Alaska Airlines flights to San Diego from Medford

Set the "Price (lowest to highest)" filter on Expedia to look for cheap Alaska Airlines round-trip flights from MFR to SAN. Affordable one-way tickets are also available.*

*These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to travel to San Diego with Alaska Airlines. You could also find great deals on return and one-way tickets in November.

Enter your dates, click search and select "Nonstop" on Expedia to find any direct flights from MFR to SAN with Alaska Airlines or another airline.

Board an Alaska Airlines flight from Rogue Valley Intl. Airport (MFR) to San Diego, and you'll likely land at San Diego Intl. Airport (SAN). This is the airline's primary hub here.

Depending on the type of ticket you purchased, a fee will generally apply if you modify or cancel your flight more than 24 hours after it has been confirmed. To find tickets with more flexibility, select our "Changes included" or "No cancel fee" filter when you look for flights. For more information on modifying or cancelling your reservation, visit "Trips," select your flight and tick "Manage Booking."