Santo Domingo Holidays

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    Save up to S$1,300 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo
An aerial view of a city with a central circular plaza, surrounded by buildings and trees.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

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A large stone church with a central dome and arched entrance.

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

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A yellow building with a sign reading "El Jolgorio."

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

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A historic church with intricate architecture and a bell tower.

Historic Center

2 out of top 10 points of interest in this area

Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

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A city street at dusk with illuminated buildings, palm trees, and vehicles with light trails.

Reforma

1 out of top 10 points of interest in this area

Consider a visit to Angel of Independence Monument and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Find hotels in Reforma

Top hotels in Santo Domingo

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

Mexico City
Fully refundable
S$193
4 Oct - 5 Oct
includes taxes & fees
Camino Real Aeropuerto Mexico
Fiesta Americana Reforma

Fiesta Americana Reforma

Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
S$164
19 Sept - 20 Sept
includes taxes & fees
9.2/10 Wonderful! (5,130 reviews)
"N/a"

Reviewed on 11 Sept, 2026

Fiesta Americana Reforma
Hotel Zócalo Central

Hotel Zócalo Central

Cinco de Mayo 61 Mexico City
Fully refundableReserve now, pay when you stay
S$261
17 Sept - 18 Sept
includes taxes & fees
9.8/10 Exceptional! (2,835 reviews)
"The location is perfect, the amenities, breakfast is incredible, the downstairs snack and coffee bar were amazing. Building and decor were beautiful."

Reviewed on 12 Sept, 2026

Hotel Zócalo Central
See all 5,552 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Domingo holiday package cost?
We make it simple to see the world, with Santo Domingo packages starting from as low as . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add some activities and tours to your travel itinerary?
How do I get a cheap travel package to Santo Domingo?
Book everything all in one place with our Santo Domingo holiday packages. You'll discover deals on hotels, flights and more that'll keep your wallet happy and your spirit of adventure alive. And, with more than 550 partner airlines and 1,000,000 properties globally to choose from, there are endless opportunities to mix and match as you want.
Where should I stay in Santo Domingo?
Urban explorers come from every corner of the globe to see Basilica of Our Lady of Guadalupe and Zócalo in Santo Domingo. Book a hotel close to these top attractions and visit them at your leisure.
How far in advance should I book my Santo Domingo holiday?
It depends on the airline, but you can generally browse through international flights on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky travellers will sometimes find a cheaper ticket only weeks before the date of departure.
What does an Expedia Santo Domingo travel package include?
With Expedia, you can select a combination of hotels, car rentals and flights to build your ideal Santo Domingo package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the more discounts you'll get!
What should I know before booking a Santo Domingo travel package?
When you book your hotels, flights and car rentals together, you'll enjoy amazing discounts. Whether you're planning a beach escape in a villa or want to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Santo Domingo Expedia holiday package?
Expedia has access to more than 550 airline partners globally, so you sure can! Just choose the carrier you want and craft your ideal Santo Domingo getaway.
If I'm not able to travel, can I cancel my Santo Domingo holiday package?
Don't stress if you're rethinking your Santo Domingo holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Things to do

Turibus Hop-on Hop-off City Tour Mexico City

Hop-on Hop-off Mexico City Tour

S$24
per adult
80% of travellers recommend
Hop-on Hop-off Mexico City Tour
Teotihuacan, Shrine of Guadalupe & Tlatelolco

Teotihuacan, Shrine of Guadalupe & Tlatelolco

S$71
per adult
90% of travellers recommend
Teotihuacan, Shrine of Guadalupe & Tlatelolco
Turibus Night City Tour

Night Tour of Mexico City in a Double-Decker Bus

S$13
per adult
82% of travellers recommend
Night Tour of Mexico City in a Double-Decker Bus
See all activities in Mexico City

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.