East Prairie Hotels from S$73

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24 Aug - 25 Aug
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25 Aug - 26 Aug
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29 Aug - 31 Aug
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5 Sept - 7 Sept

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Top 10 trending East Prairie hotels

Our top choices for East Prairie hotels

Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1003)
"The room was awesome and the building had a historical thing about it."
The price is S$92
includes taxes & fees
1 Sept - 2 Sept
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston
Exterior

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (375)
"Great location and clean room. Plenty of food and shopping nearby."
The price is S$154
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (423)
"Close in eating and shopping "
The price is S$152
includes taxes & fees
12 Sept - 13 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG
Super 8 by Wyndham Sikeston/Miner Area
Desk, laptop workspace, blackout curtains, free WiFi

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (552)
"I enjoyed our stay"
The price is S$92
includes taxes & fees
26 Aug - 27 Aug
Super 8 by Wyndham Sikeston/Miner Area
Best Western Plus Sikeston
Free daily full breakfast

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1003)
"Staff was friendly and room was very clean. A very comfortable stay"
The price is S$123
includes taxes & fees
14 Sept - 15 Sept
Best Western Plus Sikeston
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Very nice property Friendly helpful staff"
The price is S$113
includes taxes & fees
4 Sept - 5 Sept
Pear Tree Inn Sikeston
Sleep Inn at Discovery Park of America
Lobby

Sleep Inn at Discovery Park of America

2.5 star property
9.0 out of 10, Wonderful, (264)
"This place must be brand new, the pillows and bed were perfect, everything was spotlessly clean, and the complementary breakfast was wonderful!"
The price is S$128
includes taxes & fees
7 Sept - 8 Sept
Sleep Inn at Discovery Park of America
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property – evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (585)
"Rooms was clean "
The price is S$82
includes taxes & fees
8 Sept - 9 Sept
Super 8 by Wyndham Charleston/Sikeston East MO
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hallway

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very good, (669)
"Everything was nice"
The price is S$73
includes taxes & fees
27 Aug - 28 Aug
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Comfort Inn & Suites Sikeston I-55
Exterior

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very good, (271)
"The facility was very nice. "
The price is S$129
includes taxes & fees
31 Aug - 1 Sept
Comfort Inn & Suites Sikeston I-55
Hospitality House Union City I 69 / US 51
Seasonal outdoor pool

Hospitality House Union City I 69 / US 51

2.5 star property
6.8 out of 10, (327)
"The Staff"
The price is S$83
includes taxes & fees
22 Sept - 23 Sept
Hospitality House Union City I 69 / US 51
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is S$98
includes taxes & fees
11 Sept - 12 Sept
Quality Inn Cairo I-57
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Great location "
The price is S$133
includes taxes & fees
1 Sept - 2 Sept
Drury Inn & Suites Sikeston, MO
Quality Inn Union City US 51
Lobby

Quality Inn Union City US 51

2.5 star property
8.4 out of 10, Very good, (463)
"Quite, clean, and good location."
The price is S$122
includes taxes & fees
14 Sept - 15 Sept
Quality Inn Union City US 51
Fairfield Inn & Suites by Marriott Sikeston
Bar (on property)

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (18)
"Nice hotel "
The price is S$165
includes taxes & fees
7 Sept - 8 Sept
Fairfield Inn & Suites by Marriott Sikeston
New Orleans Inn Portageville
1 bedroom, desk, free WiFi, bed sheets

New Orleans Inn Portageville

2.5 star property
8.0 out of 10, Very good, (685)
"Very nice stay"
New Orleans Inn Portageville
Holiday Inn Express & Suites Union City by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Union City by IHG

2.5 star property
9.4 out of 10, Exceptional, (287)
"This hotel was directly across from the Discovery Park of America. Definitely recommend staying there!"
The price is S$177
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Express & Suites Union City by IHG
Travel Inn
Gazebo

Travel Inn

2.5 star property
5.8 out of 10, (108)
"Great place"
Travel Inn
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (398)
"I consistently choose to stay there due to positive past encounters."
The price is S$96
includes taxes & fees
8 Sept - 9 Sept
Quality Inn Charleston - Sikeston
Country Hearth Inn & Suites Union City
Reception

Country Hearth Inn & Suites Union City

2.5 star property
8.6 out of 10, Excellent, (530)
"Very good!"
The price is S$110
includes taxes & fees
26 Aug - 27 Aug
Country Hearth Inn & Suites Union City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie

Top East Prairie Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Staff was very friendly and helpful."
Rebecca 1-night trip
Posted 1 day ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

What's the best place for a stay in East Prairie?

Best Western Plus Sikeston, located 11.1 mi (17.9 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Drury Inn & Suites Sikeston, MO and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.

If I need to cancel my hotel reservation in East Prairie, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

How is it staying in East Prairie?

Visitors will definitely enjoy all that East Prairie has to offer. There are 30 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.

What are the top places to visit in East Prairie?

The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.

What's the weather like in East Prairie?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.