo

Hotel Palazzo Cavalieri

Eos Elegant Apartment & Suites

Compare popular hotels in Santa Lucia

Where to stay in Santa Lucia

Ortigia

Neapolis

Grottasanta

Acradina

Tiche

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Frequently asked questions

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