What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

Top 10 Main Street Hotels of 2026

A cityscape at sunset with a mix of modern and older buildings, a clear sky, and a distant view of a flat landscape.

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Our top choices for Main Street hotels

A hotel with a prominent circular sign on top, multiple floors, and a well-lit entrance.

1. Residence Inn Ann Arbor Downtown

Downtown, < 0.1 km from Main Street

Laura

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen with a marble countertop, glass display cases, and neatly arranged plates and bowls.

2. AC Hotel Ann Arbor Downtown

Downtown, 0.3 km from Main Street

Peter

includes taxes & fees

18 Oct - 19 Oct

A bar area with a long wooden table, bar stools, a chandelier, and a chalkboard with mathematical equations.

3. Graduate by Hilton Ann Arbor

Kerrytown, 0.6 km from Main Street

Christopher

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, two chairs, a desk with a lamp, a telephone, and a framed picture on the wall.

4. Bell Tower Hotel

Central Campus Medical, 0.8 km from Main Street

Jennifer

includes taxes & fees

12 Oct - 13 Oct

A spacious hotel lobby with a modern design, featuring a large seating area, a bar, and a view of the cityscape through large windows.

5. Ann Arbor City Club Apartments

Downtown, 0.2 km from Main Street

Jeanne

includes taxes & fees

6 Oct - 7 Oct

A modern hotel lobby with a long dining table, multiple bar stools, a TV mounted on the wall, and a patterned carpet.

6. Hampton Inn & Suites Ann Arbor West

3.3 km from Main Street

JEFFREY

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

7. Homewood Suites by Hilton Ann Arbor

Bryant Pattengill East, 3.5 km from Main Street

Yogesh

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with a staircase, seating area, and large windows overlooking a street.

8. The Vanguard Ann Arbor, Autograph Collection

Old Fourth Ward, 1.1 km from Main Street

Kassandra

includes taxes & fees

18 Oct - 19 Oct

A garden with a variety of flowers and plants, a balcony with potted plants, and a green fence.

9. Ann Arbor B&B Inn

Old Fourth Ward, 0.9 km from Main Street

Adam

includes taxes & fees

2 Nov - 3 Nov

An outdoor seating area with tables and benches, a covered section with string lights, and a clear view of the street.

10. Home2 Suites By Hilton Ann Arbor South

4.3 km from Main Street

Timothy

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a modern design, featuring a mix of seating areas and a bar.

11. Hyatt Place Ann Arbor

Bryant Pattengill East, 4.6 km from Main Street

Stephen

includes taxes & fees

11 Oct - 12 Oct

A Hilton Garden Inn with outdoor seating, fire pits, and string lights.

12. Hilton Garden Inn Ann Arbor

4.8 km from Main Street

James

includes taxes & fees

29 Oct - 30 Oct

A spacious indoor pool area with a spiral staircase, lounge chairs, and a dining area with tables and chairs.

13. Weber's Hotel & Restaurant

3.6 km from Main Street

Denise

includes taxes & fees

6 Oct - 7 Oct

A modern interior with a wooden floor, a staircase with a metal railing, and a dining area with a table and chairs.

14. Stadium Suites

2.5 km from Main Street

Patrick

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with multiple lanes, surrounded by lounge chairs and a sunshade.

15. Wyndham Garden Ann Arbor

3.2 km from Main Street

Yvette

includes taxes & fees

2 Nov - 3 Nov

A large, multi-story stone house with a prominent red door, multiple windows, and a balcony.

16. Stone Chalet B&B Inn and Event Center

Baden-Ann Arbor Hills, 2.6 km from Main Street

Felice

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a bed, desk, chair, and a window with curtains.

17. TownePlace Suites by Marriott Ann Arbor

4.8 km from Main Street

Laurie

includes taxes & fees

8 Oct - 9 Oct

A hotel with a modern design, featuring a prominent 'spark by Hilton' sign, a covered entrance, and a well-maintained garden with various plants.

18. Spark by Hilton Ann Arbor South

Bryant Pattengill East, 4.8 km from Main Street

Jonathan

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a covered entrance, landscaped gardens, and a clear sky at dusk.

19. Microtel Inn & Suites by Wyndham Ann Arbor

5.5 km from Main Street

Clifford

includes taxes & fees

11 Oct - 12 Oct

A compact kitchen with a dining table, a microwave, a coffee maker, and a refrigerator.

20. Sonesta Simply Suites Detroit Ann Arbor

4.3 km from Main Street

Elizabeth

includes taxes & fees

25 Oct - 26 Oct

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Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

A football stadium filled with spectators, a large scoreboard, and a football field with the word "MICHIGAN" on it.

South Central

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

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A cityscape with a mix of historic and modern buildings, a prominent church, and a large parking area.

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

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A theater marquee with "Taylor & Co" and "Making Sense" displayed.

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Ann Arbor Art Center are top sights worth seeing.

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A modern building with vertical wooden slats and a traditional brick tower with arched windows.

Central Campus Medical

While visiting Central Campus Medical, you might make a stop by sights like University of Michigan Museum of Natural History and Hill Auditorium.

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A river with rocks, autumn foliage, and a bridge.

Burns Park

When in Burns Park, you can plan a visit to Yost Ice Arena and University of Michigan Museum of Natural History, some noteworthy sights in the nearby area.

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Top Main Street Hotel Reviews

Red Roof Inn Ann Arbor - U of Michigan South

10/10 Excellent

"The hotel was in a good location. It was a good value compared to other surrounding hotels."

Spark by Hilton Ann Arbor South

8/10 Good

"This was the first time my wife and I have stayed at this hotel. We came for a football game and got a good price here, as compared to other properties in Ann Arbor for a one night stay. The hotel is clean and quiet. That's very important. There is a pool and workout room. Since we had a brunch reservation, we didn't eat breakfast here. That said, I did go to get juice and the food offerings seemed quite limited. Overall, I would recommend this hotel, if the price is right."

Weber's Hotel & Restaurant

10/10 Excellent

"Came for a getaway and my stay was pleasant from my check-in to room service everything was fabulous. I didnt get to eat at the restaurant however I had service from my room and the food was good. I prefer it be HOT but still in was hot enough and delicious. The staff is attentive snd housekeeping as well"

Hotels in Main Street

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Our top choices for Main Street hotels

1. Residence Inn Ann Arbor Downtown

2. AC Hotel Ann Arbor Downtown

3. Graduate by Hilton Ann Arbor

4. Bell Tower Hotel

5. Ann Arbor City Club Apartments

6. Hampton Inn & Suites Ann Arbor West

7. Homewood Suites by Hilton Ann Arbor

8. The Vanguard Ann Arbor, Autograph Collection

9. Ann Arbor B&B Inn

10. Home2 Suites By Hilton Ann Arbor South

11. Hyatt Place Ann Arbor

12. Hilton Garden Inn Ann Arbor

13. Weber's Hotel & Restaurant

14. Stadium Suites

15. Wyndham Garden Ann Arbor

16. Stone Chalet B&B Inn and Event Center

17. TownePlace Suites by Marriott Ann Arbor

18. Spark by Hilton Ann Arbor South

19. Microtel Inn & Suites by Wyndham Ann Arbor

20. Sonesta Simply Suites Detroit Ann Arbor

Where to stay in Main Street

South Central

Bryant Pattengill East

Downtown

Central Campus Medical

Burns Park

Top Main Street Hotel Reviews

Red Roof Inn Ann Arbor - U of Michigan South

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