Best Western, Upstate South Carolina hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Top Upstate South Carolina Best Western Hotels

Best Western Greenville Airport Inn
Best Western Greenville Airport Inn
7.8 out of 10, Good, (1001)
The price is S$107
includes taxes & fees
7 Jul - 8 Jul

Best Western Spartanburg Northwest
Best Western Spartanburg Northwest
8.2 out of 10, Very good, (753)
The price is S$121
includes taxes & fees
8 Jul - 9 Jul

Best Western Travelers Rest Greenville
Best Western Travelers Rest Greenville
7.8 out of 10, Good, (1001)
The price is S$136
includes taxes & fees
13 Jul - 14 Jul

Best Western Seneca-Clemson
Best Western Seneca-Clemson
8.4 out of 10, Very good, (592)
The price is S$125
includes taxes & fees
19 Jul - 20 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent Reviews in Upstate South Carolina
Recent Reviews in Upstate South Carolina

Hyatt Regency Greenville
5/5 Excellent
"We had a great time! The facility was nice, and the staff—except for security—were very kind and helpful. My kids and I truly enjoyed our stay, especially being within walking distance of everything including downtown Greenville. There was a bridge tournament and a few baseball teams in town for a tournament, which made it feel lively but not overcrowded.
Overall, we had a wonderful experience. Lisa the bartender was especially friendly and personable—she really made us feel welcome. I can’t wait to come back!"
A verified traveller stayed at Hyatt Regency Greenville
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Upstate South Carolina Hotel Brands
More Hotel Options in Upstate South Carolina
- Budget Hotels in Upstate South Carolina
- Business Hotels in Upstate South Carolina
- Family friendly Hotels in Upstate South Carolina
- Golf Hotels in Upstate South Carolina
- Hotels near Shopping Areas in Upstate South Carolina
- Hotels with Air Conditioning in Upstate South Carolina
- Hotels with Airport Shuttle in Upstate South Carolina
- Hotels with Balcony in Upstate South Carolina
- Hotels with Bars / Lounges in Upstate South Carolina
- Hotels with Breakfast in Upstate South Carolina
- Hotels with Entertainment in Upstate South Carolina
- Hotels with Gyms in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels with Internet in Upstate South Carolina
- Hotels with Restaurants in Upstate South Carolina
- Hotels with Spa in Upstate South Carolina
- Hotels with Swimming Pools in Upstate South Carolina
- Hotels with Views in Upstate South Carolina
- Hotels with WiFi in Upstate South Carolina
- Hotels with connecting rooms in Upstate South Carolina
- Hotels with free Internet in Upstate South Carolina
- Hotels with free airport shuttle in Upstate South Carolina
- Hotels with free breakfast in Upstate South Carolina
- Hotels with free parking in Upstate South Carolina
- Hotels with free wifi in Upstate South Carolina
- Hotels with indoor pool in Upstate South Carolina
- Hotels with parking in Upstate South Carolina
- Hotels with shuttle in Upstate South Carolina
- Hotels with smoking rooms in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Pet friendly Hotels in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina