S$438 Cheap Flights from San Francisco to Knoxville

View S$438 flight on Mon, 22 Dec, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to McGhee Tyson Airport (TYS)

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Cheap Flights from San Francisco to Knoxville (SFO-TYS)

Prices were available within the past 7 days and start at S$438 for one-way flights and S$573 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, 25 Dec - Thu, 8 Jan
SFO
San Francisco
TYS
Knoxville
S$573 Return, found 18 hours ago
S$573
Return
found 18 hours ago
Select Delta flight, departing Thu, 25 Dec from San Francisco to Knoxville, returning Thu, 8 Jan, priced at S$573 found 18 hours ago
United
Wed, 24 Dec - Mon, 5 Jan
SFO
San Francisco
TYS
Knoxville
S$658 Return, found 18 hours ago
S$658
Return
found 18 hours ago
Select United flight, departing Wed, 24 Dec from San Francisco to Knoxville, returning Mon, 5 Jan, priced at S$658 found 18 hours ago
Delta
Tue, 23 Dec - Thu, 8 Jan
SFO
San Francisco
TYS
Knoxville
S$697 Return, found 18 hours ago
S$697
Return
found 18 hours ago
Select Delta flight, departing Tue, 23 Dec from San Francisco to Knoxville, returning Thu, 8 Jan, priced at S$697 found 18 hours ago
United
Thu, 25 Dec - Mon, 5 Jan
SFO
San Francisco
TYS
Knoxville
S$723 Return, found 18 hours ago
S$723
Return
found 18 hours ago
Select United flight, departing Thu, 25 Dec from San Francisco to Knoxville, returning Mon, 5 Jan, priced at S$723 found 18 hours ago
American Airlines
Fri, 19 Dec - Thu, 8 Jan
SFO
San Francisco
TYS
Knoxville
S$782 Return, found 18 hours ago
S$782
Return
found 18 hours ago
Select American Airlines flight, departing Fri, 19 Dec from San Francisco to Knoxville, returning Thu, 8 Jan, priced at S$782 found 18 hours ago
American Airlines
Mon, 22 Dec - Mon, 5 Jan
SFO
San Francisco
TYS
Knoxville
S$786 Return, found 18 hours ago
S$786
Return
found 18 hours ago
Select American Airlines flight, departing Mon, 22 Dec from San Francisco to Knoxville, returning Mon, 5 Jan, priced at S$786 found 18 hours ago
Delta
Thu, 25 Dec - Sun, 4 Jan
SFO
San Francisco
TYS
Knoxville
S$793 Return, found 18 hours ago
S$793
Return
found 18 hours ago
Select Delta flight, departing Thu, 25 Dec from San Francisco to Knoxville, returning Sun, 4 Jan, priced at S$793 found 18 hours ago
American Airlines
Sun, 21 Dec - Thu, 8 Jan
SFO
San Francisco
TYS
Knoxville
S$808 Return, found 18 hours ago
S$808
Return
found 18 hours ago
Select American Airlines flight, departing Sun, 21 Dec from San Francisco to Knoxville, returning Thu, 8 Jan, priced at S$808 found 18 hours ago
United
Tue, 23 Dec - Mon, 5 Jan
SFO
San Francisco
TYS
Knoxville
S$825 Return, found 18 hours ago
S$825
Return
found 18 hours ago
Select United flight, departing Tue, 23 Dec from San Francisco to Knoxville, returning Mon, 5 Jan, priced at S$825 found 18 hours ago
American Airlines
Sat, 20 Dec - Thu, 8 Jan
SFO
San Francisco
TYS
Knoxville
S$832 Return, found 18 hours ago
S$832
Return
found 18 hours ago
Select American Airlines flight, departing Sat, 20 Dec from San Francisco to Knoxville, returning Thu, 8 Jan, priced at S$832 found 18 hours ago

Find the cheapest month to fly from San Francisco (SFO) to Knoxville (TYS)

January is typically the cheapest month to fly

From S$204 - S$694 per traveller.
San Francisco to Knoxville route information
Origin airport
San Francisco Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Return price
S$573
Distance
3385 km
Average flight time
7 hours 6 mins

Perfect flights from San Francisco to Knoxville

Your Journey from San Francisco to Knoxville

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Knoxville caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including American Airlines, Delta, United, Alaska Airlines. Our selection of flights from San Francisco Intl. to McGhee Tyson caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Knoxville Flights

Experience the joy of finding cheap flights from San Francisco Intl. to McGhee Tyson that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$438 and roundtrip prices from S$573*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Knoxville with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Knoxville

Picture yourself stepping off the plane in Knoxville and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Knoxville Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Knoxville.
 

Beyond the Flight – Exploring Knoxville

With Expedia, your adventure extends beyond the flight. Explore Knoxville at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Knoxville with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Knoxville with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from SFO to McGhee Tyson Airport (TYS)?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip journey from San Francisco Airport to McGhee Tyson Airport (TYS) was S$573. Fares this good don't wait forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Knoxville Airport?
Most flights can be cancelled online, but whether or not you incur a fee differs between airlines. If you do need to cancel your trip, follow the instructions in the Customer Service Portal.
How do I find cheap flights from SFO to Knoxville Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SFO to TYS flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to McGhee Tyson Airport (TYS)?
The flight distance from San Francisco to Alcoa is 3,400 kilometres. Bring a drink, a few snacks and a laptop filled with movies. Keep yourself entertained and the time will fly by.
Which airlines fly direct from San Francisco Intl. Airport (SFO) to Knoxville Airport?
You won't find any airlines flying directly between San Francisco Airport and TYS, so be prepared to make at least one stop on your journey. A layover can be a good way to break up a trip!
Are San Francisco Intl. Airport (SFO) to TYS flight tickets cheaper when they're purchased at the last minute?
Booking your trip from San Francisco Intl. Airport (SFO) to Knoxville Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the biggest bargains as far ahead as 12 months in advance. If your preferred carrier hasn't released tickets yet, check back regularly as deals are updated on Expedia all the time.

Explore a world of travel with Expedia

*Available to Expedia members.