⭐ Top 10 Hotels Near South Texas Medical Center for 2026

A modern medical building with reflective glass windows and a clear sky.

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Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

A modern lobby with a grey sofa, blue armchairs, and a stone accent wall.

A hotel room with two beds, a TV, a desk with a lamp, and a dresser.

A spacious indoor area with a long wooden reception desk, multiple seating arrangements, and large windows providing natural light.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 2.9 km from South Texas Medical Center

Melissa

S$135

includes taxes & fees

9 Sept - 10 Sept

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

A reception area with a wooden reception desk, a 'Corner Market' sign, and a refrigerator stocked with beverages.

A swimming pool with a wooden ceiling, lounge chairs, and a view of trees and a building.

A Fairfield by Marriott Inn & Suites building with a modern design, featuring a prominent entrance with a covered walkway and a parking lot in front.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District, 1 km from South Texas Medical Center

Matthew

S$129

includes taxes & fees

6 Sept - 7 Sept

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

A modern hotel lobby with a mix of seating arrangements, including round tables and sofas, and a bar area with a high counter.

A courtyard with outdoor seating, a fire pit, and a covered area.

A hotel entrance with a covered walkway, a wet driveway, and a tree in the foreground.

3. Courtyard by Marriott Medical Center San Antonio

Medical Center District, 1.3 km from South Texas Medical Center

Daniel

S$147

includes taxes & fees

9 Sept - 10 Sept

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

A gym with multiple cardio machines, including treadmills and elliptical trainers, arranged in a spacious room with a carpeted floor and neutral-colored walls.

A hotel room with a large bed, a desk with a television, a chair, and a nightstand with a lamp.

A hotel with a red-roofed entrance, multiple floors, and a visible flag.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 2.4 km from South Texas Medical Center

Melissa

S$133

includes taxes & fees

9 Sept - 10 Sept

A hotel pool area with lounge chairs and a building with large windows in the background.

A large conference room with a high ceiling, large windows, and a patterned carpet.

A hotel lobby with a seating area, a large potted plant, a decorative wall, and a vintage car display.

5. The Westin San Antonio North

3.2 km from South Texas Medical Center

Noemi

S$143

includes taxes & fees

10 Sept - 11 Sept

A modern kitchen with a large window, wooden counter, and two bar stools.

A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.

A hotel room with two beds, a bedside table with a phone, a window with curtains, and a wooden floor.

6. Park Inn by Radisson, Medical Center

Medical Center District, 1 km from South Texas Medical Center

Amanda

S$94

includes taxes & fees

10 Sept - 11 Sept

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

A laundry facility with multiple washing machines, a drying rack, and instructional posters on the wall.

A compact kitchen with a built-in refrigerator, microwave, and coffee maker.

A stone facade with a 'welcome' sign, a blue door, and a parking sign.

7. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District, 2.7 km from South Texas Medical Center

Ruben

S$70

includes taxes & fees

1 Oct - 2 Oct

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

A room with a table and chairs, a clock, and framed pictures on the wall.

A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.

A hotel with a prominent 'OYO INN & SUITES' sign, featuring a two-story structure with balconies and a covered entrance.

8. OYO Inn & Suites Medical Center San Antonio

Medical Center District, 3.1 km from South Texas Medical Center

Ronnie

S$82

includes taxes & fees

30 Sept - 1 Oct

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

A hotel room with a sofa, a desk, a chair, a bed, and a mirror.

A hotel entrance with an Atria Inn & Suites sign, a Classic Collins store, and a clear sky.

A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.

9. Atria Inn & Suites

Medical Center District, 2.2 km from South Texas Medical Center

José

S$90

includes taxes & fees

2 Oct - 3 Oct

A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.

A hotel room with a bed, bedside table, desk, chair, TV, and a wardrobe.

A spacious lobby with a large refrigerator, a vending machine, and a seating area.

A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.

10. Motel 6 San Antonio, TX - Fiesta Trails

2.9 km from South Texas Medical Center

Alexis

S$67

includes taxes & fees

2 Sept - 3 Sept

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

A building with a red roof and a sign reading "Flex Studios."

A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

A hotel room with two beds, a wooden desk, and a chair.

11. Flex Studios

Medical Center District, 2.7 km from South Texas Medical Center

Jasper

S$60

includes taxes & fees

13 Sept - 14 Sept

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

A building with a stone facade, a prominent '6' sign, and a parking lot with marked handicapped spaces.

12. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District, 2.8 km from South Texas Medical Center

Rachel

S$74

includes taxes & fees

2 Oct - 3 Oct

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

An outdoor patio area with multiple tables and chairs, covered by a pergola structure.

A spacious living area with a sofa, ottoman, and a large potted plant.

13. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9 km from South Texas Medical Center

Samantha

S$141

includes taxes & fees

13 Sept - 14 Sept

A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.

A bar area with a granite countertop, multiple bar stools, and hanging pendant lights.

A large, modern hotel with multiple floors and a prominent sign reading "Embassy Suites".

A modern office space with two desks, chairs, and a large window.

14. Embassy Suites by Hilton San Antonio Landmark

La Cantera District, 8.7 km from South Texas Medical Center

Sylvia

S$246

includes taxes & fees

20 Sept - 21 Sept

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

A hotel entrance with a covered walkway, brick facade, and a sign indicating it is a Heritage Inn & Suites.

A modern hotel lobby with a reception desk, a coffee station, and a seating area.

A reception desk with a computer, framed pictures on the wall, and pendant lighting.

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown, 9.5 km from South Texas Medical Center

Victor M.

S$120

includes taxes & fees

9 Sept - 10 Sept

An outdoor patio with a stone fireplace, wicker furniture, and a view of apartment buildings.

A modern bar area with a wooden ceiling, bar stools, and a television.

A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.

A modern hotel lobby with a fireplace, comfortable seating, and a flat-screen TV.

16. Doubletree By Hilton San Antonio Northwest

La Cantera District, 9.7 km from South Texas Medical Center

Vicente

A modern hotel with a prominent sign reading "LA QUINTA".

A modern kitchen with a large window, a counter with various appliances, and a view of the parking lot.

A reception area with wooden reception desks, a cityscape mural, and a modern chandelier.

A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

9.1 km from South Texas Medical Center

Ruben

S$147

includes taxes & fees

27 Sept - 28 Sept

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

A spacious bar area with a long counter, multiple stools, and a television screen.

A lobby with a fountain, seating area, and a reception desk.

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

8.7 km from South Texas Medical Center

Kaybby

S$208

includes taxes & fees

11 Sept - 12 Sept

An outdoor patio with metal chairs, a barbecue grill, and string lights.

A modern hotel with a covered entrance, multiple floors, and a well-lit facade.

A hotel room with a bed, a sofa, a desk, a TV, and a painting on the wall.

A modern hotel lobby with a green sofa, wooden table, and chairs. There are potted plants and a sign that reads "HOME2".

19. Home2 Suites by Hilton San Antonio Airport, TX

Shearer Hills - Ridgeview, 9.4 km from South Texas Medical Center

Glen

S$147

includes taxes & fees

7 Sept - 8 Sept

A modern bar area with seating and a staircase leading to an upper level.

A lobby with a central seating area, a patterned floor, and a view of the building's interior.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

A modern building with "EMBASSY SUITES" signage, featuring a prominent entrance and landscaped surroundings.

