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Hotels near Florida Keys National Marine Sanctuary

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Check prices for these dates

Tonight
1 Sept - 2 Sept
Tomorrow
2 Sept - 3 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

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Our top choices for Florida Keys National Marine Sanctuary hotels

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
John
S$241
includes taxes & fees
8 Sept - 9 Sept
Almond Tree Inn Hotel - Adults Only

2. The Gardens Hotel

The Gardens Hotel
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Brian
S$288
includes taxes & fees
15 Sept - 16 Sept
The Gardens Hotel

3. Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
United States
RAFAEL
S$189
includes taxes & fees
8 Sept - 9 Sept
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

4. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
United States
Nicholas
S$206
includes taxes & fees
2 Sept - 3 Sept
Orchid Key Inn - Adults Only

5. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
United States
Robin
S$185
includes taxes & fees
2 Sept - 3 Sept
Simonton Court Historic Inn & Cottages

6. The Marquesa Hotel

The Marquesa Hotel
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
Darrell
S$395
includes taxes & fees
21 Sept - 22 Sept
The Marquesa Hotel

7. The Porch on Frances Inn

The Porch on Frances Inn
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Corrynne
S$205
includes taxes & fees
7 Sept - 8 Sept
The Porch on Frances Inn

8. Duval House

Duval House
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Robert
S$158
includes taxes & fees
16 Sept - 17 Sept
Duval House

9. The Conch House Heritage Inn

The Conch House Heritage Inn
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
United States
John
S$272
includes taxes & fees
2 Sept - 3 Sept
The Conch House Heritage Inn

10. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
United States
Shermeka
S$445
includes taxes & fees
9 Sept - 10 Sept
H2O Suites - Adults Only

11. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
United States
Kyle
S$161
includes taxes & fees
9 Sept - 10 Sept
Douglas House - Adults Only

12. Island City House Hotel

Island City House Hotel
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Paul
S$226
includes taxes & fees
16 Sept - 17 Sept
Island City House Hotel

13. Tropical Inn

Tropical Inn
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Joel
S$211
includes taxes & fees
2 Sept - 3 Sept
Tropical Inn

14. The Mermaid & Alligator

The Mermaid & Alligator
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
United States
Johnny
S$281
includes taxes & fees
15 Sept - 16 Sept
The Mermaid & Alligator

15. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Travis
S$204
includes taxes & fees
3 Sept - 4 Sept
The Grand Guesthouse

16. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
United States
June Young
S$485
includes taxes & fees
7 Sept - 8 Sept
Santa Maria Suites

17. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
United States
Shawn
S$181
includes taxes & fees
2 Sept - 3 Sept
Silver Palms Inn & Historic Homes

18. Westwinds Inn

Westwinds Inn
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
United States
John
S$200
includes taxes & fees
2 Sept - 3 Sept
Westwinds Inn

19. Coco Plum Inn

Coco Plum Inn
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
United States
Jake
S$240
includes taxes & fees
7 Sept - 8 Sept
Coco Plum Inn

20. Ambrosia Key West

Ambrosia Key West
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United Kingdom
Kate
S$244
includes taxes & fees
2 Sept - 3 Sept
Ambrosia Key West
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only
10.0
Exceptional
1,008 reviews
View
Exterior detail
The Gardens Hotel
9.8
Exceptional
1,003 reviews
View
Free WiFi, bed sheets
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
9.8
Exceptional
163 reviews
View
Property grounds
Orchid Key Inn - Adults Only
9.8
Exceptional
1,004 reviews
View
Minibar, in-room safe, iron/ironing board, free WiFi
Simonton Court Historic Inn & Cottages
9.8
Exceptional
1,001 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

10/10 Excellent
"Highly recommend!"
Paul 2-night trip
Posted 3 hours ago
Opal Key Resort & Marina, Key West
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

8/10 Good
"This was a great location and stay, and the front desk guy was the best! My only issue was constant crowing of roosters and they are all around the property and the lights are left on outside at night making it seem like daylight outside"
Michelle 4-night trip
Posted 9 hours ago
The Cabana Inn Key West - Adults Only
Duval House

Duval House

10/10 Excellent
"Staff are all very kind, included breakfast was great, and resort was quaint and well kept. We will stay here again."
Robert 4-night trip
Posted 12 hours ago
Duval House
Douglas House - Adults Only

Douglas House - Adults Only

10/10 Excellent
"Great location in the Keys, The staff was extremely helpful. Overall it was a great experience"
Marc 2-night trip
Posted 13 hours ago
Douglas House - Adults Only
Lighthouse Hotel - Key West Historic Inns

Lighthouse Hotel - Key West Historic Inns

10/10 Excellent
"Great boutique hotel! The room was clean, the bed was very comfortable, and the location was perfect—just one block from Duval Street, with restaurants nearby. Breakfast was also better than I expected! Live music by the pool (afternoon and during breakfast) and at night was very quiet! Overall, a very pleasant stay!"
gabriela 3-night trip
Posted 1 day ago
Lighthouse Hotel - Key West Historic Inns
Pier House Resort & Spa

Pier House Resort & Spa

10/10 Excellent
"Best Hotel in the Key West. Room was very clean, best staff services. Beautiful beach view and breakfast was delicious. My husband and I love this place. 💯 recommend."
Vivian 1-night trip
Posted 1 day ago
Pier House Resort & Spa
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

10/10 Excellent
"Had an issue with the door on the last day, but they rectified the problem. Stay was quite pleasant. Enjoyed immensely will be back in January."
Clay 4-night trip
Posted 2 days ago
The Reach Key West, Curio Collection by Hilton
Weatherstation Inn

Weatherstation Inn

10/10 Excellent
"We really enjoyed our stay here. Nice rooms and breakfast was nice to have available. Will definitely stay here on our next trip."
Elizabeth 3-night trip
Posted 3 days ago
Weatherstation Inn
Coco Plum Inn

Coco Plum Inn

10/10 Excellent
"The pool is so topically beautiful and clean!! Room was cool and comfortable!! Will definitely be back!"
Shaun 5-night trip
Posted 4 days ago
Coco Plum Inn

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
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A brick corridor with arched ceilings and benches.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
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The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a trip to Jackson Square. Stroll along the beautiful beaches or discover the area's beautiful sunsets.
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Coffee Butler Amphitheater

You can make plans for a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its great live music.
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USCGC Ingham Maritime Museum

You can spend an afternoon browsing the exhibits at USCGC Ingham Maritime Museum during your trip to Key West.
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Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its great live music.
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We Cycle Key West

You can do some window-shopping at We Cycle Key West during your stay in Key West.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1492 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveller data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1492 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater and Key West Film Society if you're interested in local theatre.