A modern building with a unique triangular roof and a central spire.

Hotels in Santa Lucia

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Lucia hotels

A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

1. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (702 reviews)
"We enjoyed our stay"
United States
Anna
The price is S$116
includes taxes & fees
1 Nov - 2 Nov
Grande Albergo Alfeo
A hotel room with a large bed, a chair, a small table, and a chandelier.

2. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (46 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is S$166
includes taxes & fees
21 Oct - 22 Oct
Hotel Palazzo Cavalieri
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

3. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (292 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is S$122
includes taxes & fees
31 Oct - 1 Nov
Nostos rooms & Apartments
A neatly made bed with a dark quilt, white pillows, and a beige headboard. There are two bedside lamps on either side of the bed.

4. Melody rooms

Melody rooms
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
The price is S$55
includes taxes & fees
16 Oct - 17 Oct
Melody rooms
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

5. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (299 reviews)
"Staff was very friendly and helpful"
Canada
Dena
The price is S$266
includes taxes & fees
29 Oct - 30 Oct
Caportigia Boutique Hotel
A balcony with wicker chairs and a glass table overlooking a marina with boats.

6. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (43 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is S$234
includes taxes & fees
1 Nov - 2 Nov
Fortaleza Charme House
A modern dining area with a white table, green chairs, and a potted plant.

7. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (10 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is S$165
includes taxes & fees
2 Nov - 3 Nov
San Nicola Rooms Siracusa
A modern bedroom with a bed, bedside table, and a unique feature of a table with a fire effect.

8. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is S$93
includes taxes & fees
11 Oct - 12 Oct
B&B IL MORO
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.

9. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (78 reviews)
"The location of this place is amazing and that balcony view iconic. Staff super helpful too."
Canada
Marsel
The price is S$142
includes taxes & fees
2 Nov - 3 Nov
Lakkios
A balcony with a table set for two, a chair, and a view of a building with multiple windows and balconies.

10. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (92 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is S$109
includes taxes & fees
2 Nov - 3 Nov
B&B Nike
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.

11. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (43 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is S$85
includes taxes & fees
20 Oct - 21 Oct
Gymnasium
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.

12. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (18 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is S$198
includes taxes & fees
2 Nov - 3 Nov
Calafatari B&B
A woman in a black swimsuit sitting in a hot tub overlooking a beach with a clear sky and the sun shining.

13. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is S$370
includes taxes & fees
4 Oct - 5 Oct
Re Dionisio Luxury Suites
A balcony with potted plants and a metal railing.

14. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (387 reviews)
"Fantastic breakfast, great cakes and good coffee. The rooms were comfortable and the location is great for all the important places to be in Siracusa. It was quiet and peaceful and the staff were helpful and friendly."
United Kingdom
Richard
The price is S$80
includes taxes & fees
29 Oct - 30 Oct
Piccolo Hotel Casa Mia
A terrace with white tables and chairs, white umbrellas, and a view of the sea.

15. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (132 reviews)
"We had an amazing time. Sabrina and Claudia were wonderful. The place is top notch in everything they do. The food was so fresh and delicious . I was sad when i had to leave them. High praise for this hotel. The views breath taking."
United States
Duane
The price is S$286
includes taxes & fees
2 Nov - 3 Nov
Giuggiulena Villa
A bedroom with a stone wall, a bed with a wooden headboard, a tray with a plant, and a window with curtains.

16. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is S$105
includes taxes & fees
2 Nov - 3 Nov
B&B Siracusa
A bedroom with a bed, a desk, a chair, a television, and a mirror.

17. Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (20 reviews)
"Hotel was perfect for our 5 day stay,great location within walking distance to supermarkets and city centre. Antonino was a great host and provided clear communication for checking in and any questions about the place. Would highly recommend and visit again in the future."
Italy
Nello
The price is S$163
includes taxes & fees
7 Oct - 8 Oct
Fortuna Guest House
A hot tub with a view of a marina.

18. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.8 out of 10, Excellent, (3 reviews)
"This was one of the best hotel stays I’ve ever had. Simply, you won’t be disappointed from location, excellent service and the most helpful and welcoming staffs. Highly recommended"
United States
Hossein
The price is S$382
includes taxes & fees
31 Oct - 1 Nov
Casa Miranda Boutique
A rooftop lounge area with lounge chairs and a large potted plant.

19. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is S$108
includes taxes & fees
31 Oct - 1 Nov
Le Camere Luxsury Rooms
A balcony with a table set for tea, a book, and a view of a building and water.

20. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (125 reviews)
"Very friendly and helpful staff."
United States
David
The price is S$137
includes taxes & fees
17 Oct - 18 Oct
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
299 reviews
View
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.
Lakkios
3.0 star property
9.2
Wonderful
78 reviews
View
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
292 reviews
View
A hotel room with a large bed, a chair, a small table, and a chandelier.
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
46 reviews
View
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.
Gymnasium
3.0 star property
8.8
Excellent
43 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

A natural rock arch over a body of water with people paddling in kayaks.
Photo by Salvo Cannizzaro
Open Photo by Salvo Cannizzaro

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

10/10 Excellent
"Very responsive staff that helped me organize transportation to and from the airport, accommodation for my baby, and a surprise welcome for my wife’s birthday. Amazing location just outside Ortigia, I honestly preferred staying there than on the island. Highly recommended."
Diego 4-night trip
Posted 3 hours ago
Hotel Palazzo Cavalieri

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 313 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Explore a world of travel with Expedia