20. Embassy Suites by Hilton San Antonio Airport

Uptown, 9.6 km from South Texas Medical Center

Alexandro

S$185

includes taxes & fees

20 Sept - 21 Sept

View all properties

Compare popular hotels close to South Texas Medical Center

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	9.2 Wonderful 1,436 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	9.0 Wonderful 1,062 reviews	View
Courtyard by Marriott Medical Center San Antonio	8.8 Excellent 1,006 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	8.4 Very good 3,613 reviews	View
The Westin San Antonio North	8.4 Very good 1,593 reviews	View

Top South Texas Medical Center Hotel Reviews

Fairfield Inn & Suites by Marriott San Antonio Medical Center

10/10 Excellent

"💯"

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

10/10 Excellent

"Staff very helpful"

Homewood Suites by Hilton San Antonio Northwest

10/10 Excellent

"Jessica was simply amazing. She was helpful, kind and accommodating. Every employee that worked there went above and beyond if I ever asked for anything. My daughter was getting married and I dressed her at the hotel, it was amazing. I can’t thank the team there enough for their kindness. The water pressure is amazing, but the tub and the rugs need a big upgrade. All in all, I loved it and will go again. I just hope the renovation gets completed soon. I will continue to use this hotel so I may visit my family. Thank you to the Homewood team! Jessica- you’re a beautiful gem :)"

Drury Inn & Suites San Antonio Northwest Medical Center

10/10 Excellent

"Very clean, staff was always kind and helpful from the front desk to the ones preparing food and any maintenance workers we encountered. The evening food and drink was a nice amenity which most places don’t offer. We always stay here when we come to San Antonio."

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

10/10 Excellent

"Very clean"

Hyatt Place San Antonio-Northwest/Medical Center

10/10 Excellent

"The staff was very friendly and helpful. Great location and the room was clean and well prepared."

Studio 6 San Antonio, Tx - Northwest Medical Center

10/10 Excellent

"Rooms were clean, front guy was very nice let us check in early since our electric was off for the last day. Very cold nice room."

SpringHill Suites by Marriott San Antonio Medical Center/NW

10/10 Excellent

"We had a great stay! The hotel was very clean, comfortable, and well maintained. Everything was nice and welcoming, and we were very pleased with our room and overall experience. We would definitely stay here again and recommend it to others!"

Courtyard by Marriott Medical Center San Antonio

10/10 Excellent

"Property was in a great location and back off the roadway, so it was quiet. The room was big and clean. Bed was comfortable and ac worked great. Staff was very nice and polite."

Frequently asked questions

What's the area like around South Texas Medical Center?

South Texas Medical Center is located in a walkable area of San Antonio known for its stunning river views and cycling. If you're looking for a convenient place to stay, take a look at the 34 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to South Texas Medical Center?

Courtyard by Marriott Medical Center San Antonio is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from South Texas Medical Center. Other good options close by include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Park Inn by Radisson, Medical Center.

How many hotels should I expect to find close to South Texas Medical Center?

Expedia has 34 hotels and other accommodation options within a mile from South Texas Medical Center.

If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near South Texas Medical Center.

What can I see and do near South Texas Medical Center?

You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre and Laugh Out Loud Comedy Club if you're interested in local theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.

Hotels near South Texas Medical Center

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Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. Courtyard by Marriott Medical Center San Antonio

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. The Westin San Antonio North

6. Park Inn by Radisson, Medical Center

7. Studio 6 San Antonio, Tx - Northwest Medical Center

8. OYO Inn & Suites Medical Center San Antonio

9. Atria Inn & Suites

10. Motel 6 San Antonio, TX - Fiesta Trails

11. Flex Studios

12. Motel 6 San Antonio, TX - Northwest Medical Center

13. Drury Inn & Suites Near La Cantera Parkway

14. Embassy Suites by Hilton San Antonio Landmark

15. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

16. Doubletree By Hilton San Antonio Northwest

17. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

18. Estancia del Norte San Antonio, Tapestry Collection by Hilton

19. Home2 Suites by Hilton San Antonio Airport, TX

20. Embassy Suites by Hilton San Antonio Airport

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

Fairfield Inn & Suites by Marriott San Antonio Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Homewood Suites by Hilton San Antonio Northwest

Drury Inn & Suites San Antonio Northwest Medical Center

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Hyatt Place San Antonio-Northwest/Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

SpringHill Suites by Marriott San Antonio Medical Center/NW

Courtyard by Marriott Medical Center San Antonio

Frequently asked questions