Photo by PhotoJoy

Popular airlines to Panama
Avianca
American Airlines
United
Delta
Copa
Aeromexico
KLM
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 40% on select hotels after you book a flight*
Cheap round-trip flights to Panama
Prices were available within the past 7 days and start at S$257 for one-way flights and S$757 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$757 Return, found 1 day ago
S$757
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$764 Return, found 1 day ago
S$764
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$771 Return, found 1 day ago
S$771
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$771 Return, found 1 day ago
S$771
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$778 Return, found 1 day ago
S$778
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$780 Return, found 1 day ago
S$780
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$785 Return, found 1 day ago
S$785
Return
found 1 day ago

Mon, 16 Feb - Mon, 23 Feb
DSM
Des Moines
PTY
Panama City
S$854 Return, found 1 day ago
S$854
Return
found 1 day ago

Fri, 13 Mar - Wed, 18 Mar
SIN
Singapore
PTY
Panama City
S$1,633 Return, found 2 days ago
S$1,633
Return
found 2 days ago

Thu, 26 Mar - Fri, 3 Apr
SIN
Singapore
PTY
Panama City
S$1,799 Return, found 1 day ago
S$1,799
Return
found 1 day ago
Trending flights to Panama
These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 13 Mar - Wed, 18 Mar
SIN
Singapore
PTY
Panama City
S$1,633 Return, found 2 days ago
S$1,633
Return
found 2 days ago
Frequently asked questions
Book with confidence
Expedia offers flights to Panama to meet every traveller's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to Panama or destinations around the world and discover how easy it is to make your flight reservations on Expedia.
Travel information
Panama Flights Information
Airlines serving | Delta, United, American Airlines, EVA Airways, Singapore Airlines |
|---|---|
Roundtrip price | from S$757 |
Explore a world of travel with Expedia
Top Flight Destinations In the World
- Flights to China
- Flights to Brazil
- Flights to United States of America
- Flights to United Kingdom
- Flights to France
- Flights to Philippines
- Flights to Russia
- Flights to South Korea
- Flights to India
- Flights to Switzerland
- Flights to Japan
- Flights to Spain
- Flights to Greece
- Flights to Argentina
- Flights to Türkiye
- Flights to Colombia
- Flights to Italy
- Flights to Germany
- Flights to Indonesia
- Flights to Canada
Top Panama Hotels
- Hotel Riu Plaza Panama
- Crowne Plaza Panama Airport by IHG
- Megapolis Hotel Panamá
- Las Americas Golden Tower Panama
- Waldorf Astoria Panama
- Marriott Panama Hotel
- Plaza Paitilla Inn Hotel
- Grand Decameron Panama, A Trademark All Inclusive Resort
- The Westin Playa Bonita Panama
- JW Marriott Panama
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Dreams Playa Bonita Panama - All Inclusive
- Hyatt Regency Panama City
- Sheraton Grand Panama
- Decapolis Hotel Panama City
- AC Hotel by Marriott Panama City
- The Executive Hotel
- W Panama
Expedia's Latest Trends
Hotels
- Ramada Encore by Wyndham Haeundae
- The Robertson Kuala Lumpur
- Highland Resort Hotel & Spa
- 4 Star Hotels in Kuta
- Pullman Singapore Orchard
- G Hotel Gurney
- Puerto Princesa Beach Resorts
- BESPOKE HOTEL Shinjuku
- Hotels with smoking rooms in El Salvador
- Tha Phae Gate hotels
- Hotels with Early Check In in Costa Rica
- HiltonHotels Hotels in Chiang Mai
Flights
Activities
*Available to Expedia members.
