A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Luxury Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Panama City luxury hotels

A balcony with a table, chairs, and a view of a city skyline across a body of water.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.

1. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
S$489
includes taxes & fees
21 Oct - 22 Oct
Sofitel Legend Casco Viejo, Panama City
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

2. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
S$393
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A hotel entrance with a central water feature, seating areas, and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
S$433
includes taxes & fees
2 Nov - 3 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A bar area with multiple seating options, a bar counter, and a fireplace.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

4. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
S$370
includes taxes & fees
18 Oct - 19 Oct
Hotel La Compañía Casco Antiguo
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A modern bar area with seating and a view of the city.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

5. Hilton Panama

Hilton Panama
Bella Vista
  • Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
S$370
includes taxes & fees
8 Nov - 9 Nov
Hilton Panama
A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.

6. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
S$199
includes taxes & fees
3 Nov - 4 Nov
Crowne Plaza Panama Airport by IHG
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.

7. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
  • Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
S$370
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A high-rise building with a rooftop pool area, surrounded by other buildings.

8. W Panama

W Panama
Bella Vista
  • Lavish urban retreat offers 3 hot tubs, poolside luxury, and concierge services in Panama city.
S$325
includes taxes & fees
1 Nov - 2 Nov
W Panama
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

9. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
S$199
includes taxes & fees
27 Oct - 28 Oct
Hotel Riu Plaza Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern building with a sign reading 'HYATT REGENCY.'
A spacious hotel lobby with modern furniture, large windows, and a city view.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.

10. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
S$263
includes taxes & fees
25 Oct - 26 Oct
Hyatt Regency Panama City
View all properties

Top Panama City Hotel Reviews

Hotel Ojos del Rio

Hotel Ojos del Rio

8/10 Good
"Rooms would be better with pressing iron and iron board. TV should be set to primary language of visitors."
Kyle 7-night trip
Posted less than an hour ago
Hotel Ojos del Rio
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Room was always Clean Friendly Staff Great Hotel"
Jermaine Jarrod 7-night trip
Posted 6 hours ago
Hotel Riu Plaza Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"Food was limited, but I enjoyed our stay ..3"
Mechalia 4-night trip
Posted 1 day ago
Decapolis Hotel Panama City
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"best hotel to stay when you visit panama city"
Ahmed 1-night trip
Posted 1 day ago
JW Marriott Panama

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Panama City?
Arrange a flight into Panama City (PAC-Marcos A. Gelabert Intl.) Airport or Balboa (BLB-Panama Pacifico Intl.) Airport, and then treat yourself to a stay at one of 24 luxurious hotels. Known for its casinos and shopping, Panama City also has some interesting things to see and do including Albrook Shopping Mall, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Panama City?
Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Megapolis Hotel Panamá and Hyatt Regency Panama City are other upscale choices for your trip.
How many luxury hotels should I expect to find in Panama City?
Lie in the lap of luxury during your getaway to Panama City in one of Expedia's 24 luxury hotels.
When can I expect good weather in Panama City?
Planning for the weather is a good way to make your trip to Panama City relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Panama City are July, August, June and November, with each month seeing an average of 369 mm of rainfall.
What's there to see and do in Panama City?
Experience Panama City and visit Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have spare time during your trip, you might want to make a stop at Uruguay Street and Avenida Balboa.
How can I get around Panama City?
It's easier to get around town in style when you know your options. Walk to nearby metro stations such as Iglesia del Carmen Station, Vía Argentina Station and Santo Tomás Station. If you want to explore the larger area, hop on a train at Panama City Passenger Station.

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