Popular airlines from Des Moines International Airport (DSM) to San Diego Intl. Airport (SAN)
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Alaska Airlines
Alaska Airlines
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 40% on select hotels after you book a flight*
Cheap Flights from Des Moines to San Diego (DSM-SAN)
Prices were available within the past 7 days and start at S$192 for one-way flights and S$383 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$383 Return, found 2 days ago
S$383
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$431 Return, found 2 days ago
S$431
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$442 Return, found 2 days ago
S$442
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$479 Return, found 2 days ago
S$479
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$483 Return, found 2 days ago
S$483
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$486 Return, found 2 days ago
S$486
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$486 Return, found 2 days ago
S$486
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$490 Return, found 2 days ago
S$490
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$493 Return, found 2 days ago
S$493
Return
found 2 days ago

Sat, 31 Jan - Sat, 7 Feb
DSM
Des Moines
SAN
San Diego
S$519 Return, found 2 days ago
S$519
Return
found 2 days ago
Find the cheapest month to fly from Des Moines (DSM) to San Diego (SAN)
April is typically the cheapest month to fly
From S$207 - S$656 per traveller.
Frequently asked questions
Travel information
Origin airport | Des Moines Intl. |
|---|---|
Destination airport | San Diego Intl. |
Return price | S$383 |
Distance | 2282 km |
Book with confidence
Perfect flights from Des Moines to San Diego
Your Journey from Des Moines to San Diego
Start your unforgettable journey with Expedia. Our broad selection of flights from Des Moines to San Diego caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
Choosing Your Ideal Flight
With Expedia, you have access to a wide range of airlines, including Delta, American Airlines, United. Our selection of flights from Des Moines Intl. to San Diego Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
Maximizing Value with Des Moines to San Diego Flights
Experience the joy of finding cheap flights from Des Moines Intl. to San Diego Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$192 and roundtrip prices from S$383*.
Pre-Flight Essentials
Ensure a smooth journey from Des Moines to San Diego with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
Experience the Vibrant San Diego
Picture yourself stepping off the plane in San Diego and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
Added Convenience on Your Des Moines to San Diego Flight
Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Des Moines to San Diego.
Beyond the Flight – Exploring San Diego
With Expedia, your adventure extends beyond the flight. Explore San Diego at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
Book Your Flight from Des Moines to San Diego with Confidence
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Des Moines to San Diego with confidence. Book your travel arrangements with Expedia today.
*Note: Prices may vary based on availability and are subject to change.
Explore a world of travel with Expedia
- Adults Only Hotels in Coronado Island
- Hotels with Bars / Lounges in Coronado Island
- Liberty Station Hotels
- Budget Hotels in Little Italy
- Little Italy Hotels
- Hotels near Old Town San Diego State Park
- Cabin Rentals in San Diego
- Caravan Parks in San Diego
- Ranches in San Diego County
- Guest Houses in San Diego
- Private Holiday Homes in San Diego
- Hotels with Airport Shuttle in San Diego
- Hotels near San Diego Intl.
- Flights from San Diego Intl.
- Air Canada Nice (NCE) to San Diego (SAN) flights
- Alaska Airlines Ontario (ONT) to San Diego (SAN) flights
- Alaska Airlines Washington (DCA) to San Diego (SAN) flights
- Alaska Airlines San Francisco (SFO) to San Diego (SAN) flights
- Alaska Airlines Santa Rosa (STS) to San Diego (SAN) flights
- American Airlines Bozeman (BZN) to San Diego (SAN) flights
- American Airlines Chicago (CHI) to San Diego (SAN) flights
- American Airlines Miami (MIA) to San Diego (SAN) flights
- British Airways Singapore (SIN) to San Diego (SAN) flights
- British Airways Geneva (GVA) to San Diego (SAN) flights
- British Airways Copenhagen (CPH) to San Diego (SAN) flights
- Delta Austin (AUS) to San Diego (SAN) flights
- Delta Charleston (CHS) to San Diego (SAN) flights
- Delta Grand Rapids (GRR) to San Diego (SAN) flights
- Delta São Paulo (GRU) to San Diego (SAN) flights
- Delta Atlanta (ATL) to San Diego (SAN) flights
- Delta Cleveland (CLE) to San Diego (SAN) flights
- Delta London (LON) to San Diego (SAN) flights
- Delta Chicago (MDW) to San Diego (SAN) flights
- Delta West Palm Beach (PBI) to San Diego (SAN) flights
- Delta Pensacola (PNS) to San Diego (SAN) flights
- Delta San Antonio (SAT) to San Diego (SAN) flights
- Delta Amsterdam (AMS) to San Diego (SAN) flights
- Delta Fort Myers (RSW) to San Diego (SAN) flights
- Delta Anchorage (ANC) to San Diego (SAN) flights
- Delta Wichita (ICT) to San Diego (SAN) flights
- Emirates Singapore (SIN) to San Diego (SAN) flights
- Japan Airlines Seoul (GMP) to San Diego (SAN) flights
- Klm Singapore (SIN) to San Diego (SAN) flights
- Klm Munich (MUC) to San Diego (SAN) flights
- Klm Delhi (DEL) to San Diego (SAN) flights
- Klm Paris (CDG) to San Diego (SAN) flights
- Klm Amsterdam (AMS) to San Diego (SAN) flights
- Lufthansa Singapore (SIN) to San Diego (SAN) flights
- Lufthansa Dubai (DXB) to San Diego (SAN) flights
- Lufthansa Munich (MUC) to San Diego (SAN) flights
- Lufthansa London (LHR) to San Diego (SAN) flights
- Malaysia Airlines Medan (MES) to San Diego (SAN) flights
- Qatar Airways Chennai (MAA) to San Diego (SAN) flights
- United Frankfurt (FRA) to San Diego (SAN) flights
- United Zürich (ZRH) to San Diego (SAN) flights
- Flights from Allentown (ABE) to San Diego (SAN)
- Flights from Eureka (ACV) to San Diego (SAN)
- Flights from Abu Dhabi (AZI) to San Diego (SAN)
- Flights from Casablanca (CMN) to San Diego (SAN)
- Flights from Hancock (CMX) to San Diego (SAN)
- Flights from Delhi (DEL) to San Diego (SAN)
- Flights from Guadalajara (GDL) to San Diego (SAN)
- Flights from Guatemala City (GUA) to San Diego (SAN)
- Flights from Huntsville (HSV) to San Diego (SAN)
- Flights from Seoul (ICN) to San Diego (SAN)
- Flights from Istanbul (IST) to San Diego (SAN)
- Flights from Osaka (KIX) to San Diego (SAN)
- Flights from Laramie (LAR) to San Diego (SAN)
- Flights from Lancaster (LNS) to San Diego (SAN)
- Flights from Liverpool (LPL) to San Diego (SAN)
- Flights from Kayenta (MVM) to San Diego (SAN)
- Flights from Jacksonville (OAJ) to San Diego (SAN)
- Flights from Omaha (OMA) to San Diego (SAN)
- Flights from Port of Spain (POS) to San Diego (SAN)
- Flights from Riverside (RAL) to San Diego (SAN)
- Flights from Raleigh (RDU) to San Diego (SAN)
- Flights from Sibiu (SBZ) to San Diego (SAN)
- Flights from Singapore (SIN) to San Diego (SAN)
- Flights from San José del Cabo (SJD) to San Diego (SAN)
- Flights from Santa Rosa (STS) to San Diego (SAN)
- Flights from Toulouse (TLS) to San Diego (SAN)
- Flights from Torrance (TOA) to San Diego (SAN)
- Flights from Tarawa (TRW) to San Diego (SAN)
- Flights from Vieux Fort (UVF) to San Diego (SAN)
- Flights from Valencia (VLC) to San Diego (SAN)
- Alamo Rent A Car Rental Cars in San Diego Intl.
- Avis Rental Cars in San Diego Intl.
- Budget Rental Cars in San Diego Intl.
- Rental cars San Diego Intl. airport
- Car hire near USS Midway Museum
- Car hire near San Diego County
- Dollar Rent A Car Rental Cars in San Diego Intl.
- Enterprise Rental Cars in San Diego Intl.
- Firefly Rental Cars in San Diego Intl.
- Fox Rental Cars Rental Cars in San Diego Intl.
- Luxury Car Hire near San Diego Intl.
- National Car Rental Rental Cars in San Diego Intl.
- Rent A Wreck Rental Cars in San Diego Intl.
*Available to Expedia members.
