What is Barrio de Santiago like?

Travellers to Mérida's Barrio de Santiago neighbourhood will be sure to enjoy a stay here. Make sure that you visit Casa Frederick Catherwood and Catherwood House Museum as part of your Barrio de Santiago travel plans.

What's a favourite hotel to stay in Barrio de Santiago?

Based on our traveller data, Hotel Unknown is one of the top choices for your stay in Barrio de Santiago. This hotel offers a full-service spa and free breakfast. Other good choices for your stay in the neighbourhood include Hotel Casa 57 and Casa Loreto 1893 .

How many hotels can I expect to find in the Barrio de Santiago area?

Expedia has 134 hotels and other accommodation options in Barrio de Santiago to choose from, making this an ideal home base for exploring the greater Mérida area.

If I need to cancel my hotel reservation in Barrio de Santiago, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get top deals in Barrio de Santiago.

What are the top things to see and do in Barrio de Santiago?

Casa Frederick Catherwood, Catherwood House Museum and Merida English Library are just a few attractions to check out in Barrio de Santiago. Parque Zoológico del Centenario and Zoological Park of Centenario are also worth a visit when you're out sightseeing in Mérida.

Top 10 Barrio de Santiago Hotels of 2026

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Our top choices for Barrio de Santiago hotels

A stone-walled spa area with a hot tub, towels, and a bottle of wine.

1. Casa Aura Hotel, Mérida

Barrio de Santiago

Isidro

includes taxes & fees

27 Oct - 28 Oct

A modern apartment with a wooden door, a balcony with a railing, and a potted plant.

2. Hotel Casa 57

Barrio de Santiago

Juan

includes taxes & fees

6 Oct - 7 Oct

A modern hotel with a pool, outdoor seating, and a well-lit balcony area.

3. Casona 61 Boutique Hotel

Barrio de Santiago

Maria

includes taxes & fees

21 Oct - 22 Oct

A hotel room with a large bed, a wooden headboard, a nightstand with a lamp, a chair, and a view of a garden through the window.

4. Hotel Unknown

Barrio de Santiago

Pascual Reyes

includes taxes & fees

5 Nov - 6 Nov

A spa area with a heated stone bath, wooden flooring, and a glass door leading to a hallway.

5. Casa Tunkul

Barrio de Santiago

Jose luis

includes taxes & fees

7 Oct - 8 Oct

A courtyard with benches, lush greenery, and a building with large windows.

6. Hotel Ambassador Merida

Barrio de Santiago

Arturo de Jesus

includes taxes & fees

6 Oct - 7 Oct

A nighttime pool area with a circular pool, palm trees, and ambient lighting.

7. Hotel Zamna

Barrio de Santiago

Jacqueline

includes taxes & fees

5 Nov - 6 Nov

A courtyard with a red building featuring arched windows and a covered seating area.

8. Casa Loreto 1893

Barrio de Santiago

Maria Elena

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with a brick wall, a waterfall feature, and a wicker basket with towels.

9. Viva Merida Hotel Boutique

Barrio de Santiago

Anonymous traveller

includes taxes & fees

21 Oct - 22 Oct

A pool area with a clear view of the water, lounge chairs, and palm trees.

10. The Diplomat Boutique Hotel

Barrio de Santiago

Nicholas

includes taxes & fees

6 Oct - 7 Oct

A blue door with a window, surrounded by lush green foliage.

11. Merida Santiago Hotel Boutique

Barrio de Santiago

Rubi

includes taxes & fees

6 Oct - 7 Oct

A courtyard with arches, potted plants, a fountain, and a tiled floor.

12. Hotel Boutique La Casona By Kavia

Barrio de Santiago

Corina

includes taxes & fees

6 Oct - 7 Oct

13. Kuxtal Hotel Boutique

Barrio de Santiago

Rogelio

includes taxes & fees

13 Oct - 14 Oct

A pool area with clear water, stone walls, and blue and white architecture.

14. Hotel Casa Azuli

Barrio de Santiago

David

includes taxes & fees

31 Oct - 1 Nov

A futuristic interior with geometric patterns and illuminated blue lines on the walls.

15. Kapsul Express Mérida

Barrio de Santiago

Regina

includes taxes & fees

6 Oct - 7 Oct

An indoor swimming pool with a long, narrow shape, surrounded by lush greenery and a seating area.

16. Casa Querida

Barrio de Santiago

Herik

includes taxes & fees

6 Oct - 7 Oct

A pool surrounded by lush greenery and a traditional building with arched windows.

17. Kunuk Hotel Boutique

Barrio de Santiago

Victor

includes taxes & fees

6 Oct - 7 Oct

Two single beds with wooden frames and white bedding, a small round table, and a patterned rug on a tiled floor.

18. Casa XUVA

Barrio de Santiago

includes taxes & fees

6 Oct - 7 Oct

A spa area with a rectangular hot tub, bamboo wall, and a stone wall.

19. Casa de Cortes

Barrio de Santiago

Yajaira

includes taxes & fees

7 Oct - 8 Oct

A spacious lobby with a green ottoman, a chandelier, and a large painting.

20. Hotel Residencial

Barrio de Santiago

Julio César

includes taxes & fees

6 Oct - 7 Oct

View all properties

Compare popular hotels in Barrio de Santiago

Property	Property class	Guest rating
Merida Santiago Hotel Boutique	4.0 star property	10.0 Exceptional 172 reviews	View
The Diplomat Boutique Hotel	4.0 star property	10.0 Exceptional 50 reviews	View
Casa Querida	3.0 star property	10.0 Exceptional 9 reviews	View
Casa Tunkul	2.0 star property	9.8 Exceptional 11 reviews	View
Casa Loreto 1893	5.0 star property	9.8 Exceptional 173 reviews	View

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas for the activities you enjoy most.

A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

The core of the White City is a fusion of Mayan ruins, Spanish colonial churches and intriguing galleries and museums.

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A sunset over a body of water with a rocky shoreline.

Chelem

If you're spending some time in Chelem, Chelem Park is a top sight worth visiting.

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A historic building with ornate architecture, palm trees, and well-maintained landscaping.

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

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A row of boats on a beach with a sunset in the background.

Chicxulub Puerto

Travellers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

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A meal with tacos, a salad, and a drink at a restaurant.

Santa Lucia

If you're looking for some top things to see and do in Santa Lucia and surrounding area, you can visit Plaza Grande and Paseo 60.

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Top Barrio de Santiago Hotel Reviews

Gran Hotel Panamericana Merida

10/10 Excellent

"It was in a good area and everyone was polite and it was more chill vibes"

Casa Aura Hotel, Mérida

10/10 Excellent

"I stayed at Casa Aura for a few days during my trip to Mérida and would absolutely stay here again. This is not a luxury boutique hotel, but it is comfortable, welcoming, quiet at night, and in a great location. What stood out the most to me was the staff. Everyone was incredibly friendly, helpful, and accommodating. Whenever I needed something, they found a way to help. My room had everything I needed: A/C, Wi-Fi, TV, a hairdryer, toiletries, towels and space to hang my clothes. When the room felt a little cold for me, I asked for an extra blanket and they took care of it. There was always someone available at the front, which also made me feel comfortable coming and going. I arrived around 8 p.m. and had no problem checking in. I really enjoyed the pool and the continental breakfast, especially sitting outside surrounded by all the greenery. It was such a peaceful way to start the morning. The location was another big plus. I walked all over Mérida from here—to Paseo de Montejo, nearby streets, parks and other areas I wanted to explore. I rarely felt like I needed transportation. One suggestion: bring mosquito repellent! With the beautiful plants and tropical setting, mosquitoes can get into the room if you leave the door open. For approximately $60 a night when I stayed, I thought it was a very good value. It felt simple, comfortable and relaxed, and the kindness of the staff made my stay even better. I would definitely return."

Hotel Casa Azuli

10/10 Excellent

"This is not a reflection on the hotel but rather on the guests. I think a noise/party schedule would be helpful. Some guests where using the pool at midnight while listening to music and chatting and drinking. During normal hours that would be ok. The space between the pool and the rooms is small so noises easily carry onto the rooms. Customers should be made aware to be respectful of other guests comfort."

Hotels in Barrio de Santiago

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Our top choices for Barrio de Santiago hotels

1. Casa Aura Hotel, Mérida

2. Hotel Casa 57

3. Casona 61 Boutique Hotel

4. Hotel Unknown

5. Casa Tunkul

6. Hotel Ambassador Merida

7. Hotel Zamna

8. Casa Loreto 1893

9. Viva Merida Hotel Boutique

10. The Diplomat Boutique Hotel

11. Merida Santiago Hotel Boutique

12. Hotel Boutique La Casona By Kavia

13. Kuxtal Hotel Boutique

14. Hotel Casa Azuli

15. Kapsul Express Mérida

16. Casa Querida

17. Kunuk Hotel Boutique

18. Casa XUVA

19. Casa de Cortes

20. Hotel Residencial

Compare popular hotels in Barrio de Santiago

Where to stay in Barrio de Santiago

Mérida Centro

Chelem

Zona Paseo Montejo

Chicxulub Puerto

Santa Lucia

Top Barrio de Santiago Hotel Reviews

Gran Hotel Panamericana Merida

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