⭐ Top 10 Hotels Near St. Louis Science Center for 2026

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Our top choices for St. Louis Science Center hotels

A swimming pool with a 40 ft depth marker, lounge chairs, and a brick wall.

A Drury Inn & Suites building with a brick facade, multiple windows, and a parking lot with several cars.

A hotel room with two beds, a chair, a lamp, and a heater.

A spacious kitchen with granite countertops, wooden cabinets, stainless steel appliances, and pendant lighting.

1. Drury Inn & Suites St. Louis Forest Park

2 km from St. Louis Science Center

Tammy

S$202

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A snack and treat display with various products, including chips and beverages, in a store setting.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

2. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 1 km from St. Louis Science Center

Melissa

S$209

includes taxes & fees

28 Oct - 29 Oct

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

A grand lobby with a central seating area, a staircase, and a decorative ceiling.

A bar area with a marble counter, bar stools, and a variety of liquor bottles.

An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.

3. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 1.8 km from St. Louis Science Center

Kristina

S$280

includes taxes & fees

15 Nov - 16 Nov

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern living room with a fireplace, comfortable seating, and a large TV.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

A hotel with a modern facade, large windows, and a sign reading "AC HOTEL CENTRAL WEST END".

4. AC Hotel St. Louis Central West End

Central West End, 1.8 km from St. Louis Science Center

Janice

S$217

includes taxes & fees

20 Nov - 21 Nov

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A modern bar area with a long counter, bar stools, and a television mounted on the wall.

A group of people sitting on a couch in a well-lit room with a large plant and a floor lamp.

A modern cafe interior with a bar area, seating, and a menu board.

5. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.7 km from St. Louis Science Center

Lydia

S$217

includes taxes & fees

25 Oct - 26 Oct

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A reception area with a Christmas tree, a neon sign, and a Santa Claus figure.

A spacious lobby with grey sofas, wooden coffee tables, and potted plants.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

6. The West End

Central West End, 2.3 km from St. Louis Science Center

Trevor

S$170

includes taxes & fees

8 Nov - 9 Nov

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A hotel coffee shop with a coffee machine, mugs, and a buffet area.

A modern indoor seating area with a sofa, tables, and chairs.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

7. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.9 km from St. Louis Science Center

MARY

S$232

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

8. DoubleTree by Hilton St. Louis Forest Park

Central West End, 1.3 km from St. Louis Science Center

Loleta

S$224

includes taxes & fees

1 Nov - 2 Nov

A spacious foyer with a grand staircase, a piano, and a large rug.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

9. White House at Grand Central

3 km from St. Louis Science Center

Mark

S$158

includes taxes & fees

26 Oct - 27 Oct

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A bedroom with a bed, a mirror, a dresser, and a chandelier.

A room with a grand piano, a round table with a red and white tablecloth, and a statue of a robed figure.

10. Central West End B&B

Central West End, 3 km from St. Louis Science Center

Stacee

S$223

includes taxes & fees

29 Oct - 30 Oct

A hotel room with two beds, a chair, a desk, and a large window.

A bathroom with a bathtub, toilet, and sink.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

A lobby with seating areas, a reception desk, and a view through glass doors.

11. Forest Park Hotel by MDR

The Hill, 1.8 km from St. Louis Science Center

Kevan

S$121

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.

A Red Roof Plus hotel with a stone facade, a parking lot, and a covered outdoor area.

A Red Roof Plus hotel lobby with two leather chairs, a coffee station, and a sign indicating free Wi-Fi in all rooms.

A wooden surface with a metal rod and a power outlet with a red plug-in sign.

12. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.8 km from St. Louis Science Center

Sean

S$112

includes taxes & fees

25 Oct - 26 Oct

A room with a green armchair, a round table, a lamp, and a mirror on the wall.

A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

A two-story building with a dark entrance, large windows, and a brick facade.

A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

13. Truitt Hotel

Lafayette Square, 4.9 km from St. Louis Science Center

Gabrielle

S$261

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

14. Pear Tree Inn St. Louis Airport

15 km from St. Louis Science Center

Curtiss

S$137

includes taxes & fees

26 Oct - 27 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A spa bath with a sign indicating a capacity of 8 persons.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

15. Drury Plaza Hotel St. Louis Brentwood

6.5 km from St. Louis Science Center

angelia

S$194

includes taxes & fees

1 Nov - 2 Nov

A hallway with framed artwork on the walls and a poster advertising an event.

A red brick building with a gabled roof and arched windows.

A dining table set with plates, a pitcher, and a fruit bowl.

A bedroom with a wooden bed, blue walls, and a white door.

16. Benton Park Inn

Benton Park, 5.5 km from St. Louis Science Center

Lindsay

S$205

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with a glass facade, seating area, and a staircase.

A couple relaxing by a window overlooking a bridge and water.

A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

17. Four Seasons Hotel St Louis

7.5 km from St. Louis Science Center

Nicole

S$560

includes taxes & fees

25 Oct - 26 Oct

A log cabin with a stone chimney, a porch with a stone railing, and a staircase leading to the entrance.

A stone fireplace with a wooden mantel, surrounded by rustic decor and a wooden ceiling.

A rustic wooden interior with a wooden bench displaying various animal carvings and a stone wall.

A cozy bedroom with a stone fireplace, a bed with a patterned bedspread, and a television on a wooden stand.

18. The Lodge at Grant's Trail

10.1 km from St. Louis Science Center

Sherri

S$261

includes taxes & fees

27 Oct - 28 Oct

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

A hotel room with two beds, a desk, and a chair.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

19. The Knight Center at Washington University

4.3 km from St. Louis Science Center

Rosalyn

S$212

includes taxes & fees

19 Nov - 20 Nov

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.

A large hotel with a prominent "RIVER CITY" sign.

20. River City Casino & Hotel

11 km from St. Louis Science Center

jodi

S$168

includes taxes & fees

4 Nov - 5 Nov

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Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,023 reviews	View
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,000 reviews	View
The Royal Sonesta Chase Park Plaza St. Louis	9.2 Wonderful 1,010 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 858 reviews	View
Hotel Indigo St Louis - Central West End by IHG	8.8 Excellent 1,000 reviews	View

Hotels recommended for families near St. Louis Science Center

DoubleTree by Hilton St. Louis Forest Park

Central West End

S$224

includes taxes & fees

1 Nov - 2 Nov

Home2 Suites by Hilton St. Louis/Forest Park

The Grove

S$232

includes taxes & fees

25 Oct - 26 Oct

Hotel Indigo St Louis - Central West End by IHG

Central West End

S$217

includes taxes & fees

25 Oct - 26 Oct

The Royal Sonesta Chase Park Plaza St. Louis

Central West End

S$280

includes taxes & fees

15 Nov - 16 Nov

Hampton Inn & Suites St. Louis at Forest Park

Dogtown

S$209

includes taxes & fees

28 Oct - 29 Oct

Drury Inn & Suites St. Louis Forest Park

Clifton Heights

S$202

includes taxes & fees

1 Nov - 2 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

An outdoor patio area with a pool, red umbrellas, and seating arrangements.

A restaurant with a central bar area, seating arrangements, and a fireplace.

A modern building with a unique, curved roof structure.

The Cheshire

Richmond Heights

S$225

includes taxes & fees

1 Nov - 2 Nov

AC Hotel St. Louis Central West End

Central West End

S$217

includes taxes & fees

20 Nov - 21 Nov

Top St. Louis Science Center Hotel Reviews

DoubleTree by Hilton St. Louis Forest Park

8/10 Good

"The staff were very helpful but the breakfast buffet was a little overpriced for what you get. The beds were also very soft which most people would probably find nice but, if you have back problems like I do, may be too soft and made it hard to sleep. If you need firmer mattresses like I do, it might be better to sleep on the floor. The parking garage was very cramped as well and could barely even get into the spaces due to their width."

Moonrise Hotel

10/10 Excellent

"Very friendly staff and we loved the rooftop bar."

The West End

10/10 Excellent

"E Z check in. Hotel was clean and proper. Location was excellent. Secured parking lot. Spotless room and hotel."

Home2 Suites by Hilton St. Louis/Forest Park

10/10 Excellent

"Very clean room staff was awesome. Recommend."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Exceeded our expectations."

Hotel Indigo St Louis - Central West End by IHG

8/10 Good

"The elevator is extremely small. Only suggestion I would give is there should be more elevators in the bed sits extremely low to the ground. But overall, the place was clean, and my vehicle was safe."

AC Hotel St. Louis Central West End

10/10 Excellent

"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

10/10 Excellent

"Staff was"

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.

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A stone fountain with water cascading down a tiered structure, surrounded by a pond and a grassy area with a building in the background.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot.

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A theater stage with a variety of neon signs advertising different businesses.

The Muny Theater

8.6/10 (7 reviews)

You can get tickets for a performance at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

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Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game.

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Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 74 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.

How many hotels should I expect to find close to St. Louis Science Center?

Expedia has 74 hotels and other accommodation options within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and St. Louis Symphony Orchestra.

Hotels near St. Louis Science Center

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for St. Louis Science Center hotels

1. Drury Inn & Suites St. Louis Forest Park

2. Hampton Inn & Suites St. Louis at Forest Park

3. The Royal Sonesta Chase Park Plaza St. Louis

4. AC Hotel St. Louis Central West End

5. Hotel Indigo St Louis - Central West End by IHG

6. The West End

7. Home2 Suites by Hilton St. Louis/Forest Park

8. DoubleTree by Hilton St. Louis Forest Park

9. White House at Grand Central

10. Central West End B&B

11. Forest Park Hotel by MDR

12. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

13. Truitt Hotel

14. Pear Tree Inn St. Louis Airport

15. Drury Plaza Hotel St. Louis Brentwood

16. Benton Park Inn

17. Four Seasons Hotel St Louis

18. The Lodge at Grant's Trail

19. The Knight Center at Washington University

20. River City Casino & Hotel

Compare popular hotels close to St. Louis Science Center

Hotels recommended for families near St. Louis Science Center

DoubleTree by Hilton St. Louis Forest Park

Home2 Suites by Hilton St. Louis/Forest Park

Hotel Indigo St Louis - Central West End by IHG

The Royal Sonesta Chase Park Plaza St. Louis

Hampton Inn & Suites St. Louis at Forest Park

Drury Inn & Suites St. Louis Forest Park

The Cheshire

AC Hotel St. Louis Central West End

Top St. Louis Science Center Hotel Reviews

DoubleTree by Hilton St. Louis Forest Park

Moonrise Hotel

The West End

Home2 Suites by Hilton St. Louis/Forest Park

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Hotel Indigo St Louis - Central West End by IHG

AC Hotel St. Louis Central West End

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions