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Hotels near Florida Keys National Marine Sanctuary

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Check prices for these dates

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Florida Keys National Marine Sanctuary hotels

A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.
A swimming pool with lounge chairs, surrounded by palm trees and greenery.
A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.
A building with a sign reading "ALMOND Frog & Toad Inn" and a "VACANCY" sign below it.

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
John
S$402
includes taxes & fees
27 Oct - 28 Oct
Almond Tree Inn Hotel - Adults Only
A modern interior with a staircase, a sofa set, a wooden table, and a television.
A spacious room with a large bed, a sofa, a chair, a small table, and a television.
A pool area with a clear view of a house in the background, surrounded by palm trees and greenery.
A pathway flanked by lush green foliage leading to a gated entrance.

2. Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
United States
William
S$244
includes taxes & fees
25 Oct - 26 Oct
Simonton Court Historic Inn & Cottages
A tropical outdoor area with palm trees, hanging plants, and string lights.
A wooden deck with lush greenery and a pool area.
A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.
An outdoor patio with a table and chairs, surrounded by lush greenery and string lights.

3. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
United States
Maricela
S$250
includes taxes & fees
19 Oct - 20 Oct
Douglas House - Adults Only
A modern outdoor area with a pool, lounge chairs, and a bar area.
A modern hotel with a prominent glass facade, palm trees, and a clear sky.
A modern hotel room with a bed, sofa, coffee table, and artwork.
An outdoor seating area with a modern fire feature, surrounded by lush greenery and palm trees.

4. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
United States
Corey
S$591
includes taxes & fees
2 Nov - 3 Nov
H2O Suites - Adults Only
A pool area with lounge chairs and a table, surrounded by palm trees.
A hotel room with a large bed, a nightstand, a desk, a bathroom with a shower, and a painting of a pier over water on the wall.
A building with a neon sign that reads "Orchid Key Inn."
A neon sign for Orchid Key Inn with a 'VACANCY' sign below it.

5. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
United States
ben
S$367
includes taxes & fees
27 Oct - 28 Oct
Orchid Key Inn - Adults Only
A garden pathway leading to a white gazebo with pink flowers, surrounded by lush greenery and a white fence.
A colonial-style building with a porch, surrounded by lush tropical vegetation.
A bedroom with a large bed, a television on a dresser, and a view of the outdoors through a sliding door.
A couple walking along a poolside pathway surrounded by lush greenery.

6. The Gardens Hotel

The Gardens Hotel
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Gisele
S$486
includes taxes & fees
27 Oct - 28 Oct
The Gardens Hotel
A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.
A two-story building with a porch, a sign reading "The Grand Guesthouse," and a purple flag.
A bedroom with a bed, nightstand, lamp, air conditioning unit, and a no smoking sign.
A covered outdoor area with a wooden staircase, seating, and potted plants.

7. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Justyn
S$260
includes taxes & fees
27 Oct - 28 Oct
The Grand Guesthouse
A wooden deck with a hammock, pool, and lounge chairs overlooking a tropical garden.
A garden with a pond, rocks, and various plants.
A compact kitchen with wooden cabinets, a microwave, stove, and refrigerator. There is a dining area with a table and chairs, and a sofa.
A pool area with lounge chairs and a wooden building with balconies.

8. Island City House Hotel

Island City House Hotel
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Elise
S$322
includes taxes & fees
25 Oct - 26 Oct
Island City House Hotel
A pool area with lounge chairs and palm trees.
A neatly made bed with patterned pillows, a bedside table with a bottle and glasses, and a window with orchids.
A sign for Santa Maria Resort surrounded by lush greenery and palm trees.
A modern outdoor seating area with a sofa, chairs, and a small table, surrounded by glass doors and a view of greenery.

9. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
United States
Anthony
S$519
includes taxes & fees
26 Oct - 27 Oct
Santa Maria Suites
A swimming pool with water splashing, surrounded by palm trees and a building in the background.
The entrance to Silver Palms Inn with a reception desk, a seating area, and a glass door.
The exterior of the Silver Palms Inn with a two-story structure, a green awning over the entrance, and a palm tree to the right.
A two-story yellow house with a porch, white railings, and green shutters.

10. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
United States
sam
S$215
includes taxes & fees
25 Oct - 26 Oct
Silver Palms Inn & Historic Homes
A reception area with a curved marble counter, ceiling fans, large windows, and a staircase.
A breakfast table with a variety of food items, including fruits, pastries, and a coffee mug.
A poolside area with lounge chairs and a clear blue pool surrounded by lush tropical vegetation.
A bedroom with a bed, two bedside lamps, a ceiling fan, and a view of a balcony with plants.

11. Westwinds Inn

Westwinds Inn
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
United States
Anthony
S$234
includes taxes & fees
25 Oct - 26 Oct
Westwinds Inn
A large, ornate hotel with a pool, palm trees, and a view of the ocean.
A large, two-story house with a prominent tower and a covered porch.
A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.
A gated entrance with a blue metal gate, palm trees, and a building with a red roof in the background.

12. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
United States
Amy
S$421
includes taxes & fees
25 Oct - 26 Oct
Southernmost House - Adult Exclusive
A rectangular pool with a white deck, surrounded by lush greenery and a gazebo.
A wicker outdoor seating area with two chairs and a table, surrounded by lush tropical foliage.
A spacious living room with a high ceiling, a ceiling fan, a large painting, a sofa, a coffee table, and a dining area with a table and chairs.
A hotel room with a bed, a nightstand, a chair, a small table, and a ceiling fan.

13. Ambrosia Key West

Ambrosia Key West
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
RICHARD
S$369
includes taxes & fees
26 Oct - 27 Oct
Ambrosia Key West
A room with a door featuring horizontal blinds, a visible outdoor view through the window, and a patterned carpet.
A pool area with a circular pool, lounge chairs, and a gazebo.
A garden with a stone pathway, a wooden fence, and various tropical plants.
A room with a bed, a desk, a chair, a lamp, a painting of a boat on water, and a view of the sea.

14. Alexander Palms Court

Alexander Palms Court
Casa Marina, 1.4 km from Florida Keys National Marine Sanctuary
United States
Andrew
S$325
includes taxes & fees
19 Oct - 20 Oct
Alexander Palms Court
A gated entrance with lush green foliage and a white picket fence.
A white colonial-style building with a balcony, surrounded by palm trees and a white picket fence.
A swimming pool with lounge chairs, a covered deck, and a view of lush greenery.
A covered outdoor dining area with white chairs and tables, surrounded by lush greenery and a wooden deck.

15. Coco Plum Inn

Coco Plum Inn
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
United States
Riley
S$289
includes taxes & fees
18 Oct - 19 Oct
Coco Plum Inn
A hotel with a covered entrance, multiple balconies, and palm trees.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A waterfront hotel with multiple balconies, a dock, and boats.

16. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Susan
S$424
includes taxes & fees
18 Oct - 19 Oct
Opal Key Resort & Marina, Key West
A large, white, two-story building with a balcony and a sign reading "The Marker Resort."
A marina with various boats docked, including a green and white boat named 'Jolly Roger'.
A tropical setting with palm trees and a building with a white facade and dark roof.
A covered outdoor area with a pool, palm trees, and lounge chairs.

17. The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
Historic Seaport, 1.3 km from Florida Keys National Marine Sanctuary
United States
Lynne
S$352
includes taxes & fees
25 Oct - 26 Oct
The Marker Key West Harbor Resort
A building with a white exterior, a large red awning, and a gated entrance.
A small, enclosed porch with a chair and a table, surrounded by lush greenery and a white lattice fence.
A paved pathway lined with various plants and trees, leading to a building with a beige exterior.
A spacious kitchen with a dining area, large windows, and a view of the outdoors.

18. Authors of Key West Guest House

Authors of Key West Guest House
The Meadows, 1.8 km from Florida Keys National Marine Sanctuary
United States
Robbie
S$220
includes taxes & fees
27 Oct - 28 Oct
Authors of Key West Guest House
Lobby
Room
A covered outdoor area with a pool, wicker furniture, and a red umbrella.
A two-story building with a balcony, a flag, and a palm tree.

19. The Independent Inn - Formerly Heron House Court

The Independent Inn - Formerly Heron House Court
Historic Seaport, 1.6 km from Florida Keys National Marine Sanctuary
United States
Michael
S$211
includes taxes & fees
18 Oct - 19 Oct
The Independent Inn - Formerly Heron House Court
A pool area with lounge chairs and a cabana.
A waterfront hotel with a long pier, multiple balconies, and a view of the ocean.
A hotel room with a bed, a sofa, a desk with a computer, a chair, and a view of the sea through large windows.
A dining area with a glass table, clear glass bottles, a bowl of fruit, and a wicker chair.

20. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Patrick
S$508
includes taxes & fees
29 Oct - 30 Oct
Ocean Key Resort - A Noble House Resort
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Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.
Almond Tree Inn Hotel - Adults Only
10.0
Exceptional
1,005 reviews
View
A modern interior with a staircase, a sofa set, a wooden table, and a television.
Simonton Court Historic Inn & Cottages
9.8
Exceptional
1,002 reviews
View
A tropical outdoor area with palm trees, hanging plants, and string lights.
Douglas House - Adults Only
9.8
Exceptional
557 reviews
View
A modern outdoor area with a pool, lounge chairs, and a bar area.
H2O Suites - Adults Only
9.8
Exceptional
667 reviews
View
A pool area with lounge chairs and a table, surrounded by palm trees.
Orchid Key Inn - Adults Only
9.8
Exceptional
1,005 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

10/10 Excellent
"We enjoyed the King Suite. Especially the modern updated ensuite. The pool and hot tub were fantastic in a unique private setting with ample palm trees and greenery."
Camiel 3-night trip
Posted 7 hours ago
The Southernmost Inn - Adults Only
Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns

10/10 Excellent
"Amazing stay! Would highly recommend!"
Courtney 1-night trip
Posted 8 hours ago
Winslow's Bungalows - Key West Historic Inns
Pier House Resort & Spa

Pier House Resort & Spa

8/10 Good
"The location of the property was great for our visit because we had a couple of excursions from the pier not too far. The property was really nice and we enjoyed having the beach to be able to get in the ocean after a hot day. Food and drinks at the hotel were great. The only complaint I have is in our room there was only 1 tabletop lamp and only one in the sitting area so it was real hard to see when trying to get ready with 4 people. Even the bathroom light wasn’t very bright. I would stay here again."
Robin 4-night trip
Posted 14 hours ago
Pier House Resort & Spa
Duval House

Duval House

8/10 Good
"I loved the gardens and pool in the back of the Inn. I also liked the fact it is located right on Duval St."
Cathrine 4-night trip
Posted 14 hours ago
Duval House
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

10/10 Excellent
"Great property"
Charlene 3-night trip
Posted 15 hours ago
Casa Marina Key West, Curio Collection by Hilton
Wicker Guesthouse

Wicker Guesthouse

10/10 Excellent
"Location was great"
Kathy 2-night trip
Posted 15 hours ago
Wicker Guesthouse
Douglas House - Adults Only

Douglas House - Adults Only

10/10 Excellent
"Great quiet place with great amenities pool beverages whatever you may need"
Theresa 3-night trip
Posted 1 day ago
Douglas House - Adults Only
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

8/10 Good
"Waterfront Parking cost"
Richard 2-night trip
Posted 2 days ago
Opal Key Resort & Marina, Key West
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

10/10 Excellent
"Place was great, clean, and reasonable. Beware the roosters at 6am but that might be the entire city of Key West Old Town"
Jason 2-night trip
Posted 2 days ago
Paradise Inn Key West - Adults Only

Other attractions near Florida Keys National Marine Sanctuary

An aquarium exhibit with fish tanks and informational displays.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
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A coastal fortification with a staircase leading to a higher platform, overlooking the sea.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
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The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a trip to Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
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Coffee Butler Amphitheater

You can make plans for a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.
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USCGC Ingham Maritime Museum

You can spend an afternoon browsing the exhibits at USCGC Ingham Maritime Museum during your trip to Key West.
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Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its entertainment choices.
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We Cycle Key West

You can do some window-shopping at We Cycle Key West during your stay in Key West.
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Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, cycling and lively festivals. If you're looking for a convenient place to stay, take a look at the 1487 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveller data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find near Florida Keys National Marine Sanctuary?
Expedia has 1487 hotels and other accommodation options within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum and Fort East Martello Museum and Gallery are some of the notable landmarks to see in the area. You can watch performances at Red Barn Theater, Coffee Butler Amphitheater and Key West Film Society if you're interested in local theatre.