S$204 Cheap Flights from San Francisco to Des Moines

View S$204 flight on Wed, 1 Oct, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Des Moines International Airport (DSM)

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Cheap Flights from San Francisco to Des Moines (SFO-DSM)

Prices were available within the past 7 days and start at S$204 for one-way flights and S$522 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$522 Return, found 1 day ago
S$522
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$522 found 1 day ago
Delta
Sun, 16 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$536 Return, found 1 day ago
S$536
Return
found 1 day ago
Select Delta flight, departing Sun, 16 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$536 found 1 day ago
Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$548 Return, found 1 day ago
S$548
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$548 found 1 day ago
Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$554 Return, found 1 day ago
S$554
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$554 found 1 day ago
Delta
Sun, 16 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$561 Return, found 1 day ago
S$561
Return
found 1 day ago
Select Delta flight, departing Sun, 16 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$561 found 1 day ago
Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$576 Return, found 1 day ago
S$576
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$576 found 1 day ago
United
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$581 Return, found 1 day ago
S$581
Return
found 1 day ago
Select United flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$581 found 1 day ago
Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$582 Return, found 1 day ago
S$582
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$582 found 1 day ago
Delta
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$586 Return, found 1 day ago
S$586
Return
found 1 day ago
Select Delta flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$586 found 1 day ago
American Airlines
Mon, 17 Nov - Fri, 21 Nov
SFO
San Francisco
DSM
Des Moines
S$606 Return, found 1 day ago
S$606
Return
found 1 day ago
Select American Airlines flight, departing Mon, 17 Nov from San Francisco to Des Moines, returning Fri, 21 Nov, priced at S$606 found 1 day ago

Find the cheapest month to fly from San Francisco (SFO) to Des Moines (DSM)

October is typically the cheapest month to fly

From S$152 - S$596 per traveller.

Graph displaying average flight prices per month

San Francisco to Des Moines route information
Origin airport
San Francisco Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, United
Return price
S$522
Distance
2474 km

Perfect flights from San Francisco to Des Moines

Your Journey from San Francisco to Des Moines

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Des Moines caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including Delta, American Airlines, United. Our selection of flights from San Francisco Intl. to Des Moines Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Des Moines Flights

Experience the joy of finding cheap flights from San Francisco Intl. to Des Moines Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$204 and roundtrip prices from S$522*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Des Moines with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Des Moines

Picture yourself stepping off the plane in Des Moines and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Des Moines Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Des Moines.
 

Beyond the Flight – Exploring Des Moines

With Expedia, your adventure extends beyond the flight. Explore Des Moines at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Des Moines with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Des Moines with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from SFO to DSM?
The lowest price advertised for a round-trip flight from San Francisco Airport to Des Moines Intl. Airport is S$522. But you better get a move on. This price is taken from fares available within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Airport to Des Moines Intl. Airport (DSM)?
The majority of flights can be cancelled online, but whether or not you incur a fee depends on your airline. If you do have to cancel your trip, follow the easy instructions in the Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Des Moines Intl. Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SFO to DSM flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to DSM?
You'll be in the air for a while, as the flight distance between San Francisco and Des Moines is 2,500 kilometres. Create a playlist of your favourite podcasts before leaving home to stay entertained during your flight.
Which airlines fly direct from San Francisco Airport to Des Moines Intl. Airport?
Flying directly between San Francisco Airport and Des Moines Intl. Airport isn't possible at the moment. However, you'll still be able to book a flight to Des Moines with at least one stop.
Are SFO to Des Moines Intl. Airport (DSM) flight tickets cheaper when they're purchased at the last minute?
Booking last minute from SFO to Des Moines Intl. Airport (DSM) can be hit-or-miss. You may be able to find a bargain, but you could also miss out entirely! If you'd rather start your travel planning early, Expedia compares flight deals up to a year in advance. Just bear in mind that not all airlines publish their prices so far in advance. Our advice? Check back often as updates are made frequently.

Explore a world of travel with Expedia

*Available to Expedia members.