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Hotels in Uptown

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Check prices for these dates

Tonight
23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Uptown hotels

Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
17.7 km from Uptown
8.4 out of 10, Very good, (4033)
"Everything was great!"
United States
Kathryn
The price is S$150
includes taxes & fees
24 Dec - 25 Dec
Hyatt Regency St. Louis at The Arch
Lounge
The Westin St. Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
18.4 km from Uptown
8.6 out of 10, Excellent, (1002)
"Great location "
United States
Gregory
The price is S$191
includes taxes & fees
30 Dec - 31 Dec
The Westin St. Louis
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
17.7 km from Uptown
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is S$157
includes taxes & fees
29 Dec - 30 Dec
Hilton Pennywell St. Louis at the Arch
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
18.3 km from Uptown
9.4 out of 10, Exceptional, (1107)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
The price is S$228
includes taxes & fees
24 Dec - 25 Dec
Live by Loews - St.Louis
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
17.8 km from Uptown
8.8 out of 10, Excellent, (1248)
"The room was spacious, and breakfast was very good with great coffee."
United States
Susan
The price is S$168
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites by Hilton St. Louis Downtown
Lobby
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport, 2.6 km from Uptown
9.6 out of 10, Exceptional, (1001)
"Staff was super friendly and helpful - when i woke up with a sore throat in the middle of thr night, the staff gathered up hit tea and honey for me... cannot ask for a more kind and helpful staff!"
United States
Jamie
The price is S$146
includes taxes & fees
4 Jan - 5 Jan, 2026
Drury Inn & Suites St. Louis Collinsville
Pub
The Knight Center at Washington University

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
27.9 km from Uptown
9.4 out of 10, Exceptional, (448)
"Awesome place to stay!"
United States
james
The price is S$199
includes taxes & fees
28 Dec - 29 Dec
The Knight Center at Washington University
Casino
HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination
4.0 star property
17.2 km from Uptown
6.8 out of 10, (1002)
"It was very convenient for us because it was across from the convention center. "
United States
Helen P
The price is S$205
includes taxes & fees
25 Dec - 26 Dec
HoteLumiere at the Arch - A Caesars Rewards Destination
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
17.5 km from Uptown
8.8 out of 10, Excellent, (1181)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
The price is S$147
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Rooftop bar
Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
4.0 star property
17.9 km from Uptown
8.8 out of 10, Excellent, (469)
"Great hotel. "
United States
Abby
The price is S$237
includes taxes & fees
2 Jan - 3 Jan, 2026
Hotel Saint Louis, Autograph Collection
Exterior
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
2.5 star property
11.9 km from Uptown
8.4 out of 10, Very good, (552)
"Clean rooms and friendly staff"
United States
Heidi
The price is S$146
includes taxes & fees
4 Jan - 5 Jan, 2026
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
Lobby
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
23.7 km from Uptown
9.0 out of 10, Wonderful, (684)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is S$193
includes taxes & fees
28 Dec - 29 Dec
AC Hotel St. Louis Central West End
3 bars/lounges, rooftop bar
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
18 km from Uptown
7.6 out of 10, Good, (1069)
"Clean room, this hotel is great for young people, night activity, 360 rooftop bar always crowded but pretty."
United States
Joan
The price is S$212
includes taxes & fees
29 Dec - 30 Dec
Hilton St. Louis at the Ballpark
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
17.9 km from Uptown
8.8 out of 10, Excellent, (1167)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is S$136
includes taxes & fees
28 Dec - 29 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Indoor pool
Hampton Inn O'Fallon

Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
10.9 km from Uptown
9.2 out of 10, Wonderful, (812)
"Very nice rooms, clean and quiet!"
United States
Michael
The price is S$158
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn O'Fallon
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
30.1 km from Uptown
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
United States
Hannah
The price is S$181
includes taxes & fees
26 Dec - 27 Dec
Le Méridien St. Louis Clayton
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
30 km from Uptown
9.4 out of 10, Exceptional, (839)
"Clean, would stay again."
United States
Eryka
The price is S$160
includes taxes & fees
25 Dec - 26 Dec
Courtyard by Marriott St. Louis Brentwood
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
19.3 km from Uptown
8.6 out of 10, Excellent, (1011)
"The hotel itself was just beautiful and grand! Beautifully decorated for the holidays and the amenities and attractions surrounding Union station were perfect for our family of 4! Our room was spacious and clean and we loved our stay! "
United States
Kelly
The price is S$240
includes taxes & fees
4 Jan - 5 Jan, 2026
St. Louis Union Station Hotel, Curio Collection by Hilton
Hypo-allergenic bedding, free WiFi, bed sheets
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
18.4 km from Uptown
7.6 out of 10, Good, (596)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is S$122
includes taxes & fees
18 Jan - 19 Jan, 2026
Tru By Hilton St. Louis Downtown
Terrace/patio
The West End

The West End

The West End
2.0 star property
22.6 km from Uptown
8.4 out of 10, Very good, (407)
"Great stay!"
United States
Shaniqua
The price is S$130
includes taxes & fees
6 Jan - 7 Jan, 2026
The West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

Top Uptown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Good"
Daniel 1-night trip
Posted 2 days ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

What is Uptown like?
Travellers to the Uptown neighbourhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Make sure that you visit World's Largest Catsup Bottle and Kruta Bakery while you're in the neighbourhood.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer in Uptown.
What is there to do in this Collinsville neighbourhood?
A few attractions you might want to check out while you're in Uptown are World's Largest Catsup Bottle and Kruta Bakery. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.