A modern building with a unique triangular roof and a central spire.

Hotels in Santa Lucia

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Lucia hotels

Coffee/tea maker, electric kettle

1. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (285 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is S$110
includes taxes & fees
4 Sept - 5 Sept
Nostos rooms & Apartments
Balcony

2. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is S$115
includes taxes & fees
11 Sept - 12 Sept
B&B Nike
Rooftop terrace

3. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (289 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is S$296
includes taxes & fees
27 Aug - 28 Aug
Caportigia Boutique Hotel
Front of property

4. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (688 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is S$196
includes taxes & fees
24 Aug - 25 Aug
Grande Albergo Alfeo
Minibar, in-room safe, desk, soundproofing

5. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is S$171
includes taxes & fees
23 Aug - 24 Aug
Lakkios
Porch

6. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is S$109
includes taxes & fees
31 Aug - 1 Sept
Piccolo Hotel Casa Mia
Free WiFi

7. B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is S$99
includes taxes & fees
23 Aug - 24 Aug
B&B L'INFIORESCENZA
Premium bedding, desk, cots/infant beds, rollaway beds

8. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is S$126
includes taxes & fees
27 Aug - 28 Aug
B&B Siracusa
In-room safe, desk, soundproofing, iron/ironing board

9. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is S$212
includes taxes & fees
23 Aug - 24 Aug
B&B IL MORO
Terrace/patio

10. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (37 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is S$285
includes taxes & fees
23 Aug - 24 Aug
Fortaleza Charme House
View from room

11. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is S$102
includes taxes & fees
11 Sept - 12 Sept
Gymnasium
Free daily buffet breakfast

12. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is S$197
includes taxes & fees
11 Sept - 12 Sept
San Nicola Rooms Siracusa
Soundproofing, free WiFi

13. Melody rooms

Melody rooms
Santa Lucia
The price is S$58
includes taxes & fees
27 Aug - 28 Aug
Melody rooms
Lobby lounge

14. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is S$127
includes taxes & fees
5 Sept - 6 Sept
Regina Margherita
Terrace/patio

15. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is S$148
includes taxes & fees
13 Aug - 14 Aug
Le Camere Luxsury Rooms
View from room

16. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is S$162
includes taxes & fees
23 Aug - 24 Aug
Hotel Mediterraneo
In-room safe, soundproofing, iron/ironing board (on request), free WiFi

17. Isonzo Suites

Isonzo Suites
Santa Lucia
9.0 out of 10, Wonderful, (7 reviews)
"."
Italy
Gianluca
The price is S$157
includes taxes & fees
11 Sept - 12 Sept
Isonzo Suites
Soundproofing, free WiFi

18. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is S$199
includes taxes & fees
30 Aug - 31 Aug
Hotel Palazzo Cavalieri
View from room

19. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is S$228
includes taxes & fees
13 Aug - 14 Aug
Calafatari B&B
Frette Italian sheets, premium bedding, down duvets, desk

20. Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (19 reviews)
"The owner was really nice and helpful! Really enjoyed our stay here."
Finland
Kirsi
The price is S$131
includes taxes & fees
8 Sept - 9 Sept
Fortuna Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
289 reviews
View
Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
285 reviews
View
Soundproofing, free WiFi
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
44 reviews
View
1 bedroom, down duvets, minibar, in-room safe
Re Dionisio Luxury Suites
3.0 star property
8.8
Excellent
58 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Aerial view of Ortigia, historical centre of the city of Syracuse. Aerial view of Maniace fortress in Ortigia, Sicily, Italy. Sanctuary "Our Lady of Tears" is at the background

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Top Santa Lucia Hotel Reviews

Mangia's Brucoli, Sicily, Autograph Collection

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent
"Beautiful Place !!!"
Devorah 7-night trip
Posted 3 days ago
Mangia's Brucoli, Sicily, Autograph Collection

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels will I find in Santa Lucia?
Expedia has 311 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Explore a world of travel with Expedia