Hotels in South Mission Beach

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Mission Beach hotels

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 9.5 km from South Mission Beach
9.0 out of 10, Wonderful, (134)
"Great place to stay "
United States
Jacorey
The price is S$186
includes taxes & fees
4 Jan - 5 Jan, 2026
Courtyard by Marriott San Diego Downtown Little Italy

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.1 km from South Mission Beach
8.4 out of 10, Very good, (6020)
"Always an amazing stay"
United States
Jana
The price is S$239
includes taxes & fees
28 Dec - 29 Dec
Wyndham San Diego Bayside

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 1.5 km from South Mission Beach
9.0 out of 10, Wonderful, (3938)
"Always love staying here. Staff was very courteous and the rooms very clean. "
United States
Eric
The price is S$231
includes taxes & fees
4 Jan - 5 Jan, 2026
The Dana on Mission Bay

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
6.7 km from South Mission Beach
8.8 out of 10, Excellent, (1309)
"Checking in was easy and friendly staff."
United States
Elvira
The price is S$130
includes taxes & fees
20 Jan - 21 Jan, 2026
Hampton Inn San Diego/Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
8.8 km from South Mission Beach
8.4 out of 10, Very good, (1422)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is S$166
includes taxes & fees
3 Jan - 4 Jan, 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 10 km from South Mission Beach
9.0 out of 10, Wonderful, (2869)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is S$332
includes taxes & fees
25 Dec - 26 Dec
Manchester Grand Hyatt San Diego

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 10.9 km from South Mission Beach
9.2 out of 10, Wonderful, (2054)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is S$348
includes taxes & fees
25 Dec - 26 Dec
Omni San Diego Hotel at the Ballpark

Handlery Hotel

Handlery Hotel
3.5 star property
7.6 km from South Mission Beach
8.2 out of 10, Very good, (2246)
"Room and staff were excellent"
United States
Bryant
The price is S$127
includes taxes & fees
20 Jan - 21 Jan, 2026
Handlery Hotel

Hampton Inn Cardiff Beach Encinitas, CA

Hampton Inn Cardiff Beach Encinitas, CA
3.0 star property
29.3 km from South Mission Beach
9.2 out of 10, Wonderful, (1043)
"Clean room and staff were excellent."
United States
Jose
The price is S$173
includes taxes & fees
1 Jan - 2 Jan, 2026
Hampton Inn Cardiff Beach Encinitas, CA

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from South Mission Beach
9.0 out of 10, Wonderful, (3159)
"Beautiful hotel"
United States
Jordan M.
The price is S$284
includes taxes & fees
1 Jan - 2 Jan, 2026
Hard Rock Hotel San Diego

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
8 km from South Mission Beach
8.0 out of 10, Very good, (2434)
"Clean room and excellent service "
United States
Jaime
The price is S$124
includes taxes & fees
4 Jan - 5 Jan, 2026
Days Inn by Wyndham San Diego Hotel Circle

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
7.3 km from South Mission Beach
8.8 out of 10, Excellent, (3571)
"Clean and the amenities were outstanding, the staff was polite and helpful 👍 "
United States
walter
Kings Inn San Diego

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
6.6 km from South Mission Beach
8.8 out of 10, Excellent, (1320)
"Great stay!"
United States
Foumi
The price is S$180
includes taxes & fees
4 Jan - 5 Jan, 2026
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
6.6 km from South Mission Beach
9.2 out of 10, Wonderful, (1044)
"Excellent staff,breakfast,transportation "
United States
Weldon
The price is S$201
includes taxes & fees
26 Dec - 27 Dec
Holiday Inn Express San Diego Airport - Old Town by IHG

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 19.1 km from South Mission Beach
8.4 out of 10, Very good, (1911)
"Excellent location"
United States
Paolo
The price is S$143
includes taxes & fees
4 Jan - 5 Jan, 2026
DoubleTree by Hilton San Diego - Del Mar

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
6.1 km from South Mission Beach
9.2 out of 10, Wonderful, (3209)
"Great stay and location!"
United States
Jason
The price is S$171
includes taxes & fees
4 Jan - 5 Jan, 2026
Bay Club Hotel & Marina

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
22 km from South Mission Beach
8.6 out of 10, Excellent, (1495)
"Everything was great, staff , Room , clean , great place to stay "
United States
Luis
The price is S$132
includes taxes & fees
4 Jan - 5 Jan, 2026
La Quinta Inn by Wyndham San Diego Chula Vista

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6.7 km from South Mission Beach
8.4 out of 10, Very good, (3169)
"Great stay! "
United States
Melissa
The price is S$231
includes taxes & fees
25 Dec - 26 Dec
Sheraton San Diego Resort

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego, 5.7 km from South Mission Beach
8.4 out of 10, Very good, (1866)
"Excellent location, courteous staff, great airport shuttle, delicious on-site restaurant."
United States
Kathleen
The price is S$171
includes taxes & fees
4 Jan - 5 Jan, 2026
Best Western Plus Hacienda Hotel Old Town

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 1.8 km from South Mission Beach
8.6 out of 10, Excellent, (2358)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is S$259
includes taxes & fees
11 Jan - 12 Jan, 2026
Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Mission Beach

Find the best South Mission Beach areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top South Mission Beach Hotel Reviews

Frequently asked questions

What's it like in South Mission Beach?
Guests are sure to enjoy their time checking out all that San Diego's South Mission Beach neighbourhood has to offer. Looking for sights you might find in a travel guide about South Mission Beach? Consider a visit to Mission Bay while you're in the neighbourhood.
How many hotels are there in South Mission Beach?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 321 South Mission Beach hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Mission Beach, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best options available in South Mission Beach.
What is there to do in this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission Beach, Mission and Pacific Beaches and South Mission Beach while you're in South Mission Beach. You could also plan a visit to Mission Bay or Belmont Park while you're in the neighbourhood. Golf Gardens Miniature Golf, Dog Beach and Bahia Point Beach are just a few of the places to visit in and around South Mission Beach. While you're out sightseeing in San Diego, make sure that you visit other sights such as Ocean Beach Athletic Area or Ocean Beach.

Explore a world of travel with Expedia