S$270 Cheap Flights from Panama City to Mexico City

View S$270 flight on Thu, 16 Oct, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Benito Juarez International Airport (MEX)

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Cheap Flights from Panama City to Mexico City (PTY-MEX)

Prices were available within the past 7 days and start at S$270 for one-way flights and S$470 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$470 Return, found 2 days ago
S$470
Return
found 2 days ago
Select Aeromexico flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$470 found 2 days ago
Copa
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$535 Return, found 2 days ago
S$535
Return
found 2 days ago
Select Copa flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$535 found 2 days ago
avianca
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$710 Return, found 2 days ago
S$710
Return
found 2 days ago
Select avianca flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$710 found 2 days ago
avianca
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$748 Return, found 2 days ago
S$748
Return
found 2 days ago
Select avianca flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$748 found 2 days ago
avianca
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$807 Return, found 2 days ago
S$807
Return
found 2 days ago
Select avianca flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$807 found 2 days ago
Copa
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$824 Return, found 2 days ago
S$824
Return
found 2 days ago
Select Copa flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$824 found 2 days ago
Copa
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$865 Return, found 2 days ago
S$865
Return
found 2 days ago
Select Copa flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$865 found 2 days ago
Copa
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$892 Return, found 2 days ago
S$892
Return
found 2 days ago
Select Copa flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$892 found 2 days ago
American Airlines
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$989 Return, found 2 days ago
S$989
Return
found 2 days ago
Select American Airlines flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$989 found 2 days ago
United
Wed, 17 Sep - Sat, 20 Sep
PTY
Panama City
MEX
Mexico City
S$1,923 Return, found 2 days ago
S$1,923
Return
found 2 days ago
Select United flight, departing Wed, 17 Sep from Panama City to Mexico City, returning Sat, 20 Sep, priced at S$1,923 found 2 days ago

Find the cheapest month to fly from Panama City (PTY) to Mexico City (MEX)

July is typically the cheapest month to fly

From S$309 - S$562 per traveller.

Graph displaying average flight prices per month

Panama City to Mexico City route information
Origin airport
Tocumen Intl.
Destination airport
Mexico City Intl.
Return price
S$470
Distance
2397 km
Average flight time
2 hours 46 mins

Flights from Tocumen to Mexico City

There are several airlines that operate frequent flights from Panama (PTY) to Mexico City (MEX) including

  • COPA Airlines with 116 flights a week
  • Aeromexico with 63 flights a week
  • AVIANCA with 15 flights a week

The earliest flight leaves Tocumen Intl. Airport at 07:32 and arrives at Mexico City Intl. Airport at 00:17. The last flight of the day departs Panama at 21:23 and arrives at Mexico City at 23:08.

The flight distance from Panama to Mexico City is about 2423 km, the shortest flight is 03 hours 54 minutes with COPA Airlines.

Expedia lets you search across the largest number of airlines and Mexico City flights, which means that you’ll be able to find a great flight deal at the perfect travel date and time. Our simple-to-use booking engine makes looking for terrific bargains easy and hassle-free; just enter your travel dates and departure city, and let Expedia do the rest! Adjust your travel dates and explore connecting flights to find an even better deal on your Tocumen Mexico City flight!

Browse through dozens of options and rest assured that you’re seeing the best price guaranteed! Our friendly customer service representatives are here to serve you 24 hours day to provide assistance and answer any questions that you may have about booking your Tocumen to Mexico City trip. There’s simply no substitute for great prices suited to your travel needs and backed by excellent customer support.

Combine your Mexico City flight with a hotel and/or car rental for a package deal designed to save you even more money! Discover additional savings by booking in advance or find a last minute deal. There are tons of ways to save on your flights from Tocumen to Mexico City with Expedia. Use us as your stop travel destination and have the confidence that you’re getting a bargain!

Frequently asked questions

How much is a flight from Panama Airport to MEX?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price available for a round-trip journey between Panama Airport and Benito Juárez Intl. Airport was S$470. Great fares don't last forever, so make sure you book yours ASAP. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to MEX?
When it comes to cancellation fees, each airline has its own terms and conditions. If you decide to cancel your trip, head to our Customer Service Portal.
How do I find cheap flights from Tocumen Intl. Airport (PTY) to Mexico Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to Benito Juárez Intl. Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Tocumen Intl. Airport (PTY) to Mexico Airport?
Around 2,400 kilometres separates Tocumen and Mexico City, so pack some entertainment to keep you occupied for a few hours. That gripping novel you've yet to start will be perfect.
Which airlines fly direct from Panama Airport to Mexico City Intl. Airport (MEX)?
Operating 147 flights monthly, Copa Airlines (CM) is a top choice when flying straight from PTY to Mexico Airport.
Are Panama Airport to Mexico Airport flight tickets cheaper when they're purchased at the last minute?
Tickets from Tocumen Intl. Airport (PTY) to MEX are available up to a year prior to departure on Expedia. And although you may nab a fantastic last-minute deal, it's never a sure thing. Also, booking your flights well in advance means you'll have more options — and you can avoid getting caught in the dreaded middle seat! We regularly update our fares to bring you the biggest bargains, so check back often for all the latest specials.

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