Top 10 Santa Lucia Hotels of 2025

Top 10 Hotels in Santa Lucia

"Good proximity to Ortigia. "

"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."

includes taxes & fees

26 Aug - 27 Aug

"Perfect place"

includes taxes & fees

24 Aug - 25 Aug

"Wonderful property, excellent staff and the most amazing view from the apartment"

includes taxes & fees

23 Aug - 24 Aug

"Nice location to where dining options and sites to see are numerous "

1 bedroom, premium bedding, minibar, desk

"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "

"Fantastic hotel with great facilities and very friendly and helpful staff. Breakfast was very tasty (and lovely to eat on the terrace overlooking the sea). Beautiful big room with a balcony right above the sea. A lovely calm atmosphere about the whole place. It was great to be able to go downstairs for a swim with islands to sit on just at the back of the hotel. The upper floor where the loungers were was perfect and a very relaxing place to sit after exploring busy Ortigia. Sabrina also let us...

includes taxes & fees

31 Aug - 1 Sept

1 bedroom, memory-foam beds, in-room safe, individually furnished

"Very helpful host who shared lots of recommendations and tips. Great location and very nice rooms."

includes taxes & fees

21 Aug - 22 Aug

"Excellent stay, close to everything and easy parking"

includes taxes & fees

24 Aug - 25 Aug

Full-sized fridge, oven, stovetop, cookware/dishes/utensils

"Great location, clean new comfortable room and kitt. "

"Very welcoming staff "

includes taxes & fees

13 Sept - 14 Sept

"The room was great and the staff was exceptionally helpful"

"Nice clean room, pleasant staff, great location."

"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."

includes taxes & fees

24 Aug - 25 Aug

Premium bedding, desk, cots/infant beds, rollaway beds

"Good location, very modern clean accommodation."

includes taxes & fees

24 Aug - 25 Aug

1 bedroom, Egyptian cotton sheets, premium bedding, down duvets

"It was easy to register, clean and a good location. Not to mention the free croissant in the morning!"

includes taxes & fees

20 Aug - 21 Aug

"Wonderful property, well located, and memorable caring service. Anna was an outstanding host, cares and serves us every day with local fresh pastries, fruits, salumeria, assorted juices and marmalades. Grazing table all day. Room was wonderful. Lots of free and safe parking in the area. I highly recommend it."

"The location was great to explore Syracuse. Lots of surrounding restaurants to choose from too. The bed was a bit average and the television didn't work on the last night."

"The host, Raymond is very friendly. He came to meet us at the Square and explained in details on every houseware."

includes taxes & fees

27 Aug - 28 Aug

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Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

1 out of top 10 points of interest in this area

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

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Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

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Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

10/10 Excellent

"The staff was attentive and very helpful. The room amenities were very nice, especially the beautiful bathroom!"

Caportigia Boutique Hotel

10/10 Excellent

"The hotel was truly lovely, clean and in a perfect location for all our jaunts; we were greeted warmly by all staff we encountered. The included Buffet Breakfast was varied and fresh. We did not try the in-house restaurant but the menu was very interesting snd upscale. I highly recommend the Caportigia Boutique Hotel and we would gladly stay again!"

Palazzo Artemide - VRetreats

10/10 Excellent

"Fantastic location and modern hotel The negatives was parking it was extremely stressful to get the vehicle to the hotel The other issue I had there was a tip included in the final invoice this should not be done. Should you wish to tip it should be seperate and an amount of your choosing"

Re Dionisio Luxury Suites

10/10 Excellent

"My family travels a lot and this was one of our favorite hotels. The views from the spacious and modern rooms and unbelievable. We rented the hotel spa pool room for our family and it was very reasonable and definitely worth doing. It was an easy walk to Ortigia and we also walked to the Archeological Park. Breakfast was delicious and staff was very helpful. I highly recommend this hotel if you are staying in Siracusa."

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Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on Expedia customer reviews, Giuggiulena Villa is the highest ranked property in Santa Lucia. This affittacamere offers a bar and a rooftop terrace. Other top choices in the neighbourhood include Caportigia Boutique Hotel and La casa di Aneupe.

How many hotels will I find in Santa Lucia?

Expedia has 269 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Top 10 Hotels in Santa Lucia

Grande Albergo Alfeo

Grande Albergo Alfeo

Hotel Palazzo Cavalieri