S$403 Cheap Flights from Mexico City to Santiago

View S$403 flight on Wed, 12 Nov, 2025Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Santiago Intl. Airport (SCL)

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Cheap Flights from Mexico City to Santiago (MEX-SCL)

Prices were available within the past 7 days and start at S$403 for one-way flights and S$878 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$878 Return, found 1 day ago
S$878
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$878 found 1 day ago
Aeromexico
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$934 Return, found 1 day ago
S$934
Return
found 1 day ago
Select Aeromexico flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$934 found 1 day ago
avianca
Mon, 4 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
S$936 Return, found 3 days ago
S$936
Return
found 3 days ago
Select avianca flight, departing Mon, 4 May from Mexico City to Santiago, returning Thu, 7 May, priced at S$936 found 3 days ago
avianca
Mon, 4 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
S$940 Return, found 3 days ago
S$940
Return
found 3 days ago
Select avianca flight, departing Mon, 4 May from Mexico City to Santiago, returning Thu, 7 May, priced at S$940 found 3 days ago
LATAM Airlines Group
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$952 Return, found 1 day ago
S$952
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$952 found 1 day ago
LATAM Airlines Group
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$982 Return, found 1 day ago
S$982
Return
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$982 found 1 day ago
avianca
Mon, 4 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
S$1,004 Return, found 3 days ago
S$1,004
Return
found 3 days ago
Select avianca flight, departing Mon, 4 May from Mexico City to Santiago, returning Thu, 7 May, priced at S$1,004 found 3 days ago
Aeromexico
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$1,019 Return, found 1 day ago
S$1,019
Return
found 1 day ago
Select Aeromexico flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$1,019 found 1 day ago
Copa
Mon, 4 May - Thu, 7 May
MEX
Mexico City
SCL
Santiago
S$1,121 Return, found 3 days ago
S$1,121
Return
found 3 days ago
Select Copa flight, departing Mon, 4 May from Mexico City to Santiago, returning Thu, 7 May, priced at S$1,121 found 3 days ago
United
Sun, 14 Dec - Sun, 21 Dec
MEX
Mexico City
SCL
Santiago
S$1,816 Return, found 1 day ago
S$1,816
Return
found 1 day ago
Select United flight, departing Sun, 14 Dec from Mexico City to Santiago, returning Sun, 21 Dec, priced at S$1,816 found 1 day ago

Find the cheapest month to fly from Mexico City (MEX) to Santiago (SCL)

May is typically the cheapest month to fly

From S$494 - S$913 per traveller.
Mexico City to Santiago route information
Origin airport
Mexico City Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aeromexico, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca
Return price
S$878
Distance
6558 km
Average flight time
11 hours 27 mins

Perfect flights from Mexico City to Santiago

Your Journey from Mexico City to Santiago

Start your unforgettable journey with Expedia. Our broad selection of flights from Mexico City to Santiago caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including avianca, Copa, LATAM Airlines Group, Aeromexico, United. Our selection of flights from Mexico City Intl. to Arturo Merino Benitez caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with Mexico City to Santiago Flights

Experience the joy of finding cheap flights from Mexico City Intl. to Arturo Merino Benitez that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$403 and roundtrip prices from S$878*.
 

Pre-Flight Essentials

Ensure a smooth journey from Mexico City to Santiago with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Santiago

Picture yourself stepping off the plane in Santiago and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your Mexico City to Santiago Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Mexico City to Santiago.
 

Beyond the Flight – Exploring Santiago

With Expedia, your adventure extends beyond the flight. Explore Santiago at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from Mexico City to Santiago with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Mexico City to Santiago with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from Benito Juárez Intl. Airport to Santiago International Airport?
The lowest price advertised for a round-trip journey from Mexico City Intl. Airport (MEX) to Santiago International Airport is S$878. But you better act quick. This figure is based on fares listed within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Mexico City Intl. Airport (MEX) to SCL?
When it comes to cancellation fees, each airline has a different set of terms and conditions. If you decide to cancel your escape, head to our Customer Service Portal.
How do I find cheap flights from MEX to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Mexico City Intl. Airport (MEX) to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from MEX to Nuevo Pudahuel Airport?
With a flight distance of 6,600 kilometres from Mexico Airport (MEX) to Arturo Merino Benitez Airport (SCL) (SCL), this is a long journey. Ensure that you stay hydrated and move around the cabin every so often.
Which airlines fly direct from Benito Juárez Intl. Airport to Nuevo Pudahuel Airport?
Many travellers opt to fly with LATAM Airlines (LA) from Mexico Airport to SCL. It offers 30 flights every month, so you can easily find a flight time that works for you. Offering 21 flights every month along this route, Aeromexico (AM) is another traveller favourite.
Are Mexico Airport to Nuevo Pudahuel Airport flight tickets cheaper when they're purchased at the last minute?
Booking last minute from MEX to Arturo Merino Benitez Airport (SCL) can be hit-or-miss. You may be able to find a bargain, but then again, you could miss out entirely! If you'd prefer to play it safe and start your trip planning early, Expedia compares flight deals up to 12 months in advance. Just bear in mind that not all airlines release their prices so far in advance. Our top tip? Check back often as prices are updated regularly.

Explore a world of travel with Expedia

*Available to Expedia members.