A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Find St. Charles Spa Hotels from S$221

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Check availability on St. Charles Hotels with Spa

Tonight
12 Oct - 13 Oct
Tomorrow
13 Oct - 14 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for St. Charles hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bakery display case with various pastries and cakes.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
S$289
includes taxes & fees
13 Oct - 14 Oct
Ameristar Casino Resort and Spa
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
S$261
includes taxes & fees
13 Oct - 14 Oct
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
S$221
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
S$866
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

5. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
S$561
includes taxes & fees
13 Oct - 14 Oct
Four Seasons Hotel St Louis
View all properties

Choose what matters most at spa hotels in St. Charles

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent
"Extremely comfortable and clean, friendly staff easy to get in and out of convenient to many stores and restaurants"
Matt 2-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis St. Charles
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"I love the place. Clean. Staff are friendly & the location is perfect. It’s close to everything. We will comeback again. ❤️"
Cherry 1-night trip
Posted 10 hours ago
Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"It's a nice hotel that is very convenient for visiting the Arch."
Bradley 1-night trip
Posted 13 hours ago
Drury Plaza Hotel St. Louis at the Arch
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Loved the nightly snack and drink. Breakfast was great as well"
Tyler 3-night trip
Posted 13 hours ago
Embassy Suites by Hilton St. Louis St. Charles
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"friendly staff, great for kids"
Samantha 2-night trip
Posted 18 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Wonderful stay for a small bachelorette party. Had a wonderful time!"
Kara 1-night trip
Posted 2 days ago
Ameristar Casino Resort and Spa

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 178 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have some spare time during your trip, you might want to check out St Charles Convention Center and Ameristar Casino St. Charles.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

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