A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Luxury Hotels

Tonight
1 Sept - 2 Sept
Tomorrow
2 Sept - 3 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Panama City luxury hotels

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
S$486
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City

2. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
S$474
includes taxes & fees
17 Sept - 18 Sept
Hotel La Compañía Casco Antiguo

3. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
S$369
includes taxes & fees
20 Sept - 21 Sept
JW Marriott Panama

4. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
S$323
includes taxes & fees
25 Sept - 26 Sept
W Panama

5. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
S$376
includes taxes & fees
30 Sept - 1 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

6. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
S$337
includes taxes & fees
22 Sept - 23 Sept
Hilton Panama

7. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
S$372
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama

8. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
S$347
includes taxes & fees
2 Sept - 3 Sept
Dreams Playa Bonita Panama - All Inclusive

9. American Trade Hotel

American Trade Hotel
Casco Viejo
  • A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
S$344
includes taxes & fees
8 Sept - 9 Sept
American Trade Hotel

10. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
S$326
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency Panama City
View all properties

Top Panama City Hotel Reviews

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"I have read some bad reviews on this location, however, I had a very good experience during my ten days stay!"
Mark 6-night trip
Posted less than an hour ago
Courtyard by Marriott Panama Multiplaza Mall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"The staff at the pool area was great."
David 4-night trip
Posted 1 hour ago
Hotel Riu Plaza Panama
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

8/10 Good
"El personal fue increíblemente atento y amable. Las facilidades estaban limpias pero le hace falta un cariñito, debe ser remodelado. El aire acondicionado no enfría mucho y el agua caliente no estaba funcionando. La comida, excelente!"
Maria 5-night trip
Posted 10 hours ago
Hospedium Princess Hotel Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"The property was fine. The breakfast was nice, but not excellent. The room and view were fine, the spa was not open, nor was there any alternative for massage , steam, etc. overall a very good value and I would stay here again."
Dwight 4-night trip
Posted 13 hours ago
Decapolis Hotel Panama City
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

8/10 Good
"Best thing about the hotel was the nice staff and the rooms are very spacious. But area is not the greateast.....lot of abandoned buildings around....feels a bit worn down."
Britta 6-night trip
Posted 1 day ago
Radisson Hotel Panama Canal
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Room was very clean and comfortable."
Meredith 1-night trip
Posted 1 day ago
JW Marriott Panama
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"-"
Solomon 5-night trip
Posted 2 days ago
Renaissance Panama City Hotel

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Multicentro Panama.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina Station and Santo Tomás Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.

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