Cheap Flights from Roanoke to Chicago

Start packing your suitcase, because round-trip journeys from Roanoke Regional Airport (ROA) to ORD start from . That's based on fares listed within the last 7 days on Expedia for flights departing within the next year. Prices can increase quickly, so book now to lock in the best deal. Prices and availability are subject to change. Additional terms apply.

Each air carrier has its own terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.

Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Roanoke Regional Airport (ROA) to O'Hare Airport flights, you'll see a "no change fees" filter for you to select.

Forget about a movie marathon on this flight — it's only 850 kilometres from Roanoke to Chicago. Sit down, buckle up and you'll be there before long.

Flying nonstop from Roanoke–Blacksburg Regional Airport to O'Hare Intl. Airport (ORD) is a cinch with United Airlines (UA). This top carrier offers 91 flights every month.

Fares from ROA to ORD are available up to a year before departure on Expedia. And although you may score a fantastic last-minute deal, it's not something you should bank on. Also, booking your flights in advance means you'll have more choices — and you can avoid getting caught in the dreaded middle seat! We're constantly updating our fares to bring you the biggest bargains, so keep checking in for all the latest specials.