Photo by Majid Shaheen

Hotels in Central San Mateo

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Central San Mateo hotels

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
3.0 star property
Central San Mateo
7.8 out of 10, Good, (1022)
"Yes, room was clean, staff very kind. "
United States
Jesus
The price is S$146
includes taxes & fees
23 Jan - 24 Jan, 2026
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC
2.0 star property
Central San Mateo
The price is S$654
includes taxes & fees
1 Jan - 2 Jan, 2026
Sanmateo Cozy Central 3b1b Home Garage Parking AC

@ Marbella Lane - Bright and Cozy Home Near SFO

@ Marbella Lane - Bright and Cozy Home Near SFO
3.0 star property
Central San Mateo
The price is S$1,353
includes taxes & fees
13 Jan - 14 Jan, 2026
@ Marbella Lane - Bright and Cozy Home Near SFO

The Nest Hotel Palo Alto

The Nest Hotel Palo Alto
3.5 star property
23.7 km from Central San Mateo
9.0 out of 10, Wonderful, (1002)
"Great hotel, great staff "
United States
jimmy
The price is S$168
includes taxes & fees
1 Jan - 2 Jan, 2026
The Nest Hotel Palo Alto

Creekside Inn

Creekside Inn
3.5 star property
23.2 km from Central San Mateo
9.0 out of 10, Wonderful, (1654)
"A lovely spot in Palo Alto - good value and location. Will stay there again!"
United States
Martha
The price is S$149
includes taxes & fees
3 Jan - 4 Jan, 2026
Creekside Inn

Hampton Inn & Suites Mountain View

Hampton Inn & Suites Mountain View
2.5 star property
28.6 km from Central San Mateo
9.0 out of 10, Wonderful, (971)
"Nice place to stay"
United States
Douglas R.
The price is S$138
includes taxes & fees
2 Jan - 3 Jan, 2026
Hampton Inn & Suites Mountain View

Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica
2.5 star property
15.9 km from Central San Mateo
8.2 out of 10, Very good, (1000)
"Second time staying here and it was perfect for a quick weekend get away. The location is excellent and the staff is so kind and helpful. "
United States
Kristin
Inn at Rockaway San Francisco Pacifica

The Ameswell Hotel

The Ameswell Hotel
4.5 star property
28.6 km from Central San Mateo
9.6 out of 10, Exceptional, (1154)
"Beautiful hotel with great service "
Australia
Amanda
The price is S$185
includes taxes & fees
1 Jan - 2 Jan, 2026
The Ameswell Hotel

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
27.3 km from Central San Mateo
9.4 out of 10, Exceptional, (1221)
"Perfect place to stay and enjoy "
United States
Ali
The price is S$211
includes taxes & fees
1 Jan - 2 Jan, 2026
Shashi Hotel Mountain View Palo Alto

The Zen Hotel Palo Alto

The Zen Hotel Palo Alto
3.0 star property
24.4 km from Central San Mateo
9.2 out of 10, Wonderful, (1297)
"Spotless room, wonderful staff, nice breakfast, and great location."
United States
Karen
The price is S$126
includes taxes & fees
1 Jan - 2 Jan, 2026
The Zen Hotel Palo Alto

Menlo Park Inn

Menlo Park Inn
3.0 star property
17.1 km from Central San Mateo
9.0 out of 10, Wonderful, (1004)
"We've stayed here a few times and have always been happy with our choice. Friendly owners, good breakfast"
United States
Evan
The price is S$129
includes taxes & fees
3 Jan - 4 Jan, 2026
Menlo Park Inn

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
19.2 km from Central San Mateo
8.6 out of 10, Excellent, (2306)
"Clean, cozy, great staff!"
United States
Stacie
The Marina Inn on San Francisco Bay

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.4 km from Central San Mateo
8.8 out of 10, Excellent, (2020)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is S$190
includes taxes & fees
2 Jan - 3 Jan, 2026
The Westin San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.4 km from Central San Mateo
9.0 out of 10, Wonderful, (2229)
"Spotless — not fancy but clean open and comfortable !!! Great airport hotel!!!!"
United States
Michael
The price is S$166
includes taxes & fees
1 Jan - 2 Jan, 2026
Aloft San Francisco Airport

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
17 km from Central San Mateo
9.0 out of 10, Wonderful, (1090)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is S$188
includes taxes & fees
5 Jan - 6 Jan, 2026
Half Moon Bay Lodge

Executive Inn & Suites Embarcadero Cove

Executive Inn & Suites Embarcadero Cove
3.0 star property
25.7 km from Central San Mateo
9.0 out of 10, Wonderful, (1003)
"Good breakfast "
United States
zhijun
The price is S$189
includes taxes & fees
18 Jan - 19 Jan, 2026
Executive Inn & Suites Embarcadero Cove

Hyatt Place Newark/Silicon Valley

Hyatt Place Newark/Silicon Valley
3.0 star property
29.6 km from Central San Mateo
9.0 out of 10, Wonderful, (733)
"It’s great place to stay for family vacation. "
United States
shujia
The price is S$160
includes taxes & fees
11 Jan - 12 Jan, 2026
Hyatt Place Newark/Silicon Valley

Chase Suite Hotel Newark-Fremont

Chase Suite Hotel Newark-Fremont
3.5 star property
28.5 km from Central San Mateo
8.6 out of 10, Excellent, (1001)
"great place to stay "
United States
dan
Chase Suite Hotel Newark-Fremont

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
11.2 km from Central San Mateo
8.6 out of 10, Excellent, (1005)
"Great hospitality staff is awesome will definitely stay here again !!"
United States
Cindy
The price is S$133
includes taxes & fees
3 Jan - 4 Jan, 2026
Hotel Nova SFO

La Quinta Inn & Suites by Wyndham Oakland - Hayward

La Quinta Inn & Suites by Wyndham Oakland - Hayward
3.0 star property
21.5 km from Central San Mateo
8.4 out of 10, Very good, (1103)
"The stay was nice. Ample parking and the room was clean. "
United States
curt
The price is S$129
includes taxes & fees
29 Jan - 30 Jan, 2026
La Quinta Inn & Suites by Wyndham Oakland - Hayward
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.

Union Square

Fashion puts its best foot forward in this vast shopping plaza.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Dating back to the middle of the 19th Century, this historic wharf has been through many incarnations. Today it’s bursting with fun, sea lions and restaurants.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Central San Mateo Hotel Reviews

Frequently asked questions

What is Central San Mateo like?
You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.
What's a favourite place to stay in Central San Mateo?
Based on Expedia customer reviews, Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG is the highest ranked property in Central San Mateo. This hotel offers a restaurant and a 24-hour fitness centre.
How many hotels will I find in the Central San Mateo area?
Expedia has 44 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.
What is there to do in this San Mateo neighbourhood?
A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Burlingame Museum of PEZ Memorabilia and Poplar Creek Golf Course are a couple of additional sights to visit in San Mateo.
How can I get around Central San Mateo and the greater San Mateo area?
If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.

Explore a world of travel with Expedia