A bench, a bicycle, and a lake surrounded by trees.

Boutique Hotels in Upstate South Carolina

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina Boutique Hotels

Tonight
30 Sept - 1 Oct
Tomorrow
1 Oct - 2 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Upstate South Carolina boutique hotels

1. Hotel Domestique

Hotel Domestique
Travelers Rest
United States
Chuck
S$589
includes taxes & fees
4 Oct - 5 Oct
Hotel Domestique

2. Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
Lakemont
United States
Richard
S$182
includes taxes & fees
11 Oct - 12 Oct
Lake Rabun Hotel & Restaurant

3. Outpost Inn

Outpost Inn
Highlands
United States
Erin
S$284
includes taxes & fees
12 Oct - 13 Oct
Outpost Inn
View all properties

Top Upstate South Carolina Hotel Reviews

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

8/10 Good
"The staff was lovely and the rooms were great nice comfortable bed. We had a really nice view from the window on the fifth floor. The only thing was they were doing renovations which I wasn’t expecting. Other than that everything was great."
Faviola 1-night trip
Posted 8 days ago
Hyatt Place Greenville/Haywood

Explore a world of travel with Expedia