⭐ Top 10 Hotels Near University of Chicago Medicine for 2026

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Our top choices for University of Chicago Medicine hotels

A modern hotel room with large windows, a sofa, chairs, a dining table, and a coffee table.

A spacious living area with a modern chandelier, comfortable seating, and a fireplace.

A bar area with a marble countertop, multiple shelves of bottles, and a large TV screen. There are several bar stools and a round table with a vase of flowers.

An outdoor seating area with sofas, chairs, and tables, surrounded by trees and string lights.

1. Sophy Hyde Park

Hyde Park, 1.6 km from University of Chicago Medicine

amy

S$409

includes taxes & fees

1 Nov - 2 Nov

An outdoor café with tables and chairs, a red umbrella, and a flower-lined walkway.

A hotel room with a bed, a desk, a chair, a sofa, a coffee table, and a painting on the wall.

A modern multi-story building with a prominent central tower, large windows, and a pedestrian walkway.

A modern lounge area with a fireplace, comfortable seating, and a large window.

2. Hyatt Place Chicago-South/University Medical Center

Hyde Park, 1.8 km from University of Chicago Medicine

Denise

S$299

includes taxes & fees

2 Nov - 3 Nov

A hotel room with a large bed, a desk, a chair, a nightstand, a lamp, and a mirror.

A row of parked cars along a tree-lined street with multi-story buildings in the background.

3. Chicago Lake Shore Hotel

2.5 km from University of Chicago Medicine

Princets

S$203

includes taxes & fees

1 Nov - 2 Nov

A room with large windows, a wooden floor, and a built-in air conditioning unit.

A hotel room with a large bed, a wooden headboard, a patterned bedspread, and a view through an open door to another room.

4. Best Motel By OYO Chicago I-90

1.7 km from University of Chicago Medicine

Saul

S$123

includes taxes & fees

19 Oct - 20 Oct

A spacious kitchen with white cabinetry, a central island with bar stools, pendant lighting, and a large window with a view.

A spacious room with hardwood flooring, a stone fireplace, a door with glass panels, and a vase on the floor.

A living room with a fireplace, a sofa, a coffee table, and a TV mounted on the wall.

A modern kitchen with white cabinetry, stainless steel appliances, and a wooden dining table with benches.

5. The Sono Chicago

13.6 km from University of Chicago Medicine

Christie

S$360

includes taxes & fees

13 Oct - 14 Oct

A modern indoor pool area with lounge chairs, a wooden table, and large windows.

A modern hotel room with a large bed, a desk, a chair, a TV, and a sliding door leading to a shower area.

A modern hotel lobby with a reception desk, seating area, and artwork on the walls.

A modern hotel with multiple floors, a covered entrance, and a parking lot.

6. Hampton Inn & Suites Chicago Medical District UIC

11.2 km from University of Chicago Medicine

Bobby

S$230

includes taxes & fees

25 Oct - 26 Oct

A high-rise hotel with multiple floors, large windows, and a prominent Tiffany & Co. store on the ground level.

A spacious hotel lobby with multiple seating areas, a grand staircase, and large windows offering views of the city.

A modern indoor pool area with large windows, potted palm plants, and lounge chairs.

A modern bar area with a checkered floor, bar stools, and a bartender.

7. The Peninsula Chicago

Streeterville, 12 km from University of Chicago Medicine

Levi

S$950

includes taxes & fees

1 Nov - 2 Nov

A cityscape with a river, a bridge, and a dining area with tables and chairs.

A modern hotel room with large floor-to-ceiling windows offering a city view.

A modern hotel room with large windows, white furniture, and a view of tall buildings.

A high-rise hotel with a prominent 'TRUMP' sign, reflecting in the water, surrounded by other tall buildings.

8. Trump International Hotel & Tower Chicago

River North, 11.3 km from University of Chicago Medicine

Mark

S$701

includes taxes & fees

1 Nov - 2 Nov

A couple dining at a table with a view of a cityscape and a sunset.

A modern hotel room with a large bed, a seating area, a TV, and a view of the city and ocean.

A rooftop terrace with a dining table, chairs, and a view of the cityscape, including the Water Tower Place building.

A modern living room with a sofa, chairs, a coffee table, and a TV. A large window offers a view of a cityscape and a tower.

9. Park Hyatt Chicago

Streeterville, 12.1 km from University of Chicago Medicine

Tom

S$825

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with a spiral staircase, seating areas, and large windows offering city views.

A modern interior with a spiral staircase, large windows, and a geometric patterned floor.

A high-rise building with a modern glass facade, surrounded by other tall buildings.

A modern living room with a large sectional sofa, a flat-screen TV mounted on the wall, a dining area with a table and chairs, and a view of the cityscape through large windows.

10. Residence Inn Chicago Downtown Magnificent Mile

Streeterville, 11.8 km from University of Chicago Medicine

Brian

S$334

includes taxes & fees

1 Nov - 2 Nov

A restaurant with tables and chairs arranged in a corridor, large windows, and hanging lamps.

A rooftop pool area with city views, two lounge chairs, and a small table with a vase.

A dining area with wicker chairs and tables, overlooking a marina with boats and a Ferris wheel.

A modern hotel entrance with a prominent "STREGIS" sign, large glass windows, and a well-lit facade.

11. The St. Regis Chicago

11 km from University of Chicago Medicine

Xiomara

S$951

includes taxes & fees

29 Oct - 30 Oct

The Riu Plaza Chicago Hotel facade with a grand entrance, large windows, and a modern architectural design.

A modern hotel lobby with a central seating area, a reception desk, and a decorative wall with a unique design.

A spacious lobby with a marble floor, a reception desk, and a glass partition.

A couple dining at a table with a city view, surrounded by chairs and a variety of dishes.

12. Hotel Riu Plaza Chicago

Streeterville, 11.7 km from University of Chicago Medicine

Denys

S$280

includes taxes & fees

2 Nov - 3 Nov

A spacious bar area with high ceilings and large windows, offering views of a cityscape.

A hotel room with a bed, a sofa with cushions, a large window with a view of a cityscape and water.

A cityscape with modern high-rise buildings, a river, and a boat.

A multi-level hotel lobby with a glass elevator, a seating area, and a dining space.

13. Hyatt Regency Chicago

The Loop, 11.1 km from University of Chicago Medicine

Mark

S$421

includes taxes & fees

31 Oct - 1 Nov

A rooftop terrace with a city skyline view, featuring a mix of modern and classic architecture, and several potted plants.

A modern staircase with glass railings and pendant lighting.

A modern hotel room with a green sofa, two round tables, a city view, and a chandelier.

A modern hotel lobby with a reception desk, seating area, staircase, and large windows.

14. The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago

Streeterville, 11.5 km from University of Chicago Medicine

Jessica

S$773

includes taxes & fees

30 Oct - 31 Oct

A black luxury car parked in front of a hotel entrance with a glass canopy decorated with festive ornaments.

An indoor swimming pool with a modern design, a reception area with a sign for Waldorf Astoria Chicago, and a seating area with two people.

A bar area with a long counter, multiple stools, and a seating area with a booth.

A couple dining on a balcony with a cityscape view.

15. Waldorf Astoria Chicago

12.5 km from University of Chicago Medicine

Luis

S$844

includes taxes & fees

1 Nov - 2 Nov

A modern indoor swimming pool with a clear blue water surface, a wooden ceiling, and a wall with a floral pattern.

A rooftop terrace with a view of a city skyline at dusk.

A modern hotel room with a large window offering a city view, a wooden desk with a laptop, and a small seating area.

A modern hotel room with a large window, a wooden desk, a bathroom with a mirror, and a view of the cityscape.

16. Nobu Hotel Chicago

11.3 km from University of Chicago Medicine

Abhay

S$723

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, a wooden cabinet, a chair, and a view of the city skyline.

A modern dining area with a round table and chairs, large windows with a city view, and a decorative light fixture.

A rooftop pool with lounge chairs and a city skyline in the background.

17. Viceroy Chicago

12.8 km from University of Chicago Medicine

Margaret

S$489

includes taxes & fees

1 Nov - 2 Nov

A person sitting by a window with a view of a cityscape, including a tall tower.

An indoor swimming pool with a skylight, a lifeguard chair, and a potted plant.

A couple walking through a spacious lobby with marble flooring, large white floral arrangements, and a modern staircase in the background.

A modern bar area with a central bar and multiple stools, surrounded by a high ceiling with a decorative light fixture.

18. Four Seasons Hotel Chicago

Streeterville, 12.4 km from University of Chicago Medicine

Teresa

S$798

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a fire feature, seating, and a bar.

A group of people seated at a table with drinks and a salad, in a modern indoor setting with large windows and a bar area.

An outdoor terrace with a fire feature, seating, and a city view.

A modern lobby with a reception desk, seating area, and elevators.

19. Hyatt Place Chicago/Wicker Park

14.5 km from University of Chicago Medicine

Tyler

S$299

includes taxes & fees

1 Nov - 2 Nov

A street view with outdoor seating, a building with a sign, and tall skyscrapers in the background.

A dining area with a long table, chairs, and a fireplace. There are framed pictures on the walls and a large flat-screen TV mounted on the wall.

A bar with three wooden shelves filled with bottles and glasses.

A lobby with a checkered floor, seating area, and a glass entrance.

20. The Talbott, Autograph Collection

12.4 km from University of Chicago Medicine

Karina

S$409

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to University of Chicago Medicine

Property	Property class	Guest rating
Sophy Hyde Park	9.4 Exceptional 1,001 reviews	View
Hyatt Place Chicago-South/University Medical Center	8.8 Excellent 1,001 reviews	View
Chicago Lake Shore Hotel	7.0 Good 1,002 reviews	View
Best Motel By OYO Chicago I-90	3.4 147 reviews	View
The Sono Chicago	10.0 Exceptional 564 reviews	View

Top University of Chicago Medicine Hotel Reviews

Jaslin Hotel

10/10 Excellent

"The room was very spacious and clean. Definitely better than I expected for a 3-star hotel. Also the soaps in the bathroom were very nice quality. Convenient location to access the trains and the Uber/Lyft drop-off/pickup spot was very convenient in front of the main entrance to the hotel. I would definitely stay here again."

Chinatown Hotel Chicago

10/10 Excellent

"Great place for a peace of mind beautiful area everything you can think is in walking distance"

Hilton Garden Inn Chicago McCormick Place

10/10 Excellent

"Great room for the right price"

SpringHill Suites by Marriott Chicago Chinatown

10/10 Excellent

"Room was clean, spacious bathroom. Breakfast was great."

Chicago Lake Shore Hotel

10/10 Excellent

"Very closed to the Places we were visiting"

Home2 Suites by Hilton Chicago McCormick Place

10/10 Excellent

"It is a triple branded Hilton property with several shared spaces. Nice setup to be able to work a show at the attached convention center facilities. Served a light complimentary breakfast."

Villa Dubois Guest House

10/10 Excellent

"Wonderful place"

Mccormick Place Guest House

8/10 Good

"I had a wonderful stay at the DuBois McCormick Place Guest House. The location was very convenient, especially for visiting McCormick Place and exploring the surrounding area. The room was clean, comfortable, and well maintained. I also appreciated the peaceful atmosphere and the overall attention to detail. The guest house offered a comfortable home base after a busy day, with everything needed for a pleasant stay. I would happily recommend the DuBois McCormick Place Guest House to both business and leisure travelers, and I look forward to staying there again."

McCormick Suites by Slumber Stay

10/10 Excellent

"It was an above-average stay."

Frequently asked questions

What's the area like around University of Chicago Medicine?

University of Chicago Medicine is located in a vibrant area of Chicago known for its beautiful lakeside setting and stunning architecture. If you're looking for a convenient place to stay, take a look at the 78 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near University of Chicago Medicine?

Sophy Hyde Park is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a fitness centre. It's located 1 mi (1.6 km) from University of Chicago Medicine. Other good choices within 5 miles include Chicago Lake Shore Hotel and Best Motel By OYO Chicago I-90.

How many hotels are there close to University of Chicago Medicine?

Expedia has 78 hotels and other accommodation options within a mile from University of Chicago Medicine.

If I need to cancel the hotel reservation for my stay near University of Chicago Medicine, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best options available near University of Chicago Medicine.

What can I see and do near University of Chicago Medicine?

You might want to spend some time browsing the exhibits at Griffin Museum of Science and Industry, DuSable Black History Museum and Education Center or Stony Island Arts Bank. Explore landmarks like Barack Obama Residence, Wabash Ave YMCA and Ida B Wells House. You can watch performances at Arie Crown Theater, Radius - Chicago and Court Theatre if you're interested in local theatre.

How can I get to University of Chicago Medicine?

If you'd like to explore more of the area, jump aboard a train from Chicago 55th-56th-57th Street Station, Chicago 59th Street Station or Chicago 51st-53rd Street Station (Hyde Park). There might not be many public transport options to choose from close to University of Chicago Medicine so consider a car rental to maximise your time.

Hotels near University of Chicago Medicine

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for University of Chicago Medicine hotels

1. Sophy Hyde Park

2. Hyatt Place Chicago-South/University Medical Center

3. Chicago Lake Shore Hotel

4. Best Motel By OYO Chicago I-90

5. The Sono Chicago

6. Hampton Inn & Suites Chicago Medical District UIC

7. The Peninsula Chicago

8. Trump International Hotel & Tower Chicago

9. Park Hyatt Chicago

10. Residence Inn Chicago Downtown Magnificent Mile

11. The St. Regis Chicago

12. Hotel Riu Plaza Chicago

13. Hyatt Regency Chicago

14. The Gwen, a Luxury Collection Hotel, Michigan Avenue Chicago

15. Waldorf Astoria Chicago

16. Nobu Hotel Chicago

17. Viceroy Chicago

18. Four Seasons Hotel Chicago

19. Hyatt Place Chicago/Wicker Park

20. The Talbott, Autograph Collection

Compare popular hotels close to University of Chicago Medicine

Top University of Chicago Medicine Hotel Reviews

Jaslin Hotel

Chinatown Hotel Chicago

Hilton Garden Inn Chicago McCormick Place

SpringHill Suites by Marriott Chicago Chinatown

Chicago Lake Shore Hotel

Home2 Suites by Hilton Chicago McCormick Place

Villa Dubois Guest House

Mccormick Place Guest House

McCormick Suites by Slumber Stay

Frequently asked questions