Find Luxury Hotels in Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City Luxury Hotels

Next weekend
In two weeks

Our top choices for Panama City luxury hotels

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (600 reviews)
"Beautiful place"
United States
Jose
The price is S$668
includes taxes & fees
10 Mar - 11 Mar
Sofitel Legend Casco Viejo, Panama City

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (276 reviews)
"The design, food, beverages and service of La Compania are incredible. "
United States
Beth
The price is S$590
includes taxes & fees
26 Mar - 27 Mar
Hotel La Compañía Casco Antiguo

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.4 out of 10, Good, (1,006 reviews)
"Everything was great very relaxing hotel staff very nice."
United States
Marica
The price is S$496
includes taxes & fees
28 Mar - 29 Mar
Dreams Playa Bonita Panama - All Inclusive

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is S$366
includes taxes & fees
1 Apr - 2 Apr
JW Marriott Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (667 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is S$374
includes taxes & fees
1 Apr - 2 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1,009 reviews)
"Location, amenities and staff were great."
United States
Orville
The price is S$398
includes taxes & fees
1 Apr - 2 Apr
Central Hotel Panama Casco Viejo

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,003 reviews)
"Beautiful property and amazing staff"
United States
CARMEN
The price is S$305
includes taxes & fees
29 Mar - 30 Mar
The Westin Playa Bonita Panama

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,439 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
The price is S$308
includes taxes & fees
15 Mar - 16 Mar
Megapolis Hotel Panamá

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,006 reviews)
"Second time staying and it was flawless."
United States
Anthony
The price is S$277
includes taxes & fees
31 Mar - 1 Apr
W Panama

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (666 reviews)
"Perfect location with attentive staff and nice rooms"
United States
Negar
The price is S$393
includes taxes & fees
17 Mar - 18 Mar
American Trade Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.

Top Panama City Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 23 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. W Panama and JW Marriott Panama are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 23 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Crown Casino.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina and Santo Tomas Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.

Explore a world of travel with Expedia