S$366 Cheap Flights from Santiago to Panama City

View S$366 flight on Fri, 24 Oct, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Tocumen Intl. Airport (PTY)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 40% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Santiago to Panama City (SCL-PTY)

Prices were available within the past 7 days and start at S$366 for one-way flights and S$660 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, 24 Oct - Tue, 28 Oct
SCL
Santiago
PTY
Panama City
S$660 Return, found 1 day ago
S$660
Return
found 1 day ago
Select Copa flight, departing Fri, 24 Oct from Santiago to Panama City, returning Tue, 28 Oct, priced at S$660 found 1 day ago
avianca
Fri, 24 Oct - Tue, 28 Oct
SCL
Santiago
PTY
Panama City
S$766 Return, found 1 day ago
S$766
Return
found 1 day ago
Select avianca flight, departing Fri, 24 Oct from Santiago to Panama City, returning Tue, 28 Oct, priced at S$766 found 1 day ago
Copa
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$776 Return, found 1 day ago
S$776
Return
found 1 day ago
Select Copa flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$776 found 1 day ago
Copa
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$795 Return, found 1 day ago
S$795
Return
found 1 day ago
Select Copa flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$795 found 1 day ago
Copa
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$802 Return, found 1 day ago
S$802
Return
found 1 day ago
Select Copa flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$802 found 1 day ago
Copa
Fri, 24 Oct - Tue, 28 Oct
SCL
Santiago
PTY
Panama City
S$839 Return, found 1 day ago
S$839
Return
found 1 day ago
Select Copa flight, departing Fri, 24 Oct from Santiago to Panama City, returning Tue, 28 Oct, priced at S$839 found 1 day ago
avianca
Fri, 24 Oct - Tue, 28 Oct
SCL
Santiago
PTY
Panama City
S$856 Return, found 1 day ago
S$856
Return
found 1 day ago
Select avianca flight, departing Fri, 24 Oct from Santiago to Panama City, returning Tue, 28 Oct, priced at S$856 found 1 day ago
Copa
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$897 Return, found 1 day ago
S$897
Return
found 1 day ago
Select Copa flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$897 found 1 day ago
Aeromexico
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$1,438 Return, found 1 day ago
S$1,438
Return
found 1 day ago
Select Aeromexico flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$1,438 found 1 day ago
American Airlines
Tue, 6 Jan - Tue, 13 Jan
SCL
Santiago
PTY
Panama City
S$2,119 Return, found 1 day ago
S$2,119
Return
found 1 day ago
Select American Airlines flight, departing Tue, 6 Jan from Santiago to Panama City, returning Tue, 13 Jan, priced at S$2,119 found 1 day ago

Find the cheapest month to fly from Santiago (SCL) to Panama City (PTY)

November is typically the cheapest month to fly

From S$525 - S$928 per traveller.
Santiago to Panama City route information
Origin airport
Arturo Merino Benitez
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Copa, avianca
Return price
S$660
Distance
4780 km
Average flight time
4 hours 51 mins

Perfect flights from Santiago to Panama City

Your Journey from Santiago to Panama City

Start your unforgettable journey with Expedia. Our broad selection of flights from Santiago to Panama City caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including avianca, Copa, Aeromexico, Delta, United, American Airlines. Our selection of flights from Arturo Merino Benitez to Tocumen Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with Santiago to Panama City Flights

Experience the joy of finding cheap flights from Arturo Merino Benitez to Tocumen Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$366 and roundtrip prices from S$660*.
 

Pre-Flight Essentials

Ensure a smooth journey from Santiago to Panama City with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Panama City

Picture yourself stepping off the plane in Panama City and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your Santiago to Panama City Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Santiago to Panama City.
 

Beyond the Flight – Exploring Panama City

With Expedia, your adventure extends beyond the flight. Explore Panama City at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from Santiago to Panama City with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Santiago to Panama City with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from Santiago International Airport to Tocumen Intl. Airport (PTY)?
Start packing your bags, because round-trip journeys from Santiago International Airport to Panama Airport start from S$660. That's based on fares advertised within the last 7 days on Expedia for flights departing within the next year. Prices can rise quickly, so book now to get the best deal. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from SCL to Panama Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the instructions on our Customer Service Portal.
How do I find cheap flights from Nuevo Pudahuel Airport to Tocumen Intl. Airport (PTY) that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SCL to PTY flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Santiago International Airport to PTY?
The distance is around 4,800 kilometres. Earplugs? Check. Toothbrush? Check. You'll need to pack all the essentials for this long-haul Santiago to Tocumen flight.
Which airlines fly direct from Santiago International Airport to Panama Airport?
Flying directly from Nuevo Pudahuel Airport to Panama Airport is a cinch with Copa Airlines (CM). This top airline offers 169 flights each month.
Are SCL to Panama Airport flight tickets cheaper when they're purchased at the last minute?
Last-minute bookings from Santiago International Airport to PTY can be hit-or-miss. You may be able to find a bargain, but you could also miss out completely! If you'd prefer to start planning ahead of time, Expedia compares flight deals up to 12 months in advance. Just keep in mind that not all airlines release their prices that far in advance. Our advice? Check back often as prices are updated frequently.

Explore a world of travel with Expedia

*Available to Expedia members.