𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Charleston (2026)

A sunset over a calm lake with tall trees reflected in the water.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Charleston

Pet friendly

Apartment

Pool

Family friendly

Waterpark

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Charleston hotels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

S$84

includes taxes & fees

7 Oct - 8 Oct

A building with a fountain and flower beds in front.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

2. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

S$95

includes taxes & fees

8 Oct - 9 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

3. Eagle Inn Charleston

Charleston

Jackson

S$94

includes taxes & fees

7 Oct - 8 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

S$138

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

5. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

S$93

includes taxes & fees

7 Oct - 8 Oct

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

6. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

S$146

includes taxes & fees

15 Oct - 16 Oct

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

7. Best Western Plus Sikeston I-55

Sikeston

Shelley

S$122

includes taxes & fees

11 Oct - 12 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

8. Hampton Inn Sikeston

Sikeston

Carolyn

S$153

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

9. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

S$147

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

10. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

S$152

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

11. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

S$97

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

12. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

S$83

includes taxes & fees

14 Oct - 15 Oct

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A hotel room with two beds, a desk, a chair, and a view of the city.

13. The Riverview

Cape Girardeau

Alyssa

S$152

includes taxes & fees

7 Oct - 8 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

14. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

S$144

includes taxes & fees

11 Oct - 12 Oct

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

15. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

S$121

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a counter, a coffee machine, and seating.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

16. Country Yard Inn and Suite

Sikeston

William

S$86

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

17. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

S$133

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, seating area, and a large window.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

18. Quality Inn Cairo I-57

Cairo

Santiago

S$97

includes taxes & fees

23 Oct - 24 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

19. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

S$146

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

20. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

S$104

includes taxes & fees

11 Oct - 12 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Learn more about Charleston

Quaint Charleston is calling! Discover its opera, entertainment, cathedral and more.

See all hotels in Charleston

Top Charleston Hotel Reviews

Hampton Inn Sikeston

10/10 Excellent

"Clean, safe, quiet and a very good breakfast."

The Riverview

10/10 Excellent

"We were passing through and pleasantly surprised! Clean, well appointed, super friendly staff - everyone seemed happy t work there, and all around great. A real Starbucks in the lobby plus extra security because of the casino in the parking lot were huge plusses. 😊"

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Perfect location, beds were awesome & staff were friendly & accommodating!"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"No exhaust fan in the bathroom. Other than that very clean comfortable hotel"

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"Great place"

Candlewood Suites Cape Girardeau by IHG

8/10 Good

"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, but missing a rather large blood stain on the wall behind the door is disturbing. Thankfully I always travel with Lysol wipes and cleaned it up."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"NA NA NA NA NA NA NA NA NA NA NA NA NA"

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

More cheap stays in Charleston

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

S$83

14 Oct - 15 Oct

includes taxes & fees

7/10 Good! (682 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

S$97

1 Nov - 2 Nov

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

S$104

11 Oct - 12 Oct

includes taxes & fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

S$122

11 Oct - 12 Oct

includes taxes & fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

S$130

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (1,001 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

S$147

11 Oct - 12 Oct

includes taxes & fees

9.4/10 Exceptional! (1,004 reviews)

Frequently asked questions

Where is the best place for a stay in Charleston?

Based on our traveller data, The Riverstone Hotel Charleston-Sikeston is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good options for your trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See all available top hotels, or vacation rentals in Charleston.

If I need to cancel my hotel reservation in Charleston, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Charleston.

What is the top LGBTQ-friendly accommodation in Charleston?

The Riverstone Hotel Charleston-Sikeston is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Charleston.

What's the best dog-friendly accommodation option in Charleston?

The Riverstone Hotel Charleston-Sikeston is a top dog-friendly hotel, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good options to stay with your pet include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See more pet-friendly hotel accommodations in Charleston.

How is it staying in Charleston?

Visitors to Charleston will definitely enjoy the restaurants. Tourists can also enjoy the city's entertainment choices, theatres and churches. In Charleston, there are 3 hotels and other accommodation options to choose from. Find out more about Charleston.

What should I do while I'm visiting Charleston?

The picturesque setting of Mississippi River and Ohio River exemplify the area's natural beauty. You'll also find Ballard Wildlife Management Area and Columbus-Belmont State Park in the area. Take a look at what more there is to see and do in Expedia's Charleston guide.

What's the seasonal weather like in Charleston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Charleston is 1509 mm.

Charleston Hotels from S$83

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Charleston

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Charleston hotels

1. Super 8 by Wyndham Charleston/Sikeston East MO

2. The Riverstone Hotel Charleston-Sikeston

3. Eagle Inn Charleston

4. Drury Inn & Suites Sikeston, MO

5. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

6. Fairfield Inn & Suites by Marriott Sikeston

7. Best Western Plus Sikeston I-55

8. Hampton Inn Sikeston

9. Holiday Inn Express & Suites Sikeston Southwest by IHG

10. TownePlace Suites by Marriott Sikeston

11. Days Inn and Suites by Wyndham Sikeston

12. Super 8 by Wyndham Sikeston/Miner Area

13. The Riverview

14. Drury Plaza Hotel Cape Girardeau Conference Center

15. Comfort Inn & Suites Sikeston I-55

16. Country Yard Inn and Suite

17. Drury Inn & Suites Cape Girardeau

18. Quality Inn Cairo I-57

19. Fairfield Inn & Suites by Marriott Cape Girardeau

20. Pear Tree Inn Cape Girardeau West

Learn more about Charleston

Top Charleston Hotel Reviews

Hampton Inn Sikeston

The Riverview

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Cape Girardeau

Super 8 by Wyndham Sikeston/Miner Area

Candlewood Suites Cape Girardeau by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

More cheap stays in Charleston

Super 8 by Wyndham Sikeston/Miner Area

Days Inn and Suites by Wyndham Sikeston

Pear Tree Inn Cape Girardeau West

Best Western Plus Sikeston I-55

Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